FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4210588045> ?p ?o ?g. }

• W4210588045 abstract "Background: Anti-PD-1/PD-L1 immunotherapy has achieved impressive responses in multiple types of malignancies in recent years. However, immune-related adverse events (irAEs) occur and limit their continuous clinical use. Among these irAEs, acquired amegakaryocytic thrombocytopenia (AAT) is rare but often clinically serious, life-threatening and refractory to multiple treatment approaches. Case summary: We reported for the first time the successful treatment of avatrombopag in two cases of anti-PD1 antibody-induced AAT (in particular, one case had progressed to aplastic anemia), which was refractory or intolerant to glucocorticoids, ciclosporin, intravenous immunoglobulin (IVIG), recombinant human thrombopoietin (rh-TPO) and even TPO receptor agonist (TPO-RA) eltrombopag. To date, the two cases manifested as normal platelet counts and are independent of transfusion. Conclusion: Anti-PD1 antibody-induced AAT occurs with low frequency but is often serious and difficult to manage, for which this study proposed vatrombopag as a potential curative and safe approach." @default.
• W4210588045 created "2022-02-08" @default.
• W4210588045 creator A5000797820 @default.
• W4210588045 creator A5024943157 @default.
• W4210588045 creator A5038386850 @default.
• W4210588045 creator A5049341927 @default.
• W4210588045 creator A5066815620 @default.
• W4210588045 creator A5067411110 @default.
• W4210588045 date "2022-01-27" @default.
• W4210588045 modified "2023-10-14" @default.
• W4210588045 title "Case Report: Successful Avatrombopag Treatment for Two Cases of Anti-PD-1 Antibody-Induced Acquired Amegakaryocytic Thrombocytopenia" @default.
• W4210588045 cites W2009136525 @default.
• W4210588045 cites W2034894117 @default.
• W4210588045 cites W2059190713 @default.
• W4210588045 cites W2084195344 @default.
• W4210588045 cites W2085593142 @default.
• W4210588045 cites W2106339572 @default.
• W4210588045 cites W2594042408 @default.
• W4210588045 cites W2740696595 @default.
• W4210588045 cites W2783623679 @default.
• W4210588045 cites W2818367572 @default.
• W4210588045 cites W2826647829 @default.
• W4210588045 cites W2890360973 @default.
• W4210588045 cites W2899880294 @default.
• W4210588045 cites W2900724115 @default.
• W4210588045 cites W2902822641 @default.
• W4210588045 cites W2946948619 @default.
• W4210588045 cites W2980687050 @default.
• W4210588045 cites W3022093612 @default.
• W4210588045 cites W3120843647 @default.
• W4210588045 cites W3176574681 @default.
• W4210588045 cites W3185682299 @default.
• W4210588045 cites W4211106014 @default.
• W4210588045 cites W4233356231 @default.
• W4210588045 cites W73031340 @default.
• W4210588045 doi "https://doi.org/10.3389/fphar.2021.795884" @default.
• W4210588045 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35153753" @default.
• W4210588045 hasPublicationYear "2022" @default.
• W4210588045 type Work @default.
• W4210588045 citedByCount "3" @default.
• W4210588045 countsByYear W42105880452022 @default.
• W4210588045 countsByYear W42105880452023 @default.
• W4210588045 crossrefType "journal-article" @default.
• W4210588045 hasAuthorship W4210588045A5000797820 @default.
• W4210588045 hasAuthorship W4210588045A5024943157 @default.
• W4210588045 hasAuthorship W4210588045A5038386850 @default.
• W4210588045 hasAuthorship W4210588045A5049341927 @default.
• W4210588045 hasAuthorship W4210588045A5066815620 @default.
• W4210588045 hasAuthorship W4210588045A5067411110 @default.
• W4210588045 hasBestOaLocation W42105880451 @default.
• W4210588045 hasConcept C109159458 @default.
• W4210588045 hasConcept C121332964 @default.
• W4210588045 hasConcept C126322002 @default.
• W4210588045 hasConcept C142424586 @default.
• W4210588045 hasConcept C159654299 @default.
• W4210588045 hasConcept C197934379 @default.
• W4210588045 hasConcept C203014093 @default.
• W4210588045 hasConcept C2777422296 @default.
• W4210588045 hasConcept C2777701055 @default.
• W4210588045 hasConcept C2777863708 @default.
• W4210588045 hasConcept C2778248108 @default.
• W4210588045 hasConcept C2778713057 @default.
• W4210588045 hasConcept C2780007613 @default.
• W4210588045 hasConcept C2780588981 @default.
• W4210588045 hasConcept C2781440808 @default.
• W4210588045 hasConcept C28328180 @default.
• W4210588045 hasConcept C2993327898 @default.
• W4210588045 hasConcept C54355233 @default.
• W4210588045 hasConcept C71924100 @default.
• W4210588045 hasConcept C86803240 @default.
• W4210588045 hasConcept C87355193 @default.
• W4210588045 hasConcept C8891405 @default.
• W4210588045 hasConceptScore W4210588045C109159458 @default.
• W4210588045 hasConceptScore W4210588045C121332964 @default.
• W4210588045 hasConceptScore W4210588045C126322002 @default.
• W4210588045 hasConceptScore W4210588045C142424586 @default.
• W4210588045 hasConceptScore W4210588045C159654299 @default.
• W4210588045 hasConceptScore W4210588045C197934379 @default.
• W4210588045 hasConceptScore W4210588045C203014093 @default.
• W4210588045 hasConceptScore W4210588045C2777422296 @default.
• W4210588045 hasConceptScore W4210588045C2777701055 @default.
• W4210588045 hasConceptScore W4210588045C2777863708 @default.
• W4210588045 hasConceptScore W4210588045C2778248108 @default.
• W4210588045 hasConceptScore W4210588045C2778713057 @default.
• W4210588045 hasConceptScore W4210588045C2780007613 @default.
• W4210588045 hasConceptScore W4210588045C2780588981 @default.
• W4210588045 hasConceptScore W4210588045C2781440808 @default.
• W4210588045 hasConceptScore W4210588045C28328180 @default.
• W4210588045 hasConceptScore W4210588045C2993327898 @default.
• W4210588045 hasConceptScore W4210588045C54355233 @default.
• W4210588045 hasConceptScore W4210588045C71924100 @default.
• W4210588045 hasConceptScore W4210588045C86803240 @default.
• W4210588045 hasConceptScore W4210588045C87355193 @default.
• W4210588045 hasConceptScore W4210588045C8891405 @default.
• W4210588045 hasLocation W42105880451 @default.
• W4210588045 hasLocation W42105880452 @default.
• W4210588045 hasLocation W42105880453 @default.
• W4210588045 hasLocation W42105880454 @default.
• W4210588045 hasOpenAccess W4210588045 @default.
• W4210588045 hasPrimaryLocation W42105880451 @default.

• next