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- W4210513180 abstract "Abstract Background: The purpose of this study was to detect whether antibiotic therapy during IVF-ET cycle is as effective as aspiration of hydrosalpinx fluid under ultrasound guidance in preventing the adverse effect of hydrosalpinx on IVF-ET results. Methods: During the period between November 2012 and January 2020, patients with ultrasound visible hydrosalpinges undergoing IVF-ET who refused to undergo laparoscopic salpingectomy or not eligible for laparoscopy were advised to receive antibiotic therapy during IVF-ET cycle or to undergo aspiration of hydrosalpinx fluid under ultrasound guidance at the time of ovum pick up. A retrospective analysis was done for the results of IVF-ET cycles of patients who received antibiotic therapy ( n = 52 ) or underwent aspiration of hydrosalpinx fluid under ultrasound guidance ( n = 76). In the aspiration group, the tip of the suction needle was introduced into the hydrosalpinx to aspirate the hydrosalpinx fluid after completing the ovum pick up. In the antibiotic group, doxycycline (100 mg/12 h) was commenced one week before ovum pick up and was continued for another week after ovum pick up. Results: The implantation, clinical pregnancy, ongoing pregnancy and live birth rates were significantly higher in the aspiration group ( 16.67%% Vs. 8.33%, P value =0.029, 32.89% Vs. 15.38% P value = 0.026, 30.26% Vs. 13.46%,P value =0.028 and 28,95% Vs. 13.46% P value = 0.04 respectively). Conclusion: The aspiration of hydrosalpinx fluid under ultrasound guidance is more effective than antibiotic therapy in preventing the negative impact of hydrosalpinx on the results of IVF-ET. The results of the current study should be proved by subsequent randomized controlled studies." @default.
- W4210513180 created "2022-02-08" @default.
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- W4210513180 date "2021-01-05" @default.
- W4210513180 modified "2023-09-26" @default.
- W4210513180 title "Extended Doxycycline Treatment Versus Aspiration of Hydrosalpingeal Fluid in the Management of Patients With Ultrasound Visible Hydrosalpinx Who Refused or Not Eligible to Undergo Salpingectomy Prior to IVF-ET" @default.
- W4210513180 doi "https://doi.org/10.21203/rs.3.rs-138894/v1" @default.
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