FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4207073298> ?p ?o ?g. }

• W4207073298 endingPage "13" @default.
• W4207073298 startingPage "1" @default.
• W4207073298 abstract "Hypertension (HTN) is one of the most important risk factors for cardiovascular diseases. Despite advances in treatment and control of HTN, the prevalence of HTN is still increasing. MitoQ is a supplement that acts on mitochondria and attenuates reactive oxygen species (ROS), which plays an important role in cardiovascular health. miRNAs play an important role in the pathophysiology of HTN. We evaluated the effects of MitoQ supplementation and endurance training (ET), alone and in combination, on functional indices of the heart and serum levels of miR-126, miR-27a, antioxidants, and NO, in patients with HTN.In a double-blind randomized clinical trial, 52 male participants (age 40-55 years) were randomly divided into four groups (n = 13) of placebo, MitoQ (20 mg/day, oral), ET (cycle ergometer, moderate intensity, 40-60% VO2 peak, heart rate 120-140 b/min, 45 min a day, three days/week for six weeks), and MitoQ+ET. Cardiac function indices were assessed by echocardiography before and after interventions.Systolic blood pressure (SBP) significantly decreased in all intervention groups (P < 0.001) while DBP (P < 0.01) and LV hypertrophy (P < 0.05) were significantly decreased only in the MitoQ+ET group. Serum levels of SOD, GPx, and NO and the level of miR-126 significantly increased in all treatment groups, while miR-27a reduced in the ET (P < 0.05) and MitoQ+ET (P < 0.01) groups.Compared to MitoQ and ET alone, their combination has more prominent improving effects on cardiac health and amelioration of BP in the patients with HTN. These effects are through miR-126 and miR-27a modulation and ameliorating mitochondrial ROS production." @default.
• W4207073298 created "2022-01-26" @default.
• W4207073298 creator A5005392281 @default.
• W4207073298 creator A5012541098 @default.
• W4207073298 creator A5017194242 @default.
• W4207073298 creator A5027583327 @default.
• W4207073298 creator A5048826256 @default.
• W4207073298 creator A5072977063 @default.
• W4207073298 date "2022-01-13" @default.
• W4207073298 modified "2023-10-17" @default.
• W4207073298 title "Effect of Combined Endurance Training and MitoQ on Cardiac Function and Serum Level of Antioxidants, NO, miR-126, and miR-27a in Hypertensive Individuals" @default.
• W4207073298 cites W1501546025 @default.
• W4207073298 cites W1589918964 @default.
• W4207073298 cites W162468581 @default.
• W4207073298 cites W1864024909 @default.
• W4207073298 cites W2004008756 @default.
• W4207073298 cites W2018744300 @default.
• W4207073298 cites W2029795112 @default.
• W4207073298 cites W2033279061 @default.
• W4207073298 cites W2060965660 @default.
• W4207073298 cites W2061851373 @default.
• W4207073298 cites W2070151699 @default.
• W4207073298 cites W2079528051 @default.
• W4207073298 cites W2081452698 @default.
• W4207073298 cites W2082438956 @default.
• W4207073298 cites W2090819588 @default.
• W4207073298 cites W2098347568 @default.
• W4207073298 cites W2101064855 @default.
• W4207073298 cites W2101099004 @default.
• W4207073298 cites W2101518804 @default.
• W4207073298 cites W2103453396 @default.
• W4207073298 cites W2123051296 @default.
• W4207073298 cites W2123334275 @default.
• W4207073298 cites W2138407627 @default.
• W4207073298 cites W2138475105 @default.
• W4207073298 cites W2139594973 @default.
• W4207073298 cites W2317635756 @default.
• W4207073298 cites W2476546019 @default.
• W4207073298 cites W251715931 @default.
• W4207073298 cites W2535689509 @default.
• W4207073298 cites W2546088870 @default.
• W4207073298 cites W2555005209 @default.
• W4207073298 cites W2589996646 @default.
• W4207073298 cites W2592523887 @default.
• W4207073298 cites W2610988715 @default.
• W4207073298 cites W2744282338 @default.
• W4207073298 cites W2767187375 @default.
• W4207073298 cites W2789311455 @default.
• W4207073298 cites W2795462305 @default.
• W4207073298 cites W2796629168 @default.
• W4207073298 cites W2914843632 @default.
• W4207073298 cites W3084889611 @default.
• W4207073298 cites W3088654300 @default.
• W4207073298 cites W3166133234 @default.
• W4207073298 cites W73933502 @default.
• W4207073298 doi "https://doi.org/10.1155/2022/8720661" @default.
• W4207073298 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35071600" @default.
• W4207073298 hasPublicationYear "2022" @default.
• W4207073298 type Work @default.
• W4207073298 citedByCount "10" @default.
• W4207073298 countsByYear W42070732982022 @default.
• W4207073298 countsByYear W42070732982023 @default.
• W4207073298 crossrefType "journal-article" @default.
• W4207073298 hasAuthorship W4207073298A5005392281 @default.
• W4207073298 hasAuthorship W4207073298A5012541098 @default.
• W4207073298 hasAuthorship W4207073298A5017194242 @default.
• W4207073298 hasAuthorship W4207073298A5027583327 @default.
• W4207073298 hasAuthorship W4207073298A5048826256 @default.
• W4207073298 hasAuthorship W4207073298A5072977063 @default.
• W4207073298 hasBestOaLocation W42070732981 @default.
• W4207073298 hasConcept C111566952 @default.
• W4207073298 hasConcept C126322002 @default.
• W4207073298 hasConcept C142724271 @default.
• W4207073298 hasConcept C164705383 @default.
• W4207073298 hasConcept C204787440 @default.
• W4207073298 hasConcept C27081682 @default.
• W4207073298 hasConcept C2777953023 @default.
• W4207073298 hasConcept C2778198053 @default.
• W4207073298 hasConcept C71924100 @default.
• W4207073298 hasConcept C84393581 @default.
• W4207073298 hasConceptScore W4207073298C111566952 @default.
• W4207073298 hasConceptScore W4207073298C126322002 @default.
• W4207073298 hasConceptScore W4207073298C142724271 @default.
• W4207073298 hasConceptScore W4207073298C164705383 @default.
• W4207073298 hasConceptScore W4207073298C204787440 @default.
• W4207073298 hasConceptScore W4207073298C27081682 @default.
• W4207073298 hasConceptScore W4207073298C2777953023 @default.
• W4207073298 hasConceptScore W4207073298C2778198053 @default.
• W4207073298 hasConceptScore W4207073298C71924100 @default.
• W4207073298 hasConceptScore W4207073298C84393581 @default.
• W4207073298 hasLocation W42070732981 @default.
• W4207073298 hasLocation W42070732982 @default.
• W4207073298 hasLocation W42070732983 @default.
• W4207073298 hasLocation W42070732984 @default.
• W4207073298 hasOpenAccess W4207073298 @default.
• W4207073298 hasPrimaryLocation W42070732981 @default.
• W4207073298 hasRelatedWork W2013824670 @default.
• W4207073298 hasRelatedWork W2013890234 @default.

• next