Matches in SemOpenAlex for { <https://semopenalex.org/work/W4207086475> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W4207086475 endingPage "22" @default.
- W4207086475 startingPage "14" @default.
- W4207086475 abstract "Monoclonal antibodies (mAbs) are increasingly being prescribed to patients and investigated in the field of medicine and research. This class of medication is unique due to its ability to be engineered into targeting a specific receptor. Numerous studies and reviews have reported the efficacy, potency, and clinical usage of mAbs in the treatment of a variety of diseases ranging from autoimmune disorders to malignant cancers. However, very few publications classify and provide a brief synopsis of mAbs that includes their pharmacological profiles. mechanisms of action, uses, and side effects in a concise manner. Therefore, this review aims to classify the current mAbs drugs used in clinical practice according to system diseases by providing a brief summary for each of them. For example, regarding cardiovascular disorders, mAbs such as Abciximab, Bevacizumab, and Digoxin Immune Fab will be reviewed. Denosumab, used to treat musculoskeletal disorders, will be also discussed. In addition, mAbs such as Adalimumab, Eculizumab, Natalizumab used in autoimmune disorders and Alemtuzumab, Trastuzumab, Cetuximab, and Rituximab that are prescribed for tumors will be reviewed. Finally, we shall discuss two mAbs that are IL-6 antagonists, Tocilizumab and Siltuximab, which are in ongoing clinical trials as potential treatments of COVID-19. The mAbs have profound benefits against chronic and malignant conditions, and the overall purpose of this review is to illustrate the basic pharmacological profiles of mAbs that physicians may find useful in establishing their management protocols." @default.
- W4207086475 created "2022-01-26" @default.
- W4207086475 creator A5011621199 @default.
- W4207086475 creator A5029594290 @default.
- W4207086475 creator A5074754174 @default.
- W4207086475 creator A5088032785 @default.
- W4207086475 date "2021-11-01" @default.
- W4207086475 modified "2023-09-29" @default.
- W4207086475 title "A BRIEF SYNOPSIS OF MONOCLONAL ANTIBODY FOR THE TREATMENT OF VARIOUS GROUPS OF DISEASES." @default.
- W4207086475 cites W2087764276 @default.
- W4207086475 cites W2155934675 @default.
- W4207086475 cites W2169031812 @default.
- W4207086475 cites W2417465198 @default.
- W4207086475 cites W2691302834 @default.
- W4207086475 cites W2736093189 @default.
- W4207086475 cites W2760907988 @default.
- W4207086475 cites W2891193646 @default.
- W4207086475 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35071113" @default.
- W4207086475 hasPublicationYear "2021" @default.
- W4207086475 type Work @default.
- W4207086475 citedByCount "0" @default.
- W4207086475 crossrefType "journal-article" @default.
- W4207086475 hasAuthorship W4207086475A5011621199 @default.
- W4207086475 hasAuthorship W4207086475A5029594290 @default.
- W4207086475 hasAuthorship W4207086475A5074754174 @default.
- W4207086475 hasAuthorship W4207086475A5088032785 @default.
- W4207086475 hasConcept C111684460 @default.
- W4207086475 hasConcept C126322002 @default.
- W4207086475 hasConcept C143998085 @default.
- W4207086475 hasConcept C159654299 @default.
- W4207086475 hasConcept C177713679 @default.
- W4207086475 hasConcept C203014093 @default.
- W4207086475 hasConcept C2776694085 @default.
- W4207086475 hasConcept C2777178219 @default.
- W4207086475 hasConcept C2777575956 @default.
- W4207086475 hasConcept C2777802072 @default.
- W4207086475 hasConcept C2777991916 @default.
- W4207086475 hasConcept C2779015954 @default.
- W4207086475 hasConcept C2779998722 @default.
- W4207086475 hasConcept C2780132546 @default.
- W4207086475 hasConcept C2780640218 @default.
- W4207086475 hasConcept C2780653079 @default.
- W4207086475 hasConcept C2781004633 @default.
- W4207086475 hasConcept C535046627 @default.
- W4207086475 hasConcept C542903549 @default.
- W4207086475 hasConcept C71924100 @default.
- W4207086475 hasConcept C98274493 @default.
- W4207086475 hasConceptScore W4207086475C111684460 @default.
- W4207086475 hasConceptScore W4207086475C126322002 @default.
- W4207086475 hasConceptScore W4207086475C143998085 @default.
- W4207086475 hasConceptScore W4207086475C159654299 @default.
- W4207086475 hasConceptScore W4207086475C177713679 @default.
- W4207086475 hasConceptScore W4207086475C203014093 @default.
- W4207086475 hasConceptScore W4207086475C2776694085 @default.
- W4207086475 hasConceptScore W4207086475C2777178219 @default.
- W4207086475 hasConceptScore W4207086475C2777575956 @default.
- W4207086475 hasConceptScore W4207086475C2777802072 @default.
- W4207086475 hasConceptScore W4207086475C2777991916 @default.
- W4207086475 hasConceptScore W4207086475C2779015954 @default.
- W4207086475 hasConceptScore W4207086475C2779998722 @default.
- W4207086475 hasConceptScore W4207086475C2780132546 @default.
- W4207086475 hasConceptScore W4207086475C2780640218 @default.
- W4207086475 hasConceptScore W4207086475C2780653079 @default.
- W4207086475 hasConceptScore W4207086475C2781004633 @default.
- W4207086475 hasConceptScore W4207086475C535046627 @default.
- W4207086475 hasConceptScore W4207086475C542903549 @default.
- W4207086475 hasConceptScore W4207086475C71924100 @default.
- W4207086475 hasConceptScore W4207086475C98274493 @default.
- W4207086475 hasIssue "11" @default.
- W4207086475 hasLocation W42070864751 @default.
- W4207086475 hasOpenAccess W4207086475 @default.
- W4207086475 hasPrimaryLocation W42070864751 @default.
- W4207086475 hasRelatedWork W11739056 @default.
- W4207086475 hasRelatedWork W13154270 @default.
- W4207086475 hasRelatedWork W14196901 @default.
- W4207086475 hasRelatedWork W16425881 @default.
- W4207086475 hasRelatedWork W19152528 @default.
- W4207086475 hasRelatedWork W3648864 @default.
- W4207086475 hasRelatedWork W4507633 @default.
- W4207086475 hasRelatedWork W5842072 @default.
- W4207086475 hasRelatedWork W6187537 @default.
- W4207086475 hasRelatedWork W6817586 @default.
- W4207086475 hasVolume "10" @default.
- W4207086475 isParatext "false" @default.
- W4207086475 isRetracted "false" @default.
- W4207086475 workType "article" @default.