Matches in SemOpenAlex for { <https://semopenalex.org/work/W4210297789> ?p ?o ?g. }
- W4210297789 endingPage "101172" @default.
- W4210297789 startingPage "101172" @default.
- W4210297789 abstract "Bone microarchitecture is an important component of bone quality and disturbances may reduce bone strength and resistance to trauma. Kidney transplant recipients have an excess risk of fractures, and bone loss affecting both trabecular and cortical bone compartments have been demonstrated after kidney transplantation. The primary aim of this study was to investigate the impact of kidney transplantation on trabecular and cortical bone microarchitecture, assessed by histomorphometry and micro computed tomography (μCT). Iliac crest bone biopsies, analyzed by bone histomorphometry and μCT, were performed at time of kidney transplantation and 12 months post-transplantation in an unselected cohort of 30 patients. Biochemical markers of mineral metabolism and bone turnover were measured at both time-points. At 12 months post-transplantation, bone turnover was low in 5 (17%) and normal in 25 (83%) patients. By histomorphometry, bone remodeling normalized, with decreases in eroded perimeters (4.0 to 2.1%, p = 0.02) and number of patients with marrow fibrosis (41 to 0%, p < 0.001). By μCT, trabecular thickness (134 to 125 μM, p = 0.003) decreased slightly. Other parameters of bone volume and microarchitecture, including cortical thickness (729 to 713 μm, p = 0.73) and porosity (10.2 to 9.5%, p = 0.15), remained stable. We conclude that kidney transplantation with current immunosuppressive protocols has a limited impact on bone microarchitecture." @default.
- W4210297789 created "2022-02-08" @default.
- W4210297789 creator A5001830310 @default.
- W4210297789 creator A5006334937 @default.
- W4210297789 creator A5007986643 @default.
- W4210297789 creator A5070423452 @default.
- W4210297789 creator A5077350979 @default.
- W4210297789 creator A5083782401 @default.
- W4210297789 creator A5086582769 @default.
- W4210297789 creator A5088776624 @default.
- W4210297789 date "2022-06-01" @default.
- W4210297789 modified "2023-10-13" @default.
- W4210297789 title "Contemporary kidney transplantation has a limited impact on bone microarchitecture" @default.
- W4210297789 cites W1495552042 @default.
- W4210297789 cites W1543460749 @default.
- W4210297789 cites W1587241510 @default.
- W4210297789 cites W1959989187 @default.
- W4210297789 cites W1961671882 @default.
- W4210297789 cites W1973511139 @default.
- W4210297789 cites W1992836905 @default.
- W4210297789 cites W2006753445 @default.
- W4210297789 cites W2033875033 @default.
- W4210297789 cites W2034468185 @default.
- W4210297789 cites W2039395975 @default.
- W4210297789 cites W2045259447 @default.
- W4210297789 cites W2071419543 @default.
- W4210297789 cites W2071473766 @default.
- W4210297789 cites W2096425957 @default.
- W4210297789 cites W2118625269 @default.
- W4210297789 cites W2162154153 @default.
- W4210297789 cites W2162942364 @default.
- W4210297789 cites W2165084323 @default.
- W4210297789 cites W2169027518 @default.
- W4210297789 cites W2171245455 @default.
- W4210297789 cites W2295854137 @default.
- W4210297789 cites W2311866482 @default.
- W4210297789 cites W2313649741 @default.
- W4210297789 cites W2316799303 @default.
- W4210297789 cites W2411081135 @default.
- W4210297789 cites W2544291754 @default.
- W4210297789 cites W2563122911 @default.
- W4210297789 cites W2588935929 @default.
- W4210297789 cites W2763858238 @default.
- W4210297789 cites W2792154527 @default.
- W4210297789 cites W2794349658 @default.
- W4210297789 cites W2803182829 @default.
- W4210297789 cites W2896938201 @default.
- W4210297789 cites W2906847003 @default.
- W4210297789 cites W2919257902 @default.
- W4210297789 cites W2945374807 @default.
- W4210297789 cites W3015204213 @default.
- W4210297789 cites W3081633604 @default.
- W4210297789 cites W3166405803 @default.
- W4210297789 cites W3168525435 @default.
- W4210297789 cites W4211140718 @default.
- W4210297789 doi "https://doi.org/10.1016/j.bonr.2022.101172" @default.
- W4210297789 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35198658" @default.
- W4210297789 hasPublicationYear "2022" @default.
- W4210297789 type Work @default.
- W4210297789 citedByCount "2" @default.
- W4210297789 countsByYear W42102977892023 @default.
- W4210297789 crossrefType "journal-article" @default.
- W4210297789 hasAuthorship W4210297789A5001830310 @default.
- W4210297789 hasAuthorship W4210297789A5006334937 @default.
- W4210297789 hasAuthorship W4210297789A5007986643 @default.
- W4210297789 hasAuthorship W4210297789A5070423452 @default.
- W4210297789 hasAuthorship W4210297789A5077350979 @default.
- W4210297789 hasAuthorship W4210297789A5083782401 @default.
- W4210297789 hasAuthorship W4210297789A5086582769 @default.
- W4210297789 hasAuthorship W4210297789A5088776624 @default.
- W4210297789 hasBestOaLocation W42102977891 @default.
- W4210297789 hasConcept C126322002 @default.
- W4210297789 hasConcept C126894567 @default.
- W4210297789 hasConcept C141071460 @default.
- W4210297789 hasConcept C142724271 @default.
- W4210297789 hasConcept C170033053 @default.
- W4210297789 hasConcept C2776541429 @default.
- W4210297789 hasConcept C2776886416 @default.
- W4210297789 hasConcept C2779079599 @default.
- W4210297789 hasConcept C2780091579 @default.
- W4210297789 hasConcept C2780303639 @default.
- W4210297789 hasConcept C2781451080 @default.
- W4210297789 hasConcept C2909674915 @default.
- W4210297789 hasConcept C2911091166 @default.
- W4210297789 hasConcept C3018268312 @default.
- W4210297789 hasConcept C71924100 @default.
- W4210297789 hasConceptScore W4210297789C126322002 @default.
- W4210297789 hasConceptScore W4210297789C126894567 @default.
- W4210297789 hasConceptScore W4210297789C141071460 @default.
- W4210297789 hasConceptScore W4210297789C142724271 @default.
- W4210297789 hasConceptScore W4210297789C170033053 @default.
- W4210297789 hasConceptScore W4210297789C2776541429 @default.
- W4210297789 hasConceptScore W4210297789C2776886416 @default.
- W4210297789 hasConceptScore W4210297789C2779079599 @default.
- W4210297789 hasConceptScore W4210297789C2780091579 @default.
- W4210297789 hasConceptScore W4210297789C2780303639 @default.
- W4210297789 hasConceptScore W4210297789C2781451080 @default.
- W4210297789 hasConceptScore W4210297789C2909674915 @default.