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- W4210588136 abstract "Polymorphism, or the ability of a substance to exist in various crystalline structures, was detected in more than 50% of medicinal substances and turned out to be an extremely important factor determining their therapeutic effect. It is the polymorphism of drugs that largely determines their biological activity. The main problem with this is that the most active form of the drug is not always the most stable, which means that over time or if the storage conditions are violated, the substance can go into another polymorphic modification and lose some of its useful properties. In the present work, β-polymorph of glycine was obtained in a stable state by spray drying using glucose as a modifier (8 wt.%. of glycose in glucose/glycine mixture)." @default.
- W4210588136 created "2022-02-08" @default.
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- W4210588136 date "2022-01-01" @default.
- W4210588136 modified "2023-09-25" @default.
- W4210588136 title "Stabilization of metastable polymorphic form of glycine by glucose" @default.
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- W4210588136 doi "https://doi.org/10.1063/5.0069199" @default.
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