FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4210353583> ?p ?o ?g. }

• W4210353583 abstract "To determine whether serum neurofilament light chain (sNfL) levels are suppressed in patients with the clinically isolated syndrome (CIS) following narrowband ultraviolet B phototherapy (UVB-PT).sNfL levels were measured using a sensitive single-molecule array assay at baseline and up to 12 months in 17 patients with CIS, 10 of whom received UVB-PT, and were compared with healthy control (HC) and early relapsing remitting multiple sclerosis (RRMS) group. sNfL levels were correlated with magnetic resonance imaging total lesion volume (LV) determined using icobrain version 4.4.1 and with clinical outcomes.Baseline median sNfL levels were significantly higher in the CIS (20.6 pg/mL, interquartile range [IQR] 13.7-161.4) and RRMS groups (36.6 pg/ml [IQR] 16.2-212.2) than in HC (10.7 pg/ml [IQR] 4.9-21.5) (p = .012 and p = .0002, respectively), and were strongly correlated with T2 and T1 LV at 12 months (r = .800; p = .014 and r = .833; p = .008, respectively) in the CIS group. Analysis of changes in sNfL levels over time in the CIS group showed a significant cumulative suppressive effect of UVB-PT in the first 3 months (UVB-PT -10.6% vs non-UVB-PT +58.3%; p = .04) following which the levels in the two groups converged and continued to fall.Our findings provide the basis for further studies to determine the utility of sNfL levels as a marker of neuro-axonal damage in CIS and early MS and for assessing the efficacy of new therapeutic interventions such as UVB-PT." @default.
• W4210353583 created "2022-02-08" @default.
• W4210353583 creator A5005966031 @default.
• W4210353583 creator A5008704373 @default.
• W4210353583 creator A5009007116 @default.
• W4210353583 creator A5011937215 @default.
• W4210353583 creator A5013321215 @default.
• W4210353583 creator A5022332929 @default.
• W4210353583 creator A5022756755 @default.
• W4210353583 creator A5045590592 @default.
• W4210353583 creator A5058252357 @default.
• W4210353583 creator A5084095818 @default.
• W4210353583 creator A5089070827 @default.
• W4210353583 date "2022-01-27" @default.
• W4210353583 modified "2023-10-14" @default.
• W4210353583 title "Changes in serum neurofilament light chain levels following narrowband ultraviolet B phototherapy in clinically isolated syndrome" @default.
• W4210353583 cites W2057119898 @default.
• W4210353583 cites W2118698089 @default.
• W4210353583 cites W2122545833 @default.
• W4210353583 cites W2142577589 @default.
• W4210353583 cites W2151840920 @default.
• W4210353583 cites W2583069747 @default.
• W4210353583 cites W2614808368 @default.
• W4210353583 cites W2677724969 @default.
• W4210353583 cites W2801930009 @default.
• W4210353583 cites W2810232847 @default.
• W4210353583 cites W2889223700 @default.
• W4210353583 cites W2910539598 @default.
• W4210353583 cites W2914396477 @default.
• W4210353583 cites W2947496337 @default.
• W4210353583 cites W2981498809 @default.
• W4210353583 cites W3028430208 @default.
• W4210353583 cites W3133842241 @default.
• W4210353583 cites W4210353583 @default.
• W4210353583 doi "https://doi.org/10.1002/brb3.2494" @default.
• W4210353583 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35084124" @default.
• W4210353583 hasPublicationYear "2022" @default.
• W4210353583 type Work @default.
• W4210353583 citedByCount "3" @default.
• W4210353583 countsByYear W42103535832022 @default.
• W4210353583 countsByYear W42103535832023 @default.
• W4210353583 crossrefType "journal-article" @default.
• W4210353583 hasAuthorship W4210353583A5005966031 @default.
• W4210353583 hasAuthorship W4210353583A5008704373 @default.
• W4210353583 hasAuthorship W4210353583A5009007116 @default.
• W4210353583 hasAuthorship W4210353583A5011937215 @default.
• W4210353583 hasAuthorship W4210353583A5013321215 @default.
• W4210353583 hasAuthorship W4210353583A5022332929 @default.
• W4210353583 hasAuthorship W4210353583A5022756755 @default.
• W4210353583 hasAuthorship W4210353583A5045590592 @default.
• W4210353583 hasAuthorship W4210353583A5058252357 @default.
• W4210353583 hasAuthorship W4210353583A5084095818 @default.
• W4210353583 hasAuthorship W4210353583A5089070827 @default.
• W4210353583 hasBestOaLocation W42103535831 @default.
• W4210353583 hasConcept C119060515 @default.
• W4210353583 hasConcept C126322002 @default.
• W4210353583 hasConcept C126838900 @default.
• W4210353583 hasConcept C142724271 @default.
• W4210353583 hasConcept C143409427 @default.
• W4210353583 hasConcept C203014093 @default.
• W4210353583 hasConcept C2780640218 @default.
• W4210353583 hasConcept C2781028063 @default.
• W4210353583 hasConcept C2781156865 @default.
• W4210353583 hasConcept C2989005 @default.
• W4210353583 hasConcept C71924100 @default.
• W4210353583 hasConcept C90924648 @default.
• W4210353583 hasConceptScore W4210353583C119060515 @default.
• W4210353583 hasConceptScore W4210353583C126322002 @default.
• W4210353583 hasConceptScore W4210353583C126838900 @default.
• W4210353583 hasConceptScore W4210353583C142724271 @default.
• W4210353583 hasConceptScore W4210353583C143409427 @default.
• W4210353583 hasConceptScore W4210353583C203014093 @default.
• W4210353583 hasConceptScore W4210353583C2780640218 @default.
• W4210353583 hasConceptScore W4210353583C2781028063 @default.
• W4210353583 hasConceptScore W4210353583C2781156865 @default.
• W4210353583 hasConceptScore W4210353583C2989005 @default.
• W4210353583 hasConceptScore W4210353583C71924100 @default.
• W4210353583 hasConceptScore W4210353583C90924648 @default.
• W4210353583 hasFunder F4320320368 @default.
• W4210353583 hasIssue "2" @default.
• W4210353583 hasLocation W42103535831 @default.
• W4210353583 hasLocation W42103535832 @default.
• W4210353583 hasLocation W42103535833 @default.
• W4210353583 hasLocation W42103535834 @default.
• W4210353583 hasLocation W42103535835 @default.
• W4210353583 hasOpenAccess W4210353583 @default.
• W4210353583 hasPrimaryLocation W42103535831 @default.
• W4210353583 hasRelatedWork W1975806676 @default.
• W4210353583 hasRelatedWork W1992383729 @default.
• W4210353583 hasRelatedWork W2016741243 @default.
• W4210353583 hasRelatedWork W2020834477 @default.
• W4210353583 hasRelatedWork W2045784956 @default.
• W4210353583 hasRelatedWork W2062532180 @default.
• W4210353583 hasRelatedWork W2102473502 @default.
• W4210353583 hasRelatedWork W2395410554 @default.
• W4210353583 hasRelatedWork W2463720534 @default.
• W4210353583 hasRelatedWork W2775593129 @default.
• W4210353583 hasVolume "12" @default.
• W4210353583 isParatext "false" @default.
• W4210353583 isRetracted "false" @default.

• next