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- W4210335089 abstract "FLOCK (flare clock) system is a novel platform that comprises of a nanoporous membrane based multilayer stack that works with passively secreted sweat. It is designed to capture eczema severity and circadian disruption caused due to its symptoms. This is aimed to be a wearable designed for efficient management of the flaring associated with Atopic Dermatitis (AD). The work presents the development of an eczematous flare tracker that detects Interleukin-31 and cortisol levels to create an AD management platform. The platform uses electrochemical detection for tracking these biomarkers in sweat. It is sensitive to IL-31 levels in various flare-based formulations tested through simulated sweating with a detection limit of 50 pg/mL and range 50–1000 pg/mL. On-body study highlights the ability of the wearable platform to track the rise and fall in the biomarkers’ levels. These levels are well correlated to salivary levels and commercial gold standard techniques (r > 0.8, R2 > 0.95)." @default.
- W4210335089 created "2022-02-08" @default.
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- W4210335089 date "2022-05-01" @default.
- W4210335089 modified "2023-10-14" @default.
- W4210335089 title "FLOCK -flare clock: Passive sweat-based eczematous flare detection system" @default.
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- W4210335089 doi "https://doi.org/10.1016/j.biosx.2022.100120" @default.
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