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• W4210366653 abstract "Complex diagnostic profiles (i.e., clusters of comorbid disorders) may be present in adolescence with long-lasting effects later in life. Little is known about their developmental transitions to adulthood as well as potential risk factors. This study aimed to identify the diagnostic profiles in adolescence and emerging adulthood, patterns of transitions and risk factors. A sample of 1062 Mexican adolescents (43.22% men, M = 14.19 years at baseline, SD = 1.68) was assessed for psychiatric disorders at adolescence and emerging adulthood. Latent class analysis was used to identify diagnostic profiles. Profile transition was studied using multi-state modeling between the life periods. Logistic regression was utilized to study risk factor influence on profile development in adulthood. Three diagnostic profiles (i.e., minimal disorder/no-psychopathology; and two clinical profiles: internalizing and externalizing) were identified in both periods. Anxiety disorders were the most frequent psychiatric presentation in adolescence, while depression was the most prevalent disorder in adulthood. More than 15% of participants showed a clinical profile regardless life period. Comorbidity was present in 57% of participants with a clinical psychiatric profile. Finally, common (suicidal behavior) and specific risk factors (sex, parents’ education and income) predicted transitions to profiles from adolescence to emerging adulthood. Psychiatric disorders are frequently observed adopting a complex diagnostic profile in both adolescence and emerging adulthood. Comorbidity seems to be common in both life periods. Developmental issues and comorbidity should be considered for health service provision and treatment choice. El malestar psiquiátrico puede incluir presentaciones diagnósticas complejas (perfiles diagnósticos) en la adolescencia. Dichas presentaciones tienen influencia duradera en la adultez. Si bien poco se sabe de cómo evolucionan estos perfiles hacia la adultez. Este estudio pretendía identificar los perfiles diagnósticos en la adolescencia y la juventud, sus patrones de transición y factores de riesgo. Mil sesenta y dos adolescentes mexicanos (43,22% chicos, M = 14,19 años en línea base, DT = 1,68) fueron evaluados respecto a trastornos psiquiátricos en la adolescencia y la juventud. Se identificaron perfiles diagnósticos mediante modelos de clase latente. Se usaron modelos multiestado para estudiar transiciones entre periodos vitales y regresión logística para analizar la influencia de factores de riesgo en las transiciones entre perfiles. Se identificaron 3 perfiles diagnósticos (i.e. no-psicopatología y 2 clínicos: internalizante y externalizante) para ambos periodos vitales. Los trastornos más prevalentes fueron internalizantes en ambos periodos. Más del 15% de participantes mostró un perfil diagnóstico clínico. La comorbilidad psiquiátrica se dio en el 57% de los casos con perfil clínico. Finalmente, la transición a perfiles clínicos en la juventud se explicó mediante factores de riesgo comunes (conducta suicida) y específicos del perfil (sexo, educación parental y nivel de ingresos). El malestar psiquiátrico puede presentar formas complejas, tanto en la adolescencia como en la juventud. La comorbilidad suele ser algo común en ambos periodos vitales. Por ello, estos aspectos deben ser considerados a la hora de indicar el tratamiento y planificar la atención clínica." @default.
• W4210366653 created "2022-02-08" @default.
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• W4210366653 date "2023-01-01" @default.
• W4210366653 modified "2023-10-16" @default.
• W4210366653 title "Diagnostic profiles in adolescence and emerging adulthood: Transition patterns and risk factors" @default.
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• W4210366653 doi "https://doi.org/10.1016/j.rpsm.2022.01.002" @default.
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