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- W4210329087 abstract "Obesity is a chronic progressive condition. It is associated with adverse health outcomes affecting the cardiovascular, endocrine, gastrointestinal, urinary, respiratory, nervous, musculoskeletal, and reproductive systems. Obesity also increases the risk of certain malignancies and psychological comorbidities. The aetiopathogenesis of obesity-linked diseases is complex and not yet fully elucidated, however, clinical and experimental observations, as well as epidemiological studies, have identified a key role for adipocyte-derived factors, in particular from visceral adipose tissue and ectopic lipid deposition. These factors drive low-grade chronic systemic inflammation and mediate the development of at least some obesity-associated diseases. Increasing understanding of the mechanisms whereby obesity leads to a myriad of complications is urgently required to pave the way for development of novel evidence-based preventative and therapeutic strategies." @default.
- W4210329087 created "2022-02-08" @default.
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- W4210329087 date "2021-07-01" @default.
- W4210329087 modified "2023-09-27" @default.
- W4210329087 title "Medical Complications of Obesity" @default.
- W4210329087 doi "https://doi.org/10.1093/med/9780198870197.003.0224" @default.
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