Matches in SemOpenAlex for { <https://semopenalex.org/work/W4206991842> ?p ?o ?g. }
- W4206991842 endingPage "3092" @default.
- W4206991842 startingPage "3082" @default.
- W4206991842 abstract "Acute myocardial infarction (AMI) is characterized by high morbidity and mortality rates. Circular RNAs collectively participate in the initiation and development of AMI. The purpose of this study was to investigate the role of circRbms1 in AMI. Ischemia-reperfusion (I/R) was performed to establish an AMI model. RT-qPCR and Western blotting were performed to detect mRNA and analyze protein expression, respectively. The interaction between miR-92a and circRbms1/BCL2L11 was confirmed by luciferase and RNA pull-down assays. circRbms1 is overexpressed in AMI. However, circRbms1 knockdown alleviated H9c2 cell apoptosis and reduced the release of reactive oxygen species. circRbms1 targeted miR-92a, the downregulation of which alleviated the effects of circRbms1 knockdown and increased oxidative stress and H9c2 cell apoptosis. Moreover, circRbms1 sponged miR-92a to upregulate BCL2L11, which modulated the expression of apoptosis-related genes. circRbms1 participated in myocardial I/R injury by regulating the miR-92a/BCL2L11 signaling pathway, which may provide a new strategy for the treatment of AMI." @default.
- W4206991842 created "2022-01-26" @default.
- W4206991842 creator A5003598854 @default.
- W4206991842 creator A5004616491 @default.
- W4206991842 creator A5028403326 @default.
- W4206991842 creator A5032350652 @default.
- W4206991842 creator A5089666784 @default.
- W4206991842 date "2022-01-22" @default.
- W4206991842 modified "2023-10-05" @default.
- W4206991842 title "Circular RNA Rbms1 inhibited the development of myocardial ischemia reperfusion injury by regulating miR-92a/BCL2L11 signaling pathway" @default.
- W4206991842 cites W1698414284 @default.
- W4206991842 cites W1918887753 @default.
- W4206991842 cites W2080808874 @default.
- W4206991842 cites W2126140941 @default.
- W4206991842 cites W2141570739 @default.
- W4206991842 cites W2325596649 @default.
- W4206991842 cites W2412480337 @default.
- W4206991842 cites W2438551086 @default.
- W4206991842 cites W2464382898 @default.
- W4206991842 cites W2559818093 @default.
- W4206991842 cites W2582821178 @default.
- W4206991842 cites W2605363845 @default.
- W4206991842 cites W2729533505 @default.
- W4206991842 cites W2734285790 @default.
- W4206991842 cites W2761136162 @default.
- W4206991842 cites W2793830108 @default.
- W4206991842 cites W2796464268 @default.
- W4206991842 cites W2805006572 @default.
- W4206991842 cites W2897342629 @default.
- W4206991842 cites W2901308849 @default.
- W4206991842 cites W2901423686 @default.
- W4206991842 cites W2906924607 @default.
- W4206991842 cites W2915933137 @default.
- W4206991842 cites W2917946944 @default.
- W4206991842 cites W2939320704 @default.
- W4206991842 cites W2954118205 @default.
- W4206991842 cites W2969228284 @default.
- W4206991842 cites W2971872062 @default.
- W4206991842 cites W2972838253 @default.
- W4206991842 cites W2980477014 @default.
- W4206991842 cites W2980572613 @default.
- W4206991842 cites W2986960561 @default.
- W4206991842 cites W2988362774 @default.
- W4206991842 cites W2991410006 @default.
- W4206991842 cites W2992413241 @default.
- W4206991842 cites W2997846402 @default.
- W4206991842 cites W3000222929 @default.
- W4206991842 cites W3037699130 @default.
- W4206991842 cites W3038635558 @default.
- W4206991842 cites W3041193269 @default.
- W4206991842 cites W3041821205 @default.
- W4206991842 cites W3042688726 @default.
- W4206991842 cites W3114058350 @default.
- W4206991842 cites W3116884569 @default.
- W4206991842 cites W3197886061 @default.
- W4206991842 cites W3198926630 @default.
- W4206991842 cites W79815117 @default.
- W4206991842 cites W83646335 @default.
- W4206991842 doi "https://doi.org/10.1080/21655979.2022.2025696" @default.
- W4206991842 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35068339" @default.
- W4206991842 hasPublicationYear "2022" @default.
- W4206991842 type Work @default.
- W4206991842 citedByCount "14" @default.
- W4206991842 countsByYear W42069918422022 @default.
- W4206991842 countsByYear W42069918422023 @default.
- W4206991842 crossrefType "journal-article" @default.
- W4206991842 hasAuthorship W4206991842A5003598854 @default.
- W4206991842 hasAuthorship W4206991842A5004616491 @default.
- W4206991842 hasAuthorship W4206991842A5028403326 @default.
- W4206991842 hasAuthorship W4206991842A5032350652 @default.
- W4206991842 hasAuthorship W4206991842A5089666784 @default.
- W4206991842 hasBestOaLocation W42069918421 @default.
- W4206991842 hasConcept C104317684 @default.
- W4206991842 hasConcept C105580179 @default.
- W4206991842 hasConcept C126322002 @default.
- W4206991842 hasConcept C127561419 @default.
- W4206991842 hasConcept C145059251 @default.
- W4206991842 hasConcept C173396325 @default.
- W4206991842 hasConcept C185592680 @default.
- W4206991842 hasConcept C190283241 @default.
- W4206991842 hasConcept C2780114680 @default.
- W4206991842 hasConcept C48349386 @default.
- W4206991842 hasConcept C500558357 @default.
- W4206991842 hasConcept C541997718 @default.
- W4206991842 hasConcept C55493867 @default.
- W4206991842 hasConcept C62478195 @default.
- W4206991842 hasConcept C71924100 @default.
- W4206991842 hasConcept C85265743 @default.
- W4206991842 hasConcept C86803240 @default.
- W4206991842 hasConcept C95444343 @default.
- W4206991842 hasConceptScore W4206991842C104317684 @default.
- W4206991842 hasConceptScore W4206991842C105580179 @default.
- W4206991842 hasConceptScore W4206991842C126322002 @default.
- W4206991842 hasConceptScore W4206991842C127561419 @default.
- W4206991842 hasConceptScore W4206991842C145059251 @default.
- W4206991842 hasConceptScore W4206991842C173396325 @default.
- W4206991842 hasConceptScore W4206991842C185592680 @default.
- W4206991842 hasConceptScore W4206991842C190283241 @default.