Matches in SemOpenAlex for { <https://semopenalex.org/work/W4210337545> ?p ?o ?g. }
- W4210337545 abstract "Abstract With the excessive genome plasticity, Acinetobacter baumannii has the capability to acquire and disseminate antimicrobial resistance genes that are often associated with mobile genetic elements (MGE). Analyzing the genetic environment of resistance genes often provides valuable information on the origin, emergence, evolution and spread of resistance. Thus, we characterized the genomic features of some clinical isolates of carbapenem-resistant A. baumannii to understand the role of diverse MGE and their genetic context that are responsible for the dissemination of carbapenem resistance genes. For this, a total of 17 clinical isolates of A. baumannii obtained from multiple hospitals in India between the years 2018 and 2019 were analysed. Antimicrobial resistance determinants, genetic context of resistance genes and molecular epidemiology were studied using whole genome sequencing. A high prevalence of bla OXA-23 was observed followed by the presence of dual carbapenemase, bla OXA-23 and bla NDM. Three novel Oxford sequence types were identified. Majority of the isolates belonged to dominant clone, IC2 followed by less prevalent clones such as IC7 and IC8. Complex diverse AbaR4 like and AbGRI-like islands belonging to IC2 lineage were identified. To the best of our knowledge, this is the first study that provides a comprehensive profiling of resistance islands along with the MGE, acquired antimicrobial resistance genes and the distribution of clonal lineages of carbapenem resistant A. baumannii from India." @default.
- W4210337545 created "2022-02-08" @default.
- W4210337545 creator A5002639768 @default.
- W4210337545 creator A5008638014 @default.
- W4210337545 creator A5009382154 @default.
- W4210337545 creator A5012353115 @default.
- W4210337545 creator A5013235525 @default.
- W4210337545 creator A5017282047 @default.
- W4210337545 creator A5035131839 @default.
- W4210337545 creator A5038077823 @default.
- W4210337545 creator A5045288208 @default.
- W4210337545 creator A5050926527 @default.
- W4210337545 creator A5074319161 @default.
- W4210337545 creator A5079476497 @default.
- W4210337545 date "2022-02-03" @default.
- W4210337545 modified "2023-10-17" @default.
- W4210337545 title "Genomic rearrangements of mobile genetic elements associated with carbapenem resistance of <i>Acinetobacter baumannii</i>" @default.
- W4210337545 cites W1901196343 @default.
- W4210337545 cites W1911845649 @default.
- W4210337545 cites W1920890130 @default.
- W4210337545 cites W1972145956 @default.
- W4210337545 cites W1982855075 @default.
- W4210337545 cites W2014477899 @default.
- W4210337545 cites W2031437556 @default.
- W4210337545 cites W2031611770 @default.
- W4210337545 cites W2051335715 @default.
- W4210337545 cites W2055783013 @default.
- W4210337545 cites W2088361440 @default.
- W4210337545 cites W2089011135 @default.
- W4210337545 cites W2111426588 @default.
- W4210337545 cites W2112364185 @default.
- W4210337545 cites W2115118328 @default.
- W4210337545 cites W2123916890 @default.
- W4210337545 cites W2165485591 @default.
- W4210337545 cites W2169649507 @default.
- W4210337545 cites W2170246082 @default.
- W4210337545 cites W2303950571 @default.
- W4210337545 cites W2462622937 @default.
- W4210337545 cites W2492695144 @default.
- W4210337545 cites W2508416401 @default.
- W4210337545 cites W2558746809 @default.
- W4210337545 cites W2789932157 @default.
- W4210337545 cites W2885680427 @default.
- W4210337545 cites W2896266492 @default.
- W4210337545 cites W2914431101 @default.
- W4210337545 cites W2937606013 @default.
- W4210337545 cites W2948049517 @default.
- W4210337545 cites W2952167528 @default.
- W4210337545 cites W2966058560 @default.
- W4210337545 cites W2980296480 @default.
- W4210337545 cites W2994575890 @default.
- W4210337545 cites W2995441271 @default.
- W4210337545 cites W2997782158 @default.
- W4210337545 cites W3013054750 @default.
- W4210337545 cites W3033135912 @default.
- W4210337545 cites W3156458251 @default.
- W4210337545 cites W3174528530 @default.
- W4210337545 doi "https://doi.org/10.1101/2022.02.03.478955" @default.
- W4210337545 hasPublicationYear "2022" @default.
- W4210337545 type Work @default.
- W4210337545 citedByCount "2" @default.
- W4210337545 countsByYear W42103375452023 @default.
- W4210337545 crossrefType "posted-content" @default.
- W4210337545 hasAuthorship W4210337545A5002639768 @default.
- W4210337545 hasAuthorship W4210337545A5008638014 @default.
- W4210337545 hasAuthorship W4210337545A5009382154 @default.
- W4210337545 hasAuthorship W4210337545A5012353115 @default.
- W4210337545 hasAuthorship W4210337545A5013235525 @default.
- W4210337545 hasAuthorship W4210337545A5017282047 @default.
- W4210337545 hasAuthorship W4210337545A5035131839 @default.
- W4210337545 hasAuthorship W4210337545A5038077823 @default.
- W4210337545 hasAuthorship W4210337545A5045288208 @default.
- W4210337545 hasAuthorship W4210337545A5050926527 @default.
- W4210337545 hasAuthorship W4210337545A5074319161 @default.
- W4210337545 hasAuthorship W4210337545A5079476497 @default.
- W4210337545 hasBestOaLocation W42103375451 @default.
- W4210337545 hasConcept C104317684 @default.
- W4210337545 hasConcept C114851261 @default.
- W4210337545 hasConcept C132533263 @default.
- W4210337545 hasConcept C133936738 @default.
- W4210337545 hasConcept C141231307 @default.
- W4210337545 hasConcept C151730666 @default.
- W4210337545 hasConcept C24432333 @default.
- W4210337545 hasConcept C2776315533 @default.
- W4210337545 hasConcept C2777637488 @default.
- W4210337545 hasConcept C2779343474 @default.
- W4210337545 hasConcept C501593827 @default.
- W4210337545 hasConcept C523546767 @default.
- W4210337545 hasConcept C54355233 @default.
- W4210337545 hasConcept C86803240 @default.
- W4210337545 hasConcept C94665300 @default.
- W4210337545 hasConceptScore W4210337545C104317684 @default.
- W4210337545 hasConceptScore W4210337545C114851261 @default.
- W4210337545 hasConceptScore W4210337545C132533263 @default.
- W4210337545 hasConceptScore W4210337545C133936738 @default.
- W4210337545 hasConceptScore W4210337545C141231307 @default.
- W4210337545 hasConceptScore W4210337545C151730666 @default.
- W4210337545 hasConceptScore W4210337545C24432333 @default.
- W4210337545 hasConceptScore W4210337545C2776315533 @default.
- W4210337545 hasConceptScore W4210337545C2777637488 @default.