FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4210296412> ?p ?o ?g. }

• W4210296412 endingPage "100817" @default.
• W4210296412 startingPage "100817" @default.
• W4210296412 abstract "The rapid and reliable detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroconversion in humans is crucial for suitable infection control. In this sense, many studies have focused on increasing the sensibility, lowering the detection limits and minimizing false negative/positive results. Thus, biosensors based on nanoarchitectures of conducting polymers are promising alternatives to more traditional materials since they can hold improved surface area, higher electrical conductivity and electrochemical activity. In this work, we reported the analytical comparison of two different conducting polymers morphologies for the development of an impedimetric biosensor to monitor SARS-CoV-2 seroconversion in humans. Biosensors based on polypyrrole (PPy), synthesized in both globular and nanotubular (NT) morphology, and gold nanoparticles are reported, using a self-assembly monolayer of 3-mercaptopropionic acid and covalently linked SARS-CoV-2 Nucleocapsid protein. First, the novel hybrid materials were characterized by electron microscopy and electrochemical measurements, and the biosensor step-by-step construction was characterized by electrochemical and spectroscopic techniques. As a proof of concept, the biosensor was used for the impedimetric detection of anti-SARS-CoV-2 Nucleocapsid protein monoclonal antibodies. The results showed a linear response for different antibody concentrations, good sensibility and possibility to quantify 7.442 and 0.4 ng/mL of monoclonal antibody for PPy in the globular and NT morphology, respectively. The PPy-NTs biosensor was able to discriminate serum obtained from COVID-19 positive versus negative clinical samples and is a promising tool for COVID-19 immunodiagnostic, which can contribute to further studies concerning rapid, efficient, and reliable detections." @default.
• W4210296412 created "2022-02-08" @default.
• W4210296412 creator A5011922257 @default.
• W4210296412 creator A5020658146 @default.
• W4210296412 creator A5028001897 @default.
• W4210296412 creator A5028104218 @default.
• W4210296412 creator A5038515185 @default.
• W4210296412 creator A5045499827 @default.
• W4210296412 creator A5064269560 @default.
• W4210296412 creator A5069284557 @default.
• W4210296412 creator A5071752190 @default.
• W4210296412 creator A5078791861 @default.
• W4210296412 creator A5086646522 @default.
• W4210296412 creator A5086824480 @default.
• W4210296412 creator A5091132537 @default.
• W4210296412 date "2022-06-01" @default.
• W4210296412 modified "2023-10-18" @default.
• W4210296412 title "Development of polypyrrole (nano)structures decorated with gold nanoparticles toward immunosensing for COVID-19 serological diagnosis" @default.
• W4210296412 cites W1463701503 @default.
• W4210296412 cites W1898129882 @default.
• W4210296412 cites W1972666377 @default.
• W4210296412 cites W1975975754 @default.
• W4210296412 cites W1982202764 @default.
• W4210296412 cites W1994522620 @default.
• W4210296412 cites W1999737291 @default.
• W4210296412 cites W2001571793 @default.
• W4210296412 cites W2009094876 @default.
• W4210296412 cites W2016042146 @default.
• W4210296412 cites W2025884294 @default.
• W4210296412 cites W2046311974 @default.
• W4210296412 cites W2053564208 @default.
• W4210296412 cites W2056084870 @default.
• W4210296412 cites W2083797409 @default.
• W4210296412 cites W2110938859 @default.
• W4210296412 cites W2136019705 @default.
• W4210296412 cites W2138050878 @default.
• W4210296412 cites W2150644551 @default.
• W4210296412 cites W2160254346 @default.
• W4210296412 cites W2166806803 @default.
• W4210296412 cites W2168700040 @default.
• W4210296412 cites W2494856402 @default.
• W4210296412 cites W2510868957 @default.
• W4210296412 cites W2760258398 @default.
• W4210296412 cites W2782561501 @default.
• W4210296412 cites W2792466472 @default.
• W4210296412 cites W2792682065 @default.
• W4210296412 cites W2896576254 @default.
• W4210296412 cites W2912474350 @default.
• W4210296412 cites W2970823211 @default.
• W4210296412 cites W3008827533 @default.
• W4210296412 cites W3011203658 @default.
• W4210296412 cites W3015544413 @default.
• W4210296412 cites W3023276205 @default.
• W4210296412 cites W3029841422 @default.
• W4210296412 cites W3038899423 @default.
• W4210296412 cites W3045973528 @default.
• W4210296412 cites W3091281260 @default.
• W4210296412 cites W3092145882 @default.
• W4210296412 cites W3094064847 @default.
• W4210296412 cites W3111314177 @default.
• W4210296412 cites W3125933764 @default.
• W4210296412 cites W3126653450 @default.
• W4210296412 cites W3135844655 @default.
• W4210296412 cites W3137559790 @default.
• W4210296412 cites W3138783217 @default.
• W4210296412 cites W3161145943 @default.
• W4210296412 cites W3167454123 @default.
• W4210296412 cites W3173583905 @default.
• W4210296412 cites W3183144592 @default.
• W4210296412 cites W3189460572 @default.
• W4210296412 cites W3199388016 @default.
• W4210296412 cites W832321972 @default.
• W4210296412 doi "https://doi.org/10.1016/j.mtchem.2022.100817" @default.
• W4210296412 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35155879" @default.
• W4210296412 hasPublicationYear "2022" @default.
• W4210296412 type Work @default.
• W4210296412 citedByCount "21" @default.
• W4210296412 countsByYear W42102964122022 @default.
• W4210296412 countsByYear W42102964122023 @default.
• W4210296412 crossrefType "journal-article" @default.
• W4210296412 hasAuthorship W4210296412A5011922257 @default.
• W4210296412 hasAuthorship W4210296412A5020658146 @default.
• W4210296412 hasAuthorship W4210296412A5028001897 @default.
• W4210296412 hasAuthorship W4210296412A5028104218 @default.
• W4210296412 hasAuthorship W4210296412A5038515185 @default.
• W4210296412 hasAuthorship W4210296412A5045499827 @default.
• W4210296412 hasAuthorship W4210296412A5064269560 @default.
• W4210296412 hasAuthorship W4210296412A5069284557 @default.
• W4210296412 hasAuthorship W4210296412A5071752190 @default.
• W4210296412 hasAuthorship W4210296412A5078791861 @default.
• W4210296412 hasAuthorship W4210296412A5086646522 @default.
• W4210296412 hasAuthorship W4210296412A5086824480 @default.
• W4210296412 hasAuthorship W4210296412A5091132537 @default.
• W4210296412 hasBestOaLocation W42102964122 @default.
• W4210296412 hasConcept C104819515 @default.
• W4210296412 hasConcept C128972844 @default.
• W4210296412 hasConcept C133495861 @default.
• W4210296412 hasConcept C153911025 @default.

• next