Matches in SemOpenAlex for { <https://semopenalex.org/work/W4210632511> ?p ?o ?g. }
Showing items 1 to 51 of
51
with 100 items per page.
- W4210632511 abstract "Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer (1). We performed discovery of genes associated with epithelial ovarian cancer and of the high-grade serous ovarian cancer (HGSC) subtype, using published and public microarray data (2, 3) to compare global gene expression profiles of normal ovary or fallopian tube with that of primary tumors from women diagnosed with epithelial ovarian cancer or HGSC. We identified the gene encoding diacylglycerol kinase beta, DGKB, as among the genes whose expression was most different in epithelial ovarian cancer as compared to the normal fallopian tube. DGKB expression was significantly lower in high-grade serous ovarian tumors relative to normal fallopian tube. DGKB expression correlated with progression-free survival in patients with ovarian cancer. These data indicate that expression of DGKB is perturbed in epithelial ovarian cancers broadly and in ovarian cancers of the HGSC subtype. DGKB may be relevant to pathways underlying ovarian cancer initiation (transformation) or progression." @default.
- W4210632511 created "2022-02-08" @default.
- W4210632511 creator A5024900493 @default.
- W4210632511 date "2021-08-27" @default.
- W4210632511 modified "2023-09-26" @default.
- W4210632511 title "Differential expression of diacylglycerol kinase beta in human epithelial ovarian cancer." @default.
- W4210632511 doi "https://doi.org/10.31219/osf.io/ut98z" @default.
- W4210632511 hasPublicationYear "2021" @default.
- W4210632511 type Work @default.
- W4210632511 citedByCount "0" @default.
- W4210632511 crossrefType "posted-content" @default.
- W4210632511 hasAuthorship W4210632511A5024900493 @default.
- W4210632511 hasBestOaLocation W42106325111 @default.
- W4210632511 hasConcept C121608353 @default.
- W4210632511 hasConcept C126322002 @default.
- W4210632511 hasConcept C143998085 @default.
- W4210632511 hasConcept C150173356 @default.
- W4210632511 hasConcept C2775883341 @default.
- W4210632511 hasConcept C2778324911 @default.
- W4210632511 hasConcept C2780427987 @default.
- W4210632511 hasConcept C29456083 @default.
- W4210632511 hasConcept C502942594 @default.
- W4210632511 hasConcept C71924100 @default.
- W4210632511 hasConcept C86803240 @default.
- W4210632511 hasConceptScore W4210632511C121608353 @default.
- W4210632511 hasConceptScore W4210632511C126322002 @default.
- W4210632511 hasConceptScore W4210632511C143998085 @default.
- W4210632511 hasConceptScore W4210632511C150173356 @default.
- W4210632511 hasConceptScore W4210632511C2775883341 @default.
- W4210632511 hasConceptScore W4210632511C2778324911 @default.
- W4210632511 hasConceptScore W4210632511C2780427987 @default.
- W4210632511 hasConceptScore W4210632511C29456083 @default.
- W4210632511 hasConceptScore W4210632511C502942594 @default.
- W4210632511 hasConceptScore W4210632511C71924100 @default.
- W4210632511 hasConceptScore W4210632511C86803240 @default.
- W4210632511 hasLocation W42106325111 @default.
- W4210632511 hasOpenAccess W4210632511 @default.
- W4210632511 hasPrimaryLocation W42106325111 @default.
- W4210632511 hasRelatedWork W1526602731 @default.
- W4210632511 hasRelatedWork W2063654850 @default.
- W4210632511 hasRelatedWork W2128458428 @default.
- W4210632511 hasRelatedWork W2164916859 @default.
- W4210632511 hasRelatedWork W2167493426 @default.
- W4210632511 hasRelatedWork W2486090949 @default.
- W4210632511 hasRelatedWork W2518043106 @default.
- W4210632511 hasRelatedWork W2791963911 @default.
- W4210632511 hasRelatedWork W2986123162 @default.
- W4210632511 hasRelatedWork W4200548595 @default.
- W4210632511 isParatext "false" @default.
- W4210632511 isRetracted "false" @default.
- W4210632511 workType "article" @default.