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- W4207028462 abstract "Ovarian cancer (OC), an important cause of cancer-related death in women worldwide, is one of the most malignant cancers and is characterized by a poor prognosis. RNA-binding proteins (RBPs), a class of endogenous proteins that can bind to mRNAs and modify (or even determine) the amount of protein they can generate, have attracted great attention in the context of various diseases, especially cancers. Compelling studies have suggested that RBPs are aberrantly expressed in different cancer tissues and cell types, including OC tissues and cells. More specifically, RBPs can regulate proliferation, apoptosis, invasion, metastasis, tumorigenesis and chemosensitivity and serve as potential therapeutic targets in OC. Herein, we summarize what is currently known about the biogenesis, molecular functions and potential roles of human RBPs in OC and their prospects for application in the clinical treatment of OC." @default.
- W4207028462 created "2022-01-26" @default.
- W4207028462 creator A5006887861 @default.
- W4207028462 creator A5028160312 @default.
- W4207028462 creator A5053499506 @default.
- W4207028462 creator A5079160849 @default.
- W4207028462 creator A5089296993 @default.
- W4207028462 date "2022-01-21" @default.
- W4207028462 modified "2023-10-02" @default.
- W4207028462 title "RNA-binding proteins in ovarian cancer: a novel avenue of their roles in diagnosis and treatment" @default.
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