Matches in SemOpenAlex for { <https://semopenalex.org/work/W4210247907> ?p ?o ?g. }
- W4210247907 endingPage "696" @default.
- W4210247907 startingPage "696" @default.
- W4210247907 abstract "(1) Background: Prostate cancer is the most common cancer in men and can be treated with radical prostatectomy (RPE) or radiotherapy in the primary setting. Stereotactic radiotherapy (SBRT) has proven to be effective and well tolerated in this setting. However, if SBRT is an equally promising treatment option if applied in the adjuvant or salvage setting after RPE remains unknown. (2) Methods: We searched the PubMed and Embase databases with the following full-text queries in August 2021 for any combination of the terms SBRT, prostate, adjuvant, postoperative, salvage, stereotactic radiotherapy, prostate bed. There were no limitations regarding publication date or language. We adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations. (3) Results: We identified 11 individual studies that were included in this systematic review. Three publications included patients without prior radiotherapy and the remaining eight patients with prior radiotherapy. In all but two publications the radiation target was the macroscopic recurrence. SBRT was overall well tolerated with acceptable rates of acute and late gastrointestinal or genitourinary toxicity. Quality of life was published for two phase I trials with good results. There was a very heterogeneous reporting on biochemical control after SBRT. (4) Conclusions: At this point, ultra-hypofractionated RT using SBRT to the prostate bed remains experimental and its use should be restricted to clinical trials. Given the biological rationale for extreme hypofractionation in patients with prostate cancer and the acceptable toxicity rates that have been reported, further exploration of this field is warranted." @default.
- W4210247907 created "2022-02-08" @default.
- W4210247907 creator A5026826746 @default.
- W4210247907 creator A5029096168 @default.
- W4210247907 creator A5042220969 @default.
- W4210247907 creator A5049692975 @default.
- W4210247907 creator A5053516632 @default.
- W4210247907 creator A5061995639 @default.
- W4210247907 creator A5072432694 @default.
- W4210247907 creator A5075679674 @default.
- W4210247907 creator A5084335427 @default.
- W4210247907 creator A5085718013 @default.
- W4210247907 creator A5090537777 @default.
- W4210247907 date "2022-01-29" @default.
- W4210247907 modified "2023-10-01" @default.
- W4210247907 title "Stereotactic Radiotherapy after Radical Prostatectomy in Patients with Prostate Cancer in the Adjuvant or Salvage Setting: A Systematic Review" @default.
- W4210247907 cites W1503328597 @default.
- W4210247907 cites W1525266506 @default.
- W4210247907 cites W1572319397 @default.
- W4210247907 cites W1749926766 @default.
- W4210247907 cites W1772827770 @default.
- W4210247907 cites W1885969965 @default.
- W4210247907 cites W1970324515 @default.
- W4210247907 cites W1980601718 @default.
- W4210247907 cites W1983228790 @default.
- W4210247907 cites W1990434297 @default.
- W4210247907 cites W1996452074 @default.
- W4210247907 cites W1998994416 @default.
- W4210247907 cites W1999909534 @default.
- W4210247907 cites W2004229786 @default.
- W4210247907 cites W2010318012 @default.
- W4210247907 cites W2016238862 @default.
- W4210247907 cites W2022226163 @default.
- W4210247907 cites W2026641917 @default.
- W4210247907 cites W2039139527 @default.
- W4210247907 cites W2040659915 @default.
- W4210247907 cites W2054976917 @default.
- W4210247907 cites W2058476300 @default.
- W4210247907 cites W2064420048 @default.
- W4210247907 cites W2065120151 @default.
- W4210247907 cites W2069515467 @default.
- W4210247907 cites W2088212219 @default.
- W4210247907 cites W2091411464 @default.
- W4210247907 cites W2097228107 @default.
- W4210247907 cites W2101889062 @default.
- W4210247907 cites W2115587111 @default.
- W4210247907 cites W2116691961 @default.
- W4210247907 cites W2127707619 @default.
- W4210247907 cites W2130514725 @default.
- W4210247907 cites W2137282952 @default.
- W4210247907 cites W2137283235 @default.
- W4210247907 cites W2140754632 @default.
- W4210247907 cites W2152529149 @default.
- W4210247907 cites W2156306108 @default.
- W4210247907 cites W2156399381 @default.
- W4210247907 cites W2161462871 @default.
- W4210247907 cites W2164748078 @default.
- W4210247907 cites W2253196302 @default.
- W4210247907 cites W2277911383 @default.
- W4210247907 cites W2278230463 @default.
- W4210247907 cites W2431449819 @default.
- W4210247907 cites W2470797207 @default.
- W4210247907 cites W2475048914 @default.
- W4210247907 cites W2487033212 @default.
- W4210247907 cites W2510755861 @default.
- W4210247907 cites W2523396458 @default.
- W4210247907 cites W2586176133 @default.
- W4210247907 cites W2587523334 @default.
- W4210247907 cites W2770633848 @default.
- W4210247907 cites W2771347394 @default.
- W4210247907 cites W2791322512 @default.
- W4210247907 cites W2793213548 @default.
- W4210247907 cites W2805446191 @default.
- W4210247907 cites W2899015261 @default.
- W4210247907 cites W2913674115 @default.
- W4210247907 cites W2915526116 @default.
- W4210247907 cites W2928985222 @default.
- W4210247907 cites W2951403714 @default.
- W4210247907 cites W2952903287 @default.
- W4210247907 cites W2962556688 @default.
- W4210247907 cites W2964049385 @default.
- W4210247907 cites W2967858919 @default.
- W4210247907 cites W2973514824 @default.
- W4210247907 cites W2980439634 @default.
- W4210247907 cites W2988253605 @default.
- W4210247907 cites W2993539218 @default.
- W4210247907 cites W3003111479 @default.
- W4210247907 cites W3011586574 @default.
- W4210247907 cites W3025314506 @default.
- W4210247907 cites W3087977689 @default.
- W4210247907 cites W3088103374 @default.
- W4210247907 cites W3088359655 @default.
- W4210247907 cites W3088633614 @default.
- W4210247907 cites W3108817006 @default.
- W4210247907 cites W3118166616 @default.
- W4210247907 cites W3118615836 @default.
- W4210247907 cites W3133468505 @default.
- W4210247907 cites W3168815344 @default.