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- W4207058677 abstract "ObjectivesThis study aims to describe the distribution of anchor-based minimal important change (MIC) estimates in standard deviation (SD) units and examine if the robustness of such estimates depends on the specific SD used or on the methodological credibility of the anchor-based estimates.Design and SettingWe included all anchor-based MIC estimates from studies published in MEDLINE and relevant literature databases upto October 2018. Each MIC was converted to SD units using baseline, endpoint, and change from baseline SDs. We performed a descriptive analysis of MICs in SD units and checked how the distribution would change if MICs with low methodological credibility were excluded from the analysis.ResultsWe included 1,009 MIC estimates from 182 studies. The medians and interquartile ranges of MICs in SD units were 0.43 (0.25 to 0.69), 0.42 (0.22 to 0.70), and 0.51 (0.28 to 0.78) for baseline, endpoint, and change SD units, respectively. Some MICs were extremely large or small. The distribution did not change significantly after excluding MICs estimated by less credible methods.ConclusionsThe size of the universally applicable MIC in SD units could not be determined. Anchor-based MICs in SD units were widely distributed, with more than half in the range of 0.2 to 0.8." @default.
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- W4207058677 date "2022-05-01" @default.
- W4207058677 modified "2023-10-17" @default.
- W4207058677 title "Minimal important changes in standard deviation units are highly variable and no universally applicable value can be determined" @default.
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- W4207058677 doi "https://doi.org/10.1016/j.jclinepi.2022.01.017" @default.
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