Matches in SemOpenAlex for { <https://semopenalex.org/work/W4210346571> ?p ?o ?g. }
- W4210346571 abstract "Organ fibrogenesis is characterized by a common pathophysiological final pathway independent of the underlying progressive disease of the respective organ. This makes it particularly suitable as a therapeutic target. The Transregional Collaborative Research Center “Organ Fibrosis: From Mechanisms of Injury to Modulation of Disease” (referred to as SFB/TRR57) was hosted from 2009 to 2021 by the Medical Faculties of RWTH Aachen University and the University of Bonn. This consortium had the ultimate goal of discovering new common but also different fibrosis pathways in the liver and kidneys. It finally successfully identified new mechanisms and established novel therapeutic approaches to interfere with hepatic and renal fibrosis. This review covers the consortium's key kidney-related findings, where three overarching questions were addressed: (i) What are new relevant mechanisms and signaling pathways triggering renal fibrosis? (ii) What are new immunological mechanisms, cells and molecules that contribute to renal fibrosis?, and finally (iii) How can renal fibrosis be modulated?" @default.
- W4210346571 created "2022-02-08" @default.
- W4210346571 creator A5001027249 @default.
- W4210346571 creator A5009349672 @default.
- W4210346571 creator A5028674815 @default.
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- W4210346571 creator A5049305761 @default.
- W4210346571 creator A5052802894 @default.
- W4210346571 creator A5055719124 @default.
- W4210346571 creator A5065533886 @default.
- W4210346571 creator A5069103831 @default.
- W4210346571 creator A5071291097 @default.
- W4210346571 creator A5079522186 @default.
- W4210346571 date "2022-01-12" @default.
- W4210346571 modified "2023-09-25" @default.
- W4210346571 title "New Aspects of Kidney Fibrosis–From Mechanisms of Injury to Modulation of Disease" @default.
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