Matches in SemOpenAlex for { <https://semopenalex.org/work/W4210410054> ?p ?o ?g. }
- W4210410054 endingPage "11" @default.
- W4210410054 startingPage "1" @default.
- W4210410054 abstract "Gastric adenocarcinoma (GAC) continues to be a prevalent global concern. Differences in incidence are predominantly due to geographic locations with Asia contributing to majority of cases. Another parallel challenge is due to heterogenous molecular and immune profiles of GAC along with varying clinicopathological features of patients. In most countries, GACs are diagnosed late in an advanced stage as the early detection infrastructure cannot be implemented or not feasible. Future advances in liquid biopsies could change all that.The authors focus on the recent advances in the management of advanced GAC patients w but also address localized GAC. Herein, the authors review the most contemporary treatments and promising breakthroughs.The addition of immunotherapy to standard of care has changed the outlook of advanced GAC patients. The authors anticipate continued advances in the development of immunotherapy both in surgically resectable and unresectable GACs. Targeting the ERBB2 (HER2) protein pathway remains uniquely important in GACs with ERBB2 (HER2) protein positivity. Currently, many novel anti-ERBB2 (HER2) protein therapies are under investigation. The next generation of GAC patients will derive considerably more benefit as the therapeutic landscape becomes more complex coupled with challenges in biomarker platforms and new drug development." @default.
- W4210410054 created "2022-02-08" @default.
- W4210410054 creator A5013187820 @default.
- W4210410054 creator A5025614289 @default.
- W4210410054 creator A5028350326 @default.
- W4210410054 creator A5044064524 @default.
- W4210410054 date "2022-01-31" @default.
- W4210410054 modified "2023-09-26" @default.
- W4210410054 title "Pharmaceutical advances in the treatment of gastric adenocarcinoma" @default.
- W4210410054 cites W2008322008 @default.
- W4210410054 cites W2100439220 @default.
- W4210410054 cites W2104759721 @default.
- W4210410054 cites W2111237964 @default.
- W4210410054 cites W2115072149 @default.
- W4210410054 cites W2119349657 @default.
- W4210410054 cites W2126547130 @default.
- W4210410054 cites W2144182296 @default.
- W4210410054 cites W2149895338 @default.
- W4210410054 cites W2165982376 @default.
- W4210410054 cites W2185378752 @default.
- W4210410054 cites W2598685895 @default.
- W4210410054 cites W2603648359 @default.
- W4210410054 cites W2739132742 @default.
- W4210410054 cites W2769419513 @default.
- W4210410054 cites W2784868445 @default.
- W4210410054 cites W2797145364 @default.
- W4210410054 cites W2888288613 @default.
- W4210410054 cites W2891146116 @default.
- W4210410054 cites W2892163061 @default.
- W4210410054 cites W2897154408 @default.
- W4210410054 cites W2938774982 @default.
- W4210410054 cites W2947097055 @default.
- W4210410054 cites W3004602122 @default.
- W4210410054 cites W3009140068 @default.
- W4210410054 cites W3022265620 @default.
- W4210410054 cites W3084398045 @default.
- W4210410054 cites W3089400954 @default.
- W4210410054 cites W3125059231 @default.
- W4210410054 cites W3128646645 @default.
- W4210410054 cites W3134008684 @default.
- W4210410054 cites W3145734939 @default.
- W4210410054 cites W3147820834 @default.
- W4210410054 cites W3171305553 @default.
- W4210410054 cites W3171517418 @default.
- W4210410054 cites W3184006782 @default.
- W4210410054 cites W3185533315 @default.
- W4210410054 cites W3195617271 @default.
- W4210410054 doi "https://doi.org/10.1080/14656566.2022.2032644" @default.
- W4210410054 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35098851" @default.
- W4210410054 hasPublicationYear "2022" @default.
- W4210410054 type Work @default.
- W4210410054 citedByCount "0" @default.
- W4210410054 crossrefType "journal-article" @default.
- W4210410054 hasAuthorship W4210410054A5013187820 @default.
- W4210410054 hasAuthorship W4210410054A5025614289 @default.
- W4210410054 hasAuthorship W4210410054A5028350326 @default.
- W4210410054 hasAuthorship W4210410054A5044064524 @default.
- W4210410054 hasConcept C121608353 @default.
- W4210410054 hasConcept C126322002 @default.
- W4210410054 hasConcept C177713679 @default.
- W4210410054 hasConcept C185592680 @default.
- W4210410054 hasConcept C2777701055 @default.
- W4210410054 hasConcept C2780035454 @default.
- W4210410054 hasConcept C2781182431 @default.
- W4210410054 hasConcept C2781197716 @default.
- W4210410054 hasConcept C2993283237 @default.
- W4210410054 hasConcept C55493867 @default.
- W4210410054 hasConcept C64903051 @default.
- W4210410054 hasConcept C71924100 @default.
- W4210410054 hasConcept C98274493 @default.
- W4210410054 hasConceptScore W4210410054C121608353 @default.
- W4210410054 hasConceptScore W4210410054C126322002 @default.
- W4210410054 hasConceptScore W4210410054C177713679 @default.
- W4210410054 hasConceptScore W4210410054C185592680 @default.
- W4210410054 hasConceptScore W4210410054C2777701055 @default.
- W4210410054 hasConceptScore W4210410054C2780035454 @default.
- W4210410054 hasConceptScore W4210410054C2781182431 @default.
- W4210410054 hasConceptScore W4210410054C2781197716 @default.
- W4210410054 hasConceptScore W4210410054C2993283237 @default.
- W4210410054 hasConceptScore W4210410054C55493867 @default.
- W4210410054 hasConceptScore W4210410054C64903051 @default.
- W4210410054 hasConceptScore W4210410054C71924100 @default.
- W4210410054 hasConceptScore W4210410054C98274493 @default.
- W4210410054 hasFunder F4320312961 @default.
- W4210410054 hasLocation W42104100541 @default.
- W4210410054 hasLocation W42104100542 @default.
- W4210410054 hasOpenAccess W4210410054 @default.
- W4210410054 hasPrimaryLocation W42104100541 @default.
- W4210410054 hasRelatedWork W1970760176 @default.
- W4210410054 hasRelatedWork W2356594988 @default.
- W4210410054 hasRelatedWork W2372490492 @default.
- W4210410054 hasRelatedWork W2390888655 @default.
- W4210410054 hasRelatedWork W2392430486 @default.
- W4210410054 hasRelatedWork W2899882025 @default.
- W4210410054 hasRelatedWork W2902633836 @default.
- W4210410054 hasRelatedWork W4205540160 @default.
- W4210410054 hasRelatedWork W4318026870 @default.
- W4210410054 hasRelatedWork W2132266714 @default.