Matches in SemOpenAlex for { <https://semopenalex.org/work/W4206993847> ?p ?o ?g. }
- W4206993847 abstract "Abundant connectivity among organic ligands and inorganic metal ions makes the physical and chemical characters of metal-organic frameworks (MOFs) could be precisely devised and modulated for specific applications. Especially nanoscale MOFs (NMOFs), a unique family of hybrid nanomaterials, with merits of holding the nature as the mainstay MOFs and demonstrating particle size in nanoscale range which enable them prospect platform in clinic. Adjustability of composition and structure allows NMOFs with different constituents, shapes, and characteristics. Oriented frameworks and highly porous provide enough space for packing therapeutic cargoes and various imaging agents efficiently. Moreover, the relatively labile metal-ligand bonds make NMOFs biodegradable in nature. So far, as a significant class of biomedically relevant nanomaterials, NMOFs have been explored as drug carriers, therapeutic preparation, and biosensing and imaging preparation owing to their high porosity, multifunctionality, and biocompatibility. This review provides up-to-date developments of NMOFs in biomedical applications with emphasis on size control, synthetic approaches, and surfaces functionalization as well as stability, degradation, and toxicity. The outlooks and several crucial issues of this area are also discussed, with the expectation that it may help arouse widespread attention on exploring NMOFs in potential clinical applications." @default.
- W4206993847 created "2022-01-26" @default.
- W4206993847 creator A5007658109 @default.
- W4206993847 creator A5032180121 @default.
- W4206993847 creator A5074916544 @default.
- W4206993847 creator A5087937843 @default.
- W4206993847 date "2022-01-24" @default.
- W4206993847 modified "2023-10-15" @default.
- W4206993847 title "Nanoscale Metal−Organic Frameworks and Their Nanomedicine Applications" @default.
- W4206993847 cites W1762545184 @default.
- W4206993847 cites W1868754155 @default.
- W4206993847 cites W1878959896 @default.
- W4206993847 cites W1909516596 @default.
- W4206993847 cites W1967551950 @default.
- W4206993847 cites W1968377063 @default.
- W4206993847 cites W1984390639 @default.
- W4206993847 cites W1988089309 @default.
- W4206993847 cites W1993193556 @default.
- W4206993847 cites W1996352962 @default.
- W4206993847 cites W1996869669 @default.
- W4206993847 cites W2002449355 @default.
- W4206993847 cites W2018573261 @default.
- W4206993847 cites W2023784263 @default.
- W4206993847 cites W2032105134 @default.
- W4206993847 cites W2034265743 @default.
- W4206993847 cites W2041270553 @default.
- W4206993847 cites W2042138520 @default.
- W4206993847 cites W2046741458 @default.
- W4206993847 cites W2051986908 @default.
- W4206993847 cites W2054745605 @default.
- W4206993847 cites W2061594767 @default.
- W4206993847 cites W2063482702 @default.
- W4206993847 cites W2065282169 @default.
- W4206993847 cites W2066991705 @default.
- W4206993847 cites W2080376276 @default.
- W4206993847 cites W2084063536 @default.
- W4206993847 cites W2091385634 @default.
- W4206993847 cites W2092476734 @default.
- W4206993847 cites W2099761318 @default.
- W4206993847 cites W2103204348 @default.
- W4206993847 cites W2112097827 @default.
- W4206993847 cites W2116303692 @default.
- W4206993847 cites W2135311871 @default.
- W4206993847 cites W2162207609 @default.
- W4206993847 cites W2166133072 @default.
- W4206993847 cites W2170811673 @default.
- W4206993847 cites W2171160812 @default.
- W4206993847 cites W2208284809 @default.
- W4206993847 cites W2215498278 @default.
- W4206993847 cites W2233111737 @default.
- W4206993847 cites W2258838563 @default.
- W4206993847 cites W2269160102 @default.
- W4206993847 cites W2278059930 @default.
- W4206993847 cites W2279490582 @default.
- W4206993847 cites W2296648202 @default.
- W4206993847 cites W2301837025 @default.
- W4206993847 cites W2320312730 @default.
- W4206993847 cites W2327712306 @default.
- W4206993847 cites W2330395753 @default.
- W4206993847 cites W2333242525 @default.
- W4206993847 cites W2339094010 @default.
- W4206993847 cites W2344130877 @default.
- W4206993847 cites W2345131454 @default.
- W4206993847 cites W2345673877 @default.
- W4206993847 cites W2346308186 @default.
- W4206993847 cites W2396819506 @default.
- W4206993847 cites W2398109561 @default.
- W4206993847 cites W2410849299 @default.
- W4206993847 cites W2410900281 @default.
- W4206993847 cites W2414123584 @default.
- W4206993847 cites W2428082214 @default.
- W4206993847 cites W2503953373 @default.
- W4206993847 cites W2511068407 @default.
- W4206993847 cites W2513282319 @default.
- W4206993847 cites W2518647629 @default.
- W4206993847 cites W2530743089 @default.
- W4206993847 cites W2554176825 @default.
- W4206993847 cites W2560781979 @default.
- W4206993847 cites W2564841767 @default.
- W4206993847 cites W2574687138 @default.
- W4206993847 cites W2579451396 @default.
- W4206993847 cites W2581594191 @default.
- W4206993847 cites W2582001567 @default.
- W4206993847 cites W2585315127 @default.
- W4206993847 cites W2585464736 @default.
- W4206993847 cites W2588241702 @default.
- W4206993847 cites W2588708434 @default.
- W4206993847 cites W2589886361 @default.
- W4206993847 cites W2593132567 @default.
- W4206993847 cites W2594479214 @default.
- W4206993847 cites W2597536258 @default.
- W4206993847 cites W2602228571 @default.
- W4206993847 cites W2603383977 @default.
- W4206993847 cites W2604084092 @default.
- W4206993847 cites W2604582212 @default.
- W4206993847 cites W2606675993 @default.
- W4206993847 cites W2609455338 @default.
- W4206993847 cites W2614976445 @default.
- W4206993847 cites W2617943034 @default.
- W4206993847 cites W2728952808 @default.