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- W4210271097 abstract "Eosinophilic esophagitis (EoE) is an immune-mediated chronic inflammatory disorder that, in most children and many adults, is triggered by food antigens. In 1995, Kelly et al. first described EoE in children and also demonstrated that clinical symptoms and eosinophilic esophageal inflammation was reversed with exclusive amino acid-based elemental diet and exclusion of all food antigens. The authors also identified specific food antigens including cow’s milk, soy, wheat, egg, and peanuts as potential proteins that induced the esophageal inflammation. These initial important observations from that first pediatric study form the basis of the different dietary approaches currently offered to treat EoE. The dietary approach is based on the hypothesis that food antigens trigger eosinophilic inflammation, and clinical along with histological remission can be induced by identifying and excluding the causative food antigens. It is believed that eliminating causative food antigens targets the cause and thus induces long-term remission. There are no prospective controlled double-blind studies assessing and demonstrating the efficacy of the different dietary approaches. The current recommendation for treatment of EoE with diet is based on a number of retrospective and observational studies. The available dietary approaches include: (1) elemental diet with an amino acid-based complete liquid formulation, (2) directed elimination diet based on the results of allergy testing, and (3) standard or nondirected elimination diet where a number of common food antigens are excluded from the diet. The type of treatment selected should be individualized and tailored to the needs of the patient and should depend on the presence or lack of anaphylactic food allergies, the age of the child, and the comfort and acceptance of the elimination diet by the family." @default.
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- W4210271097 date "2011-08-20" @default.
- W4210271097 modified "2023-10-18" @default.
- W4210271097 title "Dietary Treatment of Eosinophilic Esophagitis" @default.
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- W4210271097 doi "https://doi.org/10.1007/978-1-60761-515-6_24" @default.
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