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- W4210260015 abstract "Transposable elements (TEs) are mobile, repetitive DNA sequences that make the largest contribution to genome bulk. They thus contribute to the so-called “dark matter of the genome”, the part of the genome in which nothing is immediately recognizable as biologically functional. We developed a new method, based on k-mers, to identify degenerate TE sequences. With this new algorithm, we detect up to 10% of the A. thaliana genome as derived from as yet unidentified TEs, bringing the proportion of the genome known to be derived from TEs up to 50%. A significant proportion of these sequences overlapped conserved non-coding sequences identified in crucifers and rosids, and transcription factor binding sites. They are overrepresented in some gene regulation networks, such as the flowering gene network, suggesting a functional role for these sequences that have been conserved for more than 100 million years, since the spread of flowering plants in the Cretaceous." @default.
- W4210260015 created "2022-02-08" @default.
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- W4210260015 date "2022-02-04" @default.
- W4210260015 modified "2023-10-14" @default.
- W4210260015 title "Traces of transposable elements in genome dark matter co-opted by flowering gene regulation networks" @default.
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- W4210260015 doi "https://doi.org/10.24072/pcjournal.68" @default.
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