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• W4207077188 endingPage "128260" @default.
• W4207077188 startingPage "128260" @default.
• W4207077188 abstract "The entrance of indium, an emerging contaminant from electronics, into the agroecosystem inevitably causes its accumulation in crops and raises exposure risk of humans via food chain. This study investigated indium uptake and toxicological effects in wheat plants under a worst-case scenario. Inhibition of root growth is a primary manifestation of indium toxicity and most absorbed indium accumulated in wheat roots with only a tiny portion reaching the leaves. The enhancement of reactive oxygen species (ROS), lipid peroxidation and protein oxidation in roots suggest that indium caused oxidative stress. Additionally, we found the levels of nitric oxide and peroxyinitrite, two major reactive nitrogen species (RNS), also increased in wheat roots under indium stress. These changes were accompanied by a raise in protein tyrosine nitration, thereby provoking nitrosative stress. The increase in peroxyinitrite and S-nitrosoglutathione content, S-nitrosoglutathione reductase activity as well as a concomitant reduction in glutathione concentrations suggest a rigorous metabolic interplay between ROS and RNS. Moreover, indium simultaneously triggered alteration in protein carbonylation and nitration. Overall, our results suggest that indium induced nitro-oxidative stress which probably contributes to toxicological effects in wheat plants, which are helpful in reducing the potential risk from emerging contaminants analogous to indium to humans." @default.
• W4207077188 created "2022-01-26" @default.
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• W4207077188 date "2022-04-01" @default.
• W4207077188 modified "2023-10-16" @default.
• W4207077188 title "Indium induces nitro-oxidative stress in roots of wheat (Triticum aestivum)" @default.
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• W4207077188 doi "https://doi.org/10.1016/j.jhazmat.2022.128260" @default.
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