Matches in SemOpenAlex for { <https://semopenalex.org/work/W4207037688> ?p ?o ?g. }
- W4207037688 endingPage "1533" @default.
- W4207037688 startingPage "1524" @default.
- W4207037688 abstract "The world is aging and with it an associated increase in malignancies. Haematological malignancies especially Acute Myeloid Leukemia (AML) are no exception to this trend. With scientific advances, development of new AML treatments has improved patient mortality. One future research interest would be Leukeamic Stem Cells (LSC). This review aims to briefly highlight main LSC characteristics and their relationship with hematopoietic stem cells. Key LSC characteristics include dysregulated apoptosis, capacity for self-renewal, genomic instability, dysregulated energetics, immune privilege and an altered tumor microenvironment. Similar characteristics are also found in HSCs though in a regulated form. Classifying these characteristics will aid in the development of clinical biomarkers for LSC which is a potential clinical application of LSC biology. LSC biomarkers might prove to be critical in future AML management through improving accuracy of AML diagnosis, providing targeted treatment to minimize side effects, refinement of prognosis and relapse risk for earlier intervention." @default.
- W4207037688 created "2022-01-26" @default.
- W4207037688 creator A5068622479 @default.
- W4207037688 date "2022-01-22" @default.
- W4207037688 modified "2023-09-26" @default.
- W4207037688 title "Relationship between leukaemic stem cells and hematopoietic stem cells and their clinical application" @default.
- W4207037688 cites W1255676896 @default.
- W4207037688 cites W1966982061 @default.
- W4207037688 cites W1974182237 @default.
- W4207037688 cites W1985187342 @default.
- W4207037688 cites W1991962444 @default.
- W4207037688 cites W1992320498 @default.
- W4207037688 cites W1994648009 @default.
- W4207037688 cites W1995438296 @default.
- W4207037688 cites W1995652309 @default.
- W4207037688 cites W1996220028 @default.
- W4207037688 cites W1998367819 @default.
- W4207037688 cites W1999149570 @default.
- W4207037688 cites W2001535881 @default.
- W4207037688 cites W2004443250 @default.
- W4207037688 cites W2006445674 @default.
- W4207037688 cites W2026721712 @default.
- W4207037688 cites W2035197415 @default.
- W4207037688 cites W2043306142 @default.
- W4207037688 cites W2047122678 @default.
- W4207037688 cites W2048385227 @default.
- W4207037688 cites W2051011734 @default.
- W4207037688 cites W2053334450 @default.
- W4207037688 cites W2054086725 @default.
- W4207037688 cites W2055879533 @default.
- W4207037688 cites W2070387456 @default.
- W4207037688 cites W2071754840 @default.
- W4207037688 cites W2072633261 @default.
- W4207037688 cites W2073440691 @default.
- W4207037688 cites W2074516296 @default.
- W4207037688 cites W2076031927 @default.
- W4207037688 cites W2076966192 @default.
- W4207037688 cites W2087734794 @default.
- W4207037688 cites W2087762900 @default.
- W4207037688 cites W2090982381 @default.
- W4207037688 cites W2092599098 @default.
- W4207037688 cites W2096148594 @default.
- W4207037688 cites W2119345707 @default.
- W4207037688 cites W2126816979 @default.
- W4207037688 cites W2131157723 @default.
- W4207037688 cites W2137605834 @default.
- W4207037688 cites W2137715553 @default.
- W4207037688 cites W2144822384 @default.
- W4207037688 cites W2146726947 @default.
- W4207037688 cites W2160191948 @default.
- W4207037688 cites W2165805414 @default.
- W4207037688 cites W2166972450 @default.
- W4207037688 cites W2204155422 @default.
- W4207037688 cites W2252841155 @default.
- W4207037688 cites W2337848504 @default.
- W4207037688 cites W2339658711 @default.
- W4207037688 cites W2419140434 @default.
- W4207037688 cites W2426586472 @default.
- W4207037688 cites W2473447250 @default.
- W4207037688 cites W2507272148 @default.
- W4207037688 cites W2587571866 @default.
- W4207037688 cites W2605757478 @default.
- W4207037688 cites W2622063078 @default.
- W4207037688 cites W267482784 @default.
- W4207037688 cites W2747344355 @default.
- W4207037688 cites W2797049355 @default.
- W4207037688 cites W2806760348 @default.
- W4207037688 cites W2807346792 @default.
- W4207037688 cites W2899272142 @default.
- W4207037688 cites W2899711966 @default.
- W4207037688 cites W2958014316 @default.
- W4207037688 cites W3021625969 @default.
- W4207037688 cites W3093815480 @default.
- W4207037688 cites W3111839605 @default.
- W4207037688 cites W3133716805 @default.
- W4207037688 doi "https://doi.org/10.1080/10428194.2022.2027401" @default.
- W4207037688 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35067128" @default.
- W4207037688 hasPublicationYear "2022" @default.
- W4207037688 type Work @default.
- W4207037688 citedByCount "0" @default.
- W4207037688 crossrefType "journal-article" @default.
- W4207037688 hasAuthorship W4207037688A5068622479 @default.
- W4207037688 hasConcept C109159458 @default.
- W4207037688 hasConcept C143998085 @default.
- W4207037688 hasConcept C194409129 @default.
- W4207037688 hasConcept C203014093 @default.
- W4207037688 hasConcept C2778086970 @default.
- W4207037688 hasConcept C2778461978 @default.
- W4207037688 hasConcept C2778729363 @default.
- W4207037688 hasConcept C2779282312 @default.
- W4207037688 hasConcept C28328180 @default.
- W4207037688 hasConcept C502942594 @default.
- W4207037688 hasConcept C54355233 @default.
- W4207037688 hasConcept C60644358 @default.
- W4207037688 hasConcept C71924100 @default.
- W4207037688 hasConcept C86803240 @default.
- W4207037688 hasConceptScore W4207037688C109159458 @default.
- W4207037688 hasConceptScore W4207037688C143998085 @default.