Matches in SemOpenAlex for { <https://semopenalex.org/work/W4210408032> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W4210408032 endingPage "100144" @default.
- W4210408032 startingPage "100144" @default.
- W4210408032 abstract "Acinar cell carcinoma of the pancreas (ACC) is a rare malignancy, accounting for approximately 1-2% of all pancreatic cancers. Up to a quarter of ACCs are estimated to contain a significant component of another histology such as neuroendocrine or ductal adenocarcinoma. Prognosis and management remain uncertain for these mixed tumors. A 71-year-old was initially diagnosed with biopsy-proven metastatic pancreatic ACC and treated with FOLFOX. Subsequent biopsy of a progressing metastatic site revealed ductal adenocarcinoma, and liquid biopsy showed a PRKAR1A-RAF1 fusion. The patient had a partial response to FOLFOX and died nine months after initial diagnosis. This case highlights a metastatic presentation of mixed pancreatic acinar cell-ductal adenocarcinoma, its reasonable response to treatment with FOLFOX, and overall survival which was driven by the more aggressive ductal component. We also report the presence of a RAF1 rearrangement, which may present a possible therapeutic target in these rare tumors." @default.
- W4210408032 created "2022-02-08" @default.
- W4210408032 creator A5001762214 @default.
- W4210408032 creator A5012785119 @default.
- W4210408032 creator A5014500064 @default.
- W4210408032 creator A5024742125 @default.
- W4210408032 creator A5051208518 @default.
- W4210408032 date "2022-02-01" @default.
- W4210408032 modified "2023-09-23" @default.
- W4210408032 title "Mixed Pancreatic Acinar Cell-Ductal Adenocarcinoma: Complexities in Diagnosis and Treatment" @default.
- W4210408032 cites W150339747 @default.
- W4210408032 cites W1836362594 @default.
- W4210408032 cites W1948956592 @default.
- W4210408032 cites W2038294488 @default.
- W4210408032 cites W2053797742 @default.
- W4210408032 cites W2084663569 @default.
- W4210408032 cites W2087122416 @default.
- W4210408032 cites W2087404248 @default.
- W4210408032 cites W2091119990 @default.
- W4210408032 cites W2091611741 @default.
- W4210408032 cites W2110920215 @default.
- W4210408032 cites W2501023632 @default.
- W4210408032 cites W2554949911 @default.
- W4210408032 cites W2566746104 @default.
- W4210408032 cites W2580957273 @default.
- W4210408032 cites W2913791807 @default.
- W4210408032 cites W3023400487 @default.
- W4210408032 cites W3083364184 @default.
- W4210408032 cites W4375905885 @default.
- W4210408032 doi "https://doi.org/10.1016/j.cpccr.2022.100144" @default.
- W4210408032 hasPublicationYear "2022" @default.
- W4210408032 type Work @default.
- W4210408032 citedByCount "0" @default.
- W4210408032 crossrefType "journal-article" @default.
- W4210408032 hasAuthorship W4210408032A5001762214 @default.
- W4210408032 hasAuthorship W4210408032A5012785119 @default.
- W4210408032 hasAuthorship W4210408032A5014500064 @default.
- W4210408032 hasAuthorship W4210408032A5024742125 @default.
- W4210408032 hasAuthorship W4210408032A5051208518 @default.
- W4210408032 hasBestOaLocation W42104080321 @default.
- W4210408032 hasConcept C121608353 @default.
- W4210408032 hasConcept C126322002 @default.
- W4210408032 hasConcept C142724271 @default.
- W4210408032 hasConcept C143998085 @default.
- W4210408032 hasConcept C2775934546 @default.
- W4210408032 hasConcept C2776694085 @default.
- W4210408032 hasConcept C2778260052 @default.
- W4210408032 hasConcept C2778764654 @default.
- W4210408032 hasConcept C2779399171 @default.
- W4210408032 hasConcept C2780258809 @default.
- W4210408032 hasConcept C2780862961 @default.
- W4210408032 hasConcept C2780962732 @default.
- W4210408032 hasConcept C2781182431 @default.
- W4210408032 hasConcept C526805850 @default.
- W4210408032 hasConcept C530470458 @default.
- W4210408032 hasConcept C71924100 @default.
- W4210408032 hasConcept C90924648 @default.
- W4210408032 hasConceptScore W4210408032C121608353 @default.
- W4210408032 hasConceptScore W4210408032C126322002 @default.
- W4210408032 hasConceptScore W4210408032C142724271 @default.
- W4210408032 hasConceptScore W4210408032C143998085 @default.
- W4210408032 hasConceptScore W4210408032C2775934546 @default.
- W4210408032 hasConceptScore W4210408032C2776694085 @default.
- W4210408032 hasConceptScore W4210408032C2778260052 @default.
- W4210408032 hasConceptScore W4210408032C2778764654 @default.
- W4210408032 hasConceptScore W4210408032C2779399171 @default.
- W4210408032 hasConceptScore W4210408032C2780258809 @default.
- W4210408032 hasConceptScore W4210408032C2780862961 @default.
- W4210408032 hasConceptScore W4210408032C2780962732 @default.
- W4210408032 hasConceptScore W4210408032C2781182431 @default.
- W4210408032 hasConceptScore W4210408032C526805850 @default.
- W4210408032 hasConceptScore W4210408032C530470458 @default.
- W4210408032 hasConceptScore W4210408032C71924100 @default.
- W4210408032 hasConceptScore W4210408032C90924648 @default.
- W4210408032 hasLocation W42104080321 @default.
- W4210408032 hasLocation W42104080322 @default.
- W4210408032 hasOpenAccess W4210408032 @default.
- W4210408032 hasPrimaryLocation W42104080321 @default.
- W4210408032 hasRelatedWork W12061583 @default.
- W4210408032 hasRelatedWork W12145801 @default.
- W4210408032 hasRelatedWork W17733091 @default.
- W4210408032 hasRelatedWork W17992501 @default.
- W4210408032 hasRelatedWork W20825895 @default.
- W4210408032 hasRelatedWork W2244483 @default.
- W4210408032 hasRelatedWork W3121219 @default.
- W4210408032 hasRelatedWork W8036556 @default.
- W4210408032 hasRelatedWork W8428010 @default.
- W4210408032 hasRelatedWork W9051876 @default.
- W4210408032 isParatext "false" @default.
- W4210408032 isRetracted "false" @default.
- W4210408032 workType "article" @default.