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- W4210272013 abstract "We thank the respondents to our article 1 Lin TL, Wu CY, Yen JJ, et al. Fracture risks in patients with atopic dermatitis: a nationwide matched cohort study [e-pub ahead of print]. Ann Allergy Asthma Immunol. doi:10.1016/j.anai.2021.09.004. Accessed September 17, 2021. Google Scholar for their insightful comments. Although we have matched subjects in both cohorts by age, sex, comorbidities, and index date, Lin et al 2 Lin YP, Lee YT, Lee YH, Wei CC. Comment on Fracture risks in patients with atopic dermatitis: a nationwide matched cohort study. Ann Allergy Asthma Immunol. Google Scholar indicate a lack of adjustment for co-medication status, including the use of corticosteroids and disease-modifying antirheumatic drugs (DMARDs), in the propensity score. We agree that these medications are important confounders on fracture. We therefore had conducted multivariate analysis in the published article by adjustment for corticosteroids, DMARDs, and phototherapy. Moderate to severe atopic dermatitis (AD) was found to be associated with fractures, independent of exposure to these treatments. Further sensitivity analyses stratified by pharmacologic treatment and phototherapy revealed consistent results. Comment on fracture risks in patients with atopic dermatitis: A nationwide matched cohort studyAnnals of Allergy, Asthma & ImmunologyVol. 128Issue 2PreviewWe read with great interest the article by Lin et al1 reporting the association of incidental fractures in patients with atopic dermatitis (AD). We appreciate the authors who collected data from Taiwan's National Health Insurance Research Database and conducted a great cohort study. Nevertheless, we highlight some key points. Full-Text PDF Fracture risks in patients with atopic dermatitis: A nationwide matched cohort studyAnnals of Allergy, Asthma & ImmunologyVol. 127Issue 6PreviewThe risk of osteoporosis has been explored in atopic dermatitis (AD). The long-term risk of fractures in patients with AD and the effects of various AD treatments on bone health remain to be elucidated. Full-Text PDF" @default.
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- W4210272013 date "2022-02-01" @default.
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- W4210272013 title "Fracture risks in patients with atopic dermatitis" @default.
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- W4210272013 doi "https://doi.org/10.1016/j.anai.2021.11.001" @default.
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