FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4210431674> ?p ?o ?g. }

• W4210431674 endingPage "18" @default.
• W4210431674 startingPage "5" @default.
• W4210431674 abstract "Diarrhea is the most common adverse reaction of anticancer drugs, as well as radiation therapy of the pelvic organs or abdominal cavity: the incidence of diarrhea of different seveity reaches 80% during chemotherapy and / or radiation therapy; one third of these patients develop severe diarrhea (3rd or 4th degree). Most often, drug-induced diarrhea occurs during chemotherapy, using 5-fluorouracil or irinotecan, taking new anticancer drugs from the classes of checkpoint inhibitors, monoclonal antibodies, tyrosine kinase inhibitors. The most common mechanisms underlying the development of drug-induced diarrhea are damage to the intestinal mucosa, impaired absorption of proteins, carbohydrates, fats, inflammation, a perverse immune response, microflora imbalance, and others.&#x0D; Algorithms for the management of patients with severe diarrhea include suspension (grade 1-2, 3) or complete cessation (grade 4, grade 3) of the use of an antineoplastic agent an inducer, prescribing drugs that reduce intestinal motility (loperamide) while excluding the infectious nature of diarrhea, intravenous methylprednisolone (for example, diarrhea caused by monoclinal antibodies in the absence of suspicion of potential bowel perforation). In cases where drug-induced diarrhea lasts more than 48 hours, or a patient reports symptoms of dehydration, or a fever occurs, urgent hospitalization is necessary.&#x0D; The objective of this review is to analyze scientific literature data on the prevalence, pathophysiological mechanisms and risk factors for the development of diarrhea associated with the intake of anticancer drugs, as well as its prevention and treatment." @default.
• W4210431674 created "2022-02-08" @default.
• W4210431674 creator A5013868193 @default.
• W4210431674 creator A5063633398 @default.
• W4210431674 creator A5088451600 @default.
• W4210431674 creator A5091837013 @default.
• W4210431674 date "2021-10-15" @default.
• W4210431674 modified "2023-10-16" @default.
• W4210431674 title "Drug-induced diarrhea associated with antineoplastic drugs" @default.
• W4210431674 cites W1543949018 @default.
• W4210431674 cites W1893993642 @default.
• W4210431674 cites W1919810009 @default.
• W4210431674 cites W1969116196 @default.
• W4210431674 cites W1982684841 @default.
• W4210431674 cites W1987273031 @default.
• W4210431674 cites W1994016697 @default.
• W4210431674 cites W2002475451 @default.
• W4210431674 cites W2022575295 @default.
• W4210431674 cites W2028242534 @default.
• W4210431674 cites W2029901101 @default.
• W4210431674 cites W2033110631 @default.
• W4210431674 cites W2041436152 @default.
• W4210431674 cites W2043709013 @default.
• W4210431674 cites W2053508459 @default.
• W4210431674 cites W2054582441 @default.
• W4210431674 cites W2055993707 @default.
• W4210431674 cites W2057145505 @default.
• W4210431674 cites W2057977761 @default.
• W4210431674 cites W2058618722 @default.
• W4210431674 cites W2063062781 @default.
• W4210431674 cites W2071359087 @default.
• W4210431674 cites W2081299257 @default.
• W4210431674 cites W2085921016 @default.
• W4210431674 cites W2088689565 @default.
• W4210431674 cites W2092123158 @default.
• W4210431674 cites W2097257602 @default.
• W4210431674 cites W2099556905 @default.
• W4210431674 cites W2110835998 @default.
• W4210431674 cites W2111662961 @default.
• W4210431674 cites W2113176208 @default.
• W4210431674 cites W2123526148 @default.
• W4210431674 cites W2125060052 @default.
• W4210431674 cites W2125760261 @default.
• W4210431674 cites W2127101185 @default.
• W4210431674 cites W2131063689 @default.
• W4210431674 cites W2138037152 @default.
• W4210431674 cites W2142161000 @default.
• W4210431674 cites W2149746825 @default.
• W4210431674 cites W2155098052 @default.
• W4210431674 cites W2161097769 @default.
• W4210431674 cites W2163953363 @default.
• W4210431674 cites W2168776493 @default.
• W4210431674 cites W2171139285 @default.
• W4210431674 cites W2289407340 @default.
• W4210431674 cites W2314922821 @default.
• W4210431674 cites W2334075009 @default.
• W4210431674 cites W2396149304 @default.
• W4210431674 cites W2527922674 @default.
• W4210431674 cites W2528491191 @default.
• W4210431674 cites W2546623302 @default.
• W4210431674 cites W2558428915 @default.
• W4210431674 cites W2736166064 @default.
• W4210431674 cites W2747505649 @default.
• W4210431674 cites W2772263265 @default.
• W4210431674 cites W2785957197 @default.
• W4210431674 cites W2794872274 @default.
• W4210431674 cites W2809600902 @default.
• W4210431674 cites W2864040241 @default.
• W4210431674 cites W2888923564 @default.
• W4210431674 cites W2908686623 @default.
• W4210431674 cites W2991386831 @default.
• W4210431674 cites W3032110249 @default.
• W4210431674 cites W3044357519 @default.
• W4210431674 cites W3113078327 @default.
• W4210431674 cites W4211193262 @default.
• W4210431674 cites W4211216862 @default.
• W4210431674 doi "https://doi.org/10.17816/mechnikov84052" @default.
• W4210431674 hasPublicationYear "2021" @default.
• W4210431674 type Work @default.
• W4210431674 citedByCount "0" @default.
• W4210431674 crossrefType "journal-article" @default.
• W4210431674 hasAuthorship W4210431674A5013868193 @default.
• W4210431674 hasAuthorship W4210431674A5063633398 @default.
• W4210431674 hasAuthorship W4210431674A5088451600 @default.
• W4210431674 hasAuthorship W4210431674A5091837013 @default.
• W4210431674 hasConcept C121608353 @default.
• W4210431674 hasConcept C126322002 @default.
• W4210431674 hasConcept C197934379 @default.
• W4210431674 hasConcept C203014093 @default.
• W4210431674 hasConcept C2776694085 @default.
• W4210431674 hasConcept C2777573665 @default.
• W4210431674 hasConcept C2779802037 @default.
• W4210431674 hasConcept C2780035454 @default.
• W4210431674 hasConcept C2780259306 @default.
• W4210431674 hasConcept C526805850 @default.
• W4210431674 hasConcept C71924100 @default.
• W4210431674 hasConcept C90924648 @default.
• W4210431674 hasConcept C98274493 @default.

• next