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- W4210555860 abstract "Implant-associated infections (IAI) remains a common and devastating complication in orthopedic surgery. To reduce the incidence of IAI, implants with intrinsic antibacterial activity have been proposed. The surface functionalization and structure optimization of metallic implants can be achieved by surface modification using the phosphate chemical conversion (PCC) technique. Zinc (Zn) has strong antibacterial behavior toward a broad-spectrum of bacteria. Herein, Zn was incorporated into strontium-calcium-phosphate (SrCaP) coatings on titanium (Ti) via PCC method, and the influence of its doping amount on the phase, microstructure, antibacterial activity, and biocompatibility of the composite coating was researched. The results indicated that traces of Zn doping produced grain refinement of SrCaP coating with no significant effect on its phase and surface properties, while a higher Zn content induced its phase and microstructure transformed into zinc-strontium-phosphate (SrZn2(PO4)2). SrCaP-Zn1 and SrCaP-Zn4 represented trace and high content Zn-doped coatings, respectively, which exhibited a similar bacterial attachment for a short time but showed inhibition of biofilm formation after continuous incubation up to 24 h. The killing rates of SrCaP-Zn1 coating for Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) reached 61.25% and 55.38%, respectively. While that data increased to 83.01% and 71.28% on SrCaP-Zn4 coating due to the more-releasing Zn2+. Furthermore, in vitro culture of MC3T3-E1 cells proved that the Zn-doped coatings also possessed excellent biocompatibility. This study provides a new perception for the phase and microstructural optimization of phosphate coatings on implant surfaces, as well as fabricating promising coatings with excellent biocompatibility and antimicrobial properties against IAI." @default.
- W4210555860 created "2022-02-08" @default.
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- W4210555860 date "2022-02-03" @default.
- W4210555860 modified "2023-10-18" @default.
- W4210555860 title "Zinc-Doping Induces Evolution of Biocompatible Strontium–Calcium-Phosphate Conversion Coating on Titanium to Improve Antibacterial Property" @default.
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- W4210555860 cites W1986907816 @default.
- W4210555860 cites W1998839841 @default.
- W4210555860 cites W2019459694 @default.
- W4210555860 cites W2027329930 @default.
- W4210555860 cites W2033406469 @default.
- W4210555860 cites W2055447917 @default.
- W4210555860 cites W2062735382 @default.
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- W4210555860 cites W2136959280 @default.
- W4210555860 cites W2150743378 @default.
- W4210555860 cites W2193505608 @default.
- W4210555860 cites W2211732979 @default.
- W4210555860 cites W2317685136 @default.
- W4210555860 cites W2319753713 @default.
- W4210555860 cites W2332853586 @default.
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- W4210555860 cites W2594245834 @default.
- W4210555860 cites W2736910592 @default.
- W4210555860 cites W2742683137 @default.
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- W4210555860 cites W2804715533 @default.
- W4210555860 cites W2806936241 @default.
- W4210555860 cites W2905498328 @default.
- W4210555860 cites W2907943221 @default.
- W4210555860 cites W2909776368 @default.
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- W4210555860 cites W2965507639 @default.
- W4210555860 cites W2966188773 @default.
- W4210555860 cites W2982881583 @default.
- W4210555860 cites W2996952711 @default.
- W4210555860 cites W2997511599 @default.
- W4210555860 cites W3000218889 @default.
- W4210555860 cites W3004650169 @default.
- W4210555860 cites W3011872339 @default.
- W4210555860 cites W3024699864 @default.
- W4210555860 cites W3033922476 @default.
- W4210555860 cites W3036482385 @default.
- W4210555860 cites W3044500040 @default.
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- W4210555860 doi "https://doi.org/10.1021/acsami.1c23631" @default.
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