FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4207078722> ?p ?o ?g. }

• W4207078722 abstract "Abstract Background Lean / Fat Free Body Mass (LBM) is metabolically involved in active processes such as resting energy expenditure, glucose uptake, and myokine secretion. Nonetheless, its association with insulin sensitivity / resistance / glucose tolerance and metabolic syndrome remains unclear in childhood. Methods The current investigation aimed to examine the differences in fat-free mass /lean body mass according to the presence of insulin sensitivity/insulin resistance/glucose tolerance/metabolic syndrome in children. A systematic search was carried out in Medline/PubMed, Embase, Scopus, Web of Science, and SciELO, covering the period from each database’s respective start to 21 June 2021. Two researchers evaluated 7111 studies according to the inclusion criteria: original human studies, written in English or Spanish, evaluating fat-free mass/lean body mass in children and adolescents including both with and without insulin sensitivity/insulin resistance /glucose tolerance and metabolic syndrome and reported the differences between them in terms of fat free mass/lean body mass. The results of the studies were combined with insulin sensitivity, insulin, resistance, glucose tolerance and metabolic syndrome. The standardized mean difference (SMD) in each study was calculated and combined using the random-effects model. Heterogeneity between studies was tested using the index of heterogeneity (I 2 ), leave-one-out sensitivity analyses were performed, and publication bias was assessed using the Egger and Begg tests. Results Finally, 15 studies which compared groups defined according to different glucose homeostasis criteria or metabolic syndrome out of 103 eligible studies were included in this systematic review and 12 studies in the meta-analysis. Meta-analysis showed lower fat-free mass/lean body mass percentage in participants with insulin resistance/glucose tolerance/metabolic syndrome (SMD -0.47; 95% CI, − 0.62 to − 0.32) while in mass units (kg), higher values were found in the same group (SMD, 1.01; 95% CI, 0.43 to 1.60). Conclusions Our results identified lower values of fat-free mass/lean body mass (%) in children and adolescents with insulin resistance/glucose tolerance/metabolic syndrome and higher values of fat-free mass/lean body mass when these are expressed in kg. The evidence of the impact of lean mass on children’s glucose homeostasis or metabolic syndrome is limited, so future studies research should focus on explaining the effect of fat-free mass/lean body mass on different metabolic outcomes. Moreover, it may be interesting to evaluate the quality (muscle density) or functional (muscle strength) outcomes in addition to both absolute (kg) and relative (%) values in future studies. The systematic review was prospectively registered at PROSPERO (registration number CRD42019124734; available at: http://www.crd.york.ac.uk/prospero [accessed: 05 April 2019])." @default.
• W4207078722 created "2022-01-26" @default.
• W4207078722 creator A5031848495 @default.
• W4207078722 creator A5032803048 @default.
• W4207078722 creator A5044173909 @default.
• W4207078722 creator A5045763343 @default.
• W4207078722 creator A5051231184 @default.
• W4207078722 creator A5060104573 @default.
• W4207078722 creator A5089654160 @default.
• W4207078722 date "2022-01-22" @default.
• W4207078722 modified "2023-10-16" @default.
• W4207078722 title "Fat-free/lean body mass in children with insulin resistance or metabolic syndrome: a systematic review and meta-analysis" @default.
• W4207078722 cites W1519785014 @default.
• W4207078722 cites W1576436451 @default.
• W4207078722 cites W18381781 @default.
• W4207078722 cites W1854801150 @default.
• W4207078722 cites W1963956753 @default.
• W4207078722 cites W1964435302 @default.
• W4207078722 cites W1964913907 @default.
• W4207078722 cites W1969689660 @default.
• W4207078722 cites W1974854718 @default.
• W4207078722 cites W1982651577 @default.
• W4207078722 cites W1985533068 @default.
• W4207078722 cites W1992237951 @default.
• W4207078722 cites W1995865969 @default.
• W4207078722 cites W1996835915 @default.
• W4207078722 cites W1998552927 @default.
• W4207078722 cites W2004531608 @default.
• W4207078722 cites W2008283534 @default.
• W4207078722 cites W2012933128 @default.
• W4207078722 cites W2015939969 @default.
• W4207078722 cites W2018492975 @default.
• W4207078722 cites W2026963592 @default.
• W4207078722 cites W2030539348 @default.
• W4207078722 cites W2041293830 @default.
• W4207078722 cites W2045078825 @default.
• W4207078722 cites W2059209925 @default.
• W4207078722 cites W2062030000 @default.
• W4207078722 cites W2064099715 @default.
• W4207078722 cites W2064416255 @default.
• W4207078722 cites W2070030549 @default.
• W4207078722 cites W2072396023 @default.
• W4207078722 cites W2072489391 @default.
• W4207078722 cites W2072910410 @default.
• W4207078722 cites W2082925862 @default.
• W4207078722 cites W2091512839 @default.
• W4207078722 cites W2094954377 @default.
• W4207078722 cites W2095068198 @default.
• W4207078722 cites W2095591618 @default.
• W4207078722 cites W2096914907 @default.
• W4207078722 cites W2097692855 @default.
• W4207078722 cites W2098548679 @default.
• W4207078722 cites W2098923148 @default.
• W4207078722 cites W2103520707 @default.
• W4207078722 cites W2104754537 @default.
• W4207078722 cites W2106221382 @default.
• W4207078722 cites W2108666010 @default.
• W4207078722 cites W2109026577 @default.
• W4207078722 cites W2109348533 @default.
• W4207078722 cites W2112059828 @default.
• W4207078722 cites W2122901152 @default.
• W4207078722 cites W2125435699 @default.
• W4207078722 cites W2126545477 @default.
• W4207078722 cites W2134833483 @default.
• W4207078722 cites W2134852288 @default.
• W4207078722 cites W2134909077 @default.
• W4207078722 cites W2136121411 @default.
• W4207078722 cites W2138199338 @default.
• W4207078722 cites W2141555509 @default.
• W4207078722 cites W2143272612 @default.
• W4207078722 cites W2144428490 @default.
• W4207078722 cites W2144456954 @default.
• W4207078722 cites W2145501994 @default.
• W4207078722 cites W2145731761 @default.
• W4207078722 cites W2149751887 @default.
• W4207078722 cites W2153849900 @default.
• W4207078722 cites W2156313507 @default.
• W4207078722 cites W2167185652 @default.
• W4207078722 cites W2169205464 @default.
• W4207078722 cites W2170892587 @default.
• W4207078722 cites W2171039948 @default.
• W4207078722 cites W2282977616 @default.
• W4207078722 cites W2299177375 @default.
• W4207078722 cites W2314117820 @default.
• W4207078722 cites W2343927668 @default.
• W4207078722 cites W2471940872 @default.
• W4207078722 cites W2514859791 @default.
• W4207078722 cites W2518455214 @default.
• W4207078722 cites W2548033079 @default.
• W4207078722 cites W2567362164 @default.
• W4207078722 cites W2585060736 @default.
• W4207078722 cites W2588681363 @default.
• W4207078722 cites W2736374687 @default.
• W4207078722 cites W2754571660 @default.
• W4207078722 cites W2788777662 @default.
• W4207078722 cites W2808591059 @default.
• W4207078722 cites W2873555251 @default.
• W4207078722 cites W2888940391 @default.
• W4207078722 cites W2891363291 @default.
• W4207078722 cites W2892310420 @default.

• next