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- W4207044329 abstract "For patients with multiple myeloma who are eligible for high-dose melphalan therapy and autologous stem cell transplant (ASCT), the strategy of maintenance with low-dose lenalidomide therapy has become the current standard of care. However, this strategy is not curative, and many unanswered questions remain regarding the optimization of lenalidomide-based maintenance therapy.In this review, we evaluate the current data supporting the use of lenalidomide maintenance, either alone or in combination, following ASCT. We provide an overview of the management of lenalidomide-associated toxicities as well as address the unresolved topics of optimal treatment duration and use of minimal residual disease assessment.While single-agent lenalidomide maintenance is a current standard of care, a one-size-fits-all approach to maintenance therapy is not optimal. The rapidly evolving landscape of multiple myeloma therapy in conjunction with ongoing clinical trials should enable a future where an individualized approach based on disease characteristics, response to induction and ASCT (or even non-ASCT consolidation approaches such as CAR T-cell therapy or bispecific antibodies), as well as patient preferences will influence the use of lenalidomide maintenance." @default.
- W4207044329 created "2022-01-26" @default.
- W4207044329 creator A5005732386 @default.
- W4207044329 creator A5008457586 @default.
- W4207044329 date "2022-01-02" @default.
- W4207044329 modified "2023-10-18" @default.
- W4207044329 title "The era of lenalidomide maintenance therapy in multiple myeloma: settings for achieving best outcomes" @default.
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- W4207044329 cites W1955899532 @default.
- W4207044329 cites W1977450917 @default.
- W4207044329 cites W1982855701 @default.
- W4207044329 cites W1986297232 @default.
- W4207044329 cites W1997952190 @default.
- W4207044329 cites W1999088487 @default.
- W4207044329 cites W2000047150 @default.
- W4207044329 cites W2015345028 @default.
- W4207044329 cites W2023487324 @default.
- W4207044329 cites W2025656486 @default.
- W4207044329 cites W2033671876 @default.
- W4207044329 cites W2037560732 @default.
- W4207044329 cites W2044835347 @default.
- W4207044329 cites W2049869153 @default.
- W4207044329 cites W2055028613 @default.
- W4207044329 cites W2059837228 @default.
- W4207044329 cites W2059873406 @default.
- W4207044329 cites W2065974097 @default.
- W4207044329 cites W2068412287 @default.
- W4207044329 cites W2088515900 @default.
- W4207044329 cites W2091253809 @default.
- W4207044329 cites W2097331346 @default.
- W4207044329 cites W2101603234 @default.
- W4207044329 cites W2122728054 @default.
- W4207044329 cites W2125721471 @default.
- W4207044329 cites W2128084036 @default.
- W4207044329 cites W2132258376 @default.
- W4207044329 cites W2136993970 @default.
- W4207044329 cites W2139260559 @default.
- W4207044329 cites W2141602720 @default.
- W4207044329 cites W2143425592 @default.
- W4207044329 cites W2148758597 @default.
- W4207044329 cites W2149858388 @default.
- W4207044329 cites W2170210178 @default.
- W4207044329 cites W2293740089 @default.
- W4207044329 cites W2462945035 @default.
- W4207044329 cites W2518827451 @default.
- W4207044329 cites W2604776612 @default.
- W4207044329 cites W2735078070 @default.
- W4207044329 cites W2737964630 @default.
- W4207044329 cites W2746456353 @default.
- W4207044329 cites W2858942837 @default.
- W4207044329 cites W2893245372 @default.
- W4207044329 cites W2904294860 @default.
- W4207044329 cites W2909552152 @default.
- W4207044329 cites W2913321588 @default.
- W4207044329 cites W2913887128 @default.
- W4207044329 cites W2955507058 @default.
- W4207044329 cites W2973211951 @default.
- W4207044329 cites W2979514350 @default.
- W4207044329 cites W2980015215 @default.
- W4207044329 cites W2980634008 @default.
- W4207044329 cites W2980944048 @default.
- W4207044329 cites W2987632797 @default.
- W4207044329 cites W2990816134 @default.
- W4207044329 cites W3006850578 @default.
- W4207044329 cites W3017057237 @default.
- W4207044329 cites W3019889711 @default.
- W4207044329 cites W3021098306 @default.
- W4207044329 cites W3029080165 @default.
- W4207044329 cites W3035594055 @default.
- W4207044329 cites W3069281433 @default.
- W4207044329 cites W3095389126 @default.
- W4207044329 cites W3097115410 @default.
- W4207044329 cites W3097144589 @default.
- W4207044329 cites W3097539251 @default.
- W4207044329 cites W3113412439 @default.
- W4207044329 cites W3153280867 @default.
- W4207044329 cites W3162395942 @default.
- W4207044329 cites W3164224366 @default.
- W4207044329 cites W3164261129 @default.
- W4207044329 cites W3169934767 @default.
- W4207044329 cites W3173150656 @default.
- W4207044329 cites W3188071931 @default.
- W4207044329 cites W3200559356 @default.
- W4207044329 cites W3212617436 @default.
- W4207044329 cites W3213350456 @default.
- W4207044329 cites W4225943158 @default.
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- W4207044329 doi "https://doi.org/10.1080/17512433.2022.2032656" @default.
- W4207044329 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35061547" @default.
- W4207044329 hasPublicationYear "2022" @default.
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