FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4207070208> ?p ?o ?g. }

• W4207070208 endingPage "814" @default.
• W4207070208 startingPage "799" @default.
• W4207070208 abstract "Alveolar echinococcosis is an epidemic disease caused by the parasitism of Echinococcus multilocularis (Em) larvae in the intermediate or final host.To identify and analyze B-cell and T-cell (Th1, Th2, and Th17) epitopes of the Em antigen protein thrombospondin 3 (TSP3).The amino acid sequence of TSP3 was obtained, and the secondary structural characteristics of TSP3 were predicted using bioinformatics software to further predict its potential T-cell and B-cell epitopes. The spleen lymphocytes of BALB/c mice, which were immunized with the TSP3 protein, were collected for co-culture with B-cell and T-cell antigen small peptides. The B-cell epitopes and T-cell epitope subtypes Th1, Th2, and Th17 were identified as having good immunogenicity.After identification, it was found that the predominant epitopes of B cells existing in TSP3 were T18-33, T45-55, and T110-122. Furthermore, the predominant epitopes of T cells existing in TSP3 were T33-42, T45-55, T80-90, and T110-122 in the T1 subtype, T45-55, T68-77, and T92-104 in the Th2 subtype, and T53-63 and T80-90 in the Th17 subtype.Six T-cell and eight B-cell dominant epitopes of the TSP3 antigen were revealed; these results may be applied in the development of a dominant epitope vaccine." @default.
• W4207070208 created "2022-01-26" @default.
• W4207070208 creator A5001475335 @default.
• W4207070208 creator A5002357780 @default.
• W4207070208 creator A5016725362 @default.
• W4207070208 creator A5020779815 @default.
• W4207070208 creator A5020860964 @default.
• W4207070208 creator A5026577079 @default.
• W4207070208 creator A5040809361 @default.
• W4207070208 creator A5057612778 @default.
• W4207070208 creator A5066235656 @default.
• W4207070208 creator A5075122427 @default.
• W4207070208 creator A5076052127 @default.
• W4207070208 creator A5077168746 @default.
• W4207070208 creator A5084486106 @default.
• W4207070208 date "2022-07-08" @default.
• W4207070208 modified "2023-09-26" @default.
• W4207070208 title "Prediction and identification of epitopes in the Echinococcus multilocularis thrombospondin 3 antigen" @default.
• W4207070208 cites W1537104679 @default.
• W4207070208 cites W2017926522 @default.
• W4207070208 cites W2023795898 @default.
• W4207070208 cites W2023887043 @default.
• W4207070208 cites W2035675215 @default.
• W4207070208 cites W2068659926 @default.
• W4207070208 cites W2071293410 @default.
• W4207070208 cites W2071315999 @default.
• W4207070208 cites W2105339394 @default.
• W4207070208 cites W2108654152 @default.
• W4207070208 cites W2110330032 @default.
• W4207070208 cites W2111051418 @default.
• W4207070208 cites W2112129368 @default.
• W4207070208 cites W2118817344 @default.
• W4207070208 cites W2353718907 @default.
• W4207070208 cites W2398952724 @default.
• W4207070208 cites W2406138888 @default.
• W4207070208 cites W2411752806 @default.
• W4207070208 cites W2482294854 @default.
• W4207070208 cites W2789510159 @default.
• W4207070208 cites W3001351676 @default.
• W4207070208 doi "https://doi.org/10.3233/thc-212983" @default.
• W4207070208 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35068426" @default.
• W4207070208 hasPublicationYear "2022" @default.
• W4207070208 type Work @default.
• W4207070208 citedByCount "2" @default.
• W4207070208 countsByYear W42070702082022 @default.
• W4207070208 crossrefType "journal-article" @default.
• W4207070208 hasAuthorship W4207070208A5001475335 @default.
• W4207070208 hasAuthorship W4207070208A5002357780 @default.
• W4207070208 hasAuthorship W4207070208A5016725362 @default.
• W4207070208 hasAuthorship W4207070208A5020779815 @default.
• W4207070208 hasAuthorship W4207070208A5020860964 @default.
• W4207070208 hasAuthorship W4207070208A5026577079 @default.
• W4207070208 hasAuthorship W4207070208A5040809361 @default.
• W4207070208 hasAuthorship W4207070208A5057612778 @default.
• W4207070208 hasAuthorship W4207070208A5066235656 @default.
• W4207070208 hasAuthorship W4207070208A5075122427 @default.
• W4207070208 hasAuthorship W4207070208A5076052127 @default.
• W4207070208 hasAuthorship W4207070208A5077168746 @default.
• W4207070208 hasAuthorship W4207070208A5084486106 @default.
• W4207070208 hasBestOaLocation W42070702081 @default.
• W4207070208 hasConcept C147483822 @default.
• W4207070208 hasConcept C153911025 @default.
• W4207070208 hasConcept C159047783 @default.
• W4207070208 hasConcept C195616568 @default.
• W4207070208 hasConcept C203014093 @default.
• W4207070208 hasConcept C2776090121 @default.
• W4207070208 hasConcept C2779687537 @default.
• W4207070208 hasConcept C2779752401 @default.
• W4207070208 hasConcept C2780868878 @default.
• W4207070208 hasConcept C86803240 @default.
• W4207070208 hasConcept C8891405 @default.
• W4207070208 hasConcept C90856448 @default.
• W4207070208 hasConceptScore W4207070208C147483822 @default.
• W4207070208 hasConceptScore W4207070208C153911025 @default.
• W4207070208 hasConceptScore W4207070208C159047783 @default.
• W4207070208 hasConceptScore W4207070208C195616568 @default.
• W4207070208 hasConceptScore W4207070208C203014093 @default.
• W4207070208 hasConceptScore W4207070208C2776090121 @default.
• W4207070208 hasConceptScore W4207070208C2779687537 @default.
• W4207070208 hasConceptScore W4207070208C2779752401 @default.
• W4207070208 hasConceptScore W4207070208C2780868878 @default.
• W4207070208 hasConceptScore W4207070208C86803240 @default.
• W4207070208 hasConceptScore W4207070208C8891405 @default.
• W4207070208 hasConceptScore W4207070208C90856448 @default.
• W4207070208 hasIssue "4" @default.
• W4207070208 hasLocation W42070702081 @default.
• W4207070208 hasLocation W42070702082 @default.
• W4207070208 hasLocation W42070702083 @default.
• W4207070208 hasOpenAccess W4207070208 @default.
• W4207070208 hasPrimaryLocation W42070702081 @default.
• W4207070208 hasRelatedWork W1519040467 @default.
• W4207070208 hasRelatedWork W1968665624 @default.
• W4207070208 hasRelatedWork W1974103061 @default.
• W4207070208 hasRelatedWork W1980095177 @default.
• W4207070208 hasRelatedWork W2039895504 @default.
• W4207070208 hasRelatedWork W2047171118 @default.
• W4207070208 hasRelatedWork W2120682552 @default.
• W4207070208 hasRelatedWork W2220102944 @default.

• next