Matches in SemOpenAlex for { <https://semopenalex.org/work/W4207040333> ?p ?o ?g. }
- W4207040333 endingPage "1980" @default.
- W4207040333 startingPage "1967" @default.
- W4207040333 abstract "The syndrome of thrombotic microangiopathy (TMA) is a clinical-pathological entity characterized by microangiopathic hemolytic anemia, thrombocytopenia, and end organ involvement. It comprises a spectrum of underlying etiologies that may differ in children and adults. In children, apart from ruling out shigatoxin-associated hemolytic uremic syndrome (HUS) and other infection-associated TMA like Streptococcus pneumoniae-HUS, rare inherited causes including complement-associated HUS, cobalamin defects, and mutations in diacylglycerol kinase epsilon gene must be investigated. TMA should also be considered in the setting of solid organ or hematopoietic stem cell transplantation. In this review, acquired and inherited causes of TMA are described with a focus on particularities of the main causes of TMA in children. A pragmatic approach that may help the clinician tailor evaluation and management is provided. The described approach will allow for early initiation of treatment while waiting for the definitive diagnosis of the underlying TMA." @default.
- W4207040333 created "2022-01-26" @default.
- W4207040333 creator A5016838436 @default.
- W4207040333 creator A5017624325 @default.
- W4207040333 creator A5046695529 @default.
- W4207040333 creator A5058170631 @default.
- W4207040333 creator A5070946918 @default.
- W4207040333 date "2022-01-18" @default.
- W4207040333 modified "2023-10-16" @default.
- W4207040333 title "Thrombotic microangiopathy in children" @default.
- W4207040333 cites W1560197429 @default.
- W4207040333 cites W1685331907 @default.
- W4207040333 cites W1963905188 @default.
- W4207040333 cites W1964443013 @default.
- W4207040333 cites W1966590389 @default.
- W4207040333 cites W1977427621 @default.
- W4207040333 cites W1982003857 @default.
- W4207040333 cites W1988048931 @default.
- W4207040333 cites W1997303422 @default.
- W4207040333 cites W1999336316 @default.
- W4207040333 cites W2003953496 @default.
- W4207040333 cites W2017235356 @default.
- W4207040333 cites W2024751825 @default.
- W4207040333 cites W2031628865 @default.
- W4207040333 cites W2038181025 @default.
- W4207040333 cites W2041065426 @default.
- W4207040333 cites W2046603339 @default.
- W4207040333 cites W2059824394 @default.
- W4207040333 cites W2071227748 @default.
- W4207040333 cites W2096322533 @default.
- W4207040333 cites W2106675927 @default.
- W4207040333 cites W2113219905 @default.
- W4207040333 cites W2113851616 @default.
- W4207040333 cites W2118510193 @default.
- W4207040333 cites W2121178096 @default.
- W4207040333 cites W2123753762 @default.
- W4207040333 cites W2123994723 @default.
- W4207040333 cites W2134399985 @default.
- W4207040333 cites W2138062831 @default.
- W4207040333 cites W2144398438 @default.
- W4207040333 cites W2147498528 @default.
- W4207040333 cites W2149330659 @default.
- W4207040333 cites W2159478521 @default.
- W4207040333 cites W2159868280 @default.
- W4207040333 cites W2159884188 @default.
- W4207040333 cites W2166637331 @default.
- W4207040333 cites W2171275709 @default.
- W4207040333 cites W2225522108 @default.
- W4207040333 cites W2264090971 @default.
- W4207040333 cites W2305176160 @default.
- W4207040333 cites W2317056394 @default.
- W4207040333 cites W2334213116 @default.
- W4207040333 cites W2338852046 @default.
- W4207040333 cites W2367139825 @default.
- W4207040333 cites W2529701506 @default.
- W4207040333 cites W2557184605 @default.
- W4207040333 cites W2565152113 @default.
- W4207040333 cites W2573742095 @default.
- W4207040333 cites W2588604281 @default.
- W4207040333 cites W2590258299 @default.
- W4207040333 cites W2593388942 @default.
- W4207040333 cites W2604565584 @default.
- W4207040333 cites W2758138742 @default.
- W4207040333 cites W2788787799 @default.
- W4207040333 cites W2791657471 @default.
- W4207040333 cites W2807740363 @default.
- W4207040333 cites W2811279557 @default.
- W4207040333 cites W2885691825 @default.
- W4207040333 cites W2897888015 @default.
- W4207040333 cites W2898456742 @default.
- W4207040333 cites W2899480563 @default.
- W4207040333 cites W2910737538 @default.
- W4207040333 cites W2943893614 @default.
- W4207040333 cites W2944394188 @default.
- W4207040333 cites W2946176087 @default.
- W4207040333 cites W2947879705 @default.
- W4207040333 cites W2950482522 @default.
- W4207040333 cites W2954337609 @default.
- W4207040333 cites W2968187385 @default.
- W4207040333 cites W2971085835 @default.
- W4207040333 cites W2972641064 @default.
- W4207040333 cites W3000105648 @default.
- W4207040333 cites W3003441037 @default.
- W4207040333 cites W3009426607 @default.
- W4207040333 cites W3009429865 @default.
- W4207040333 cites W3015716501 @default.
- W4207040333 cites W3020196201 @default.
- W4207040333 cites W3024221030 @default.
- W4207040333 cites W3035951166 @default.
- W4207040333 cites W3037524016 @default.
- W4207040333 cites W3039188523 @default.
- W4207040333 cites W3043054231 @default.
- W4207040333 cites W3046868155 @default.
- W4207040333 cites W3093678484 @default.
- W4207040333 cites W3102223165 @default.
- W4207040333 cites W3105679468 @default.
- W4207040333 cites W3108107578 @default.
- W4207040333 cites W3124017177 @default.