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• W4210361060 endingPage "1835" @default.
• W4210361060 startingPage "1835" @default.
• W4210361060 abstract "Much attention has been recently drawn to studying melatonin - a hormone whose synthesis was first found in the epiphysis (pineal gland). This interest can be due to discovering the role of melatonin in numerous physiological processes. It was the discovery of melatonin synthesis in endocrine organs (pineal gland), neural structures (Purkinje cells in the cerebellum, retinal photoreceptors), and immunocompetent cells (T lymphocytes, NK cells, mast cells) that triggered the evolution of new approaches to the unifield signal regulation of homeostasis, which, at the turn of the 21st century, lead to the creation of a new integral biomedical discipline - neuroimmunoendocrinology. While numerous hormones have been verified over the last decade outside the classical locations of their formation, melatonin occupies an exclusive position with regard to the diversity of locations where it is synthesized and secreted. This review provides an overview and discussion of the major data regarding the role of melatonin in various physiological and pathological processes, which affords grounds for considering melatonin as the cornerstone on which neuroimmunoendocrinology has been built as an integral concept of homeostasis regulation." @default.
• W4210361060 created "2022-02-08" @default.
• W4210361060 creator A5003057712 @default.
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• W4210361060 creator A5069613082 @default.
• W4210361060 date "2022-02-06" @default.
• W4210361060 modified "2023-10-05" @default.
• W4210361060 title "Melatonin as the Cornerstone of Neuroimmunoendocrinology" @default.
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