Matches in SemOpenAlex for { <https://semopenalex.org/work/W4210639129> ?p ?o ?g. }
- W4210639129 endingPage "287" @default.
- W4210639129 startingPage "287" @default.
- W4210639129 abstract "The objective of this study was to provide information on Trypanosoma cruzi genetic diversity among isolates obtained from different biological sources circulating in endemic areas of Panama. Initial discrete typing units (DTUs) assignment was performed evaluating three single locus molecular markers (mini-exon, heat shock protein 60 and glucose-6-phosphate isomerase genes). Further diversity within TcI lineages was explored using a multi-locus sequence typing approach with six maxicircle genes. Haplotype network analysis and evolutionary divergency estimations were conducted to investigate the genetic relatedness between Panamanian TcI isolates and isolates from different endemic regions in the Americas. Our molecular approach validated that TcI is the predominant DTU circulating in Panama across different hosts and vector species, but also confirmed the presence of TcIII and TcVI circulating in the country. The phylogenetic tree topography for most Panamanian TcI isolates displayed a high level of genetic homogeneity between them. The haplotype network analysis inferred a higher genetic diversity within Panamanian TcI isolates, displaying eight different haplotypes circulating in endemic regions of the country, and revealed geographical structuring among TcI from different endemic regions in the Americas. This study adds novelty on the genetic diversity of T. cruzi circulating in Panama and complements regional phylogeographic studies regarding intra-TcI variations." @default.
- W4210639129 created "2022-02-08" @default.
- W4210639129 creator A5006859346 @default.
- W4210639129 creator A5044804416 @default.
- W4210639129 creator A5045875822 @default.
- W4210639129 creator A5049947842 @default.
- W4210639129 creator A5087416696 @default.
- W4210639129 creator A5089473711 @default.
- W4210639129 date "2022-01-26" @default.
- W4210639129 modified "2023-10-01" @default.
- W4210639129 title "Genetic Diversity of Trypanosoma cruzi in Panama Inferred by Multi-locus Sequence Typing of Mitochondrial Genes" @default.
- W4210639129 cites W1712511248 @default.
- W4210639129 cites W1913569407 @default.
- W4210639129 cites W1969042907 @default.
- W4210639129 cites W1979269423 @default.
- W4210639129 cites W1979692840 @default.
- W4210639129 cites W1986623547 @default.
- W4210639129 cites W1992358589 @default.
- W4210639129 cites W2002393058 @default.
- W4210639129 cites W2006139571 @default.
- W4210639129 cites W2007686520 @default.
- W4210639129 cites W2010370596 @default.
- W4210639129 cites W2017619866 @default.
- W4210639129 cites W2019755015 @default.
- W4210639129 cites W2042247311 @default.
- W4210639129 cites W2051116265 @default.
- W4210639129 cites W2059134652 @default.
- W4210639129 cites W2061246349 @default.
- W4210639129 cites W2061833769 @default.
- W4210639129 cites W2068741596 @default.
- W4210639129 cites W2071895358 @default.
- W4210639129 cites W2075939822 @default.
- W4210639129 cites W2087320520 @default.
- W4210639129 cites W2093632823 @default.
- W4210639129 cites W2097661684 @default.
- W4210639129 cites W2098466396 @default.
- W4210639129 cites W2110036731 @default.
- W4210639129 cites W2123308799 @default.
- W4210639129 cites W2125295153 @default.
- W4210639129 cites W2129392035 @default.
- W4210639129 cites W2132504826 @default.
- W4210639129 cites W2144617503 @default.
- W4210639129 cites W2149258299 @default.
- W4210639129 cites W2151551515 @default.
- W4210639129 cites W2153164685 @default.
- W4210639129 cites W2157259731 @default.
- W4210639129 cites W2166319880 @default.
- W4210639129 cites W2172105162 @default.
- W4210639129 cites W2183584132 @default.
- W4210639129 cites W2409855746 @default.
- W4210639129 cites W2410520076 @default.
- W4210639129 cites W2412954172 @default.
- W4210639129 cites W2466973729 @default.
- W4210639129 cites W2513988271 @default.
- W4210639129 cites W2516907192 @default.
- W4210639129 cites W2522217822 @default.
- W4210639129 cites W2757157006 @default.
- W4210639129 cites W2758463746 @default.
- W4210639129 cites W2762263940 @default.
- W4210639129 cites W2792568060 @default.
- W4210639129 cites W2799524357 @default.
- W4210639129 cites W2807655819 @default.
- W4210639129 cites W2884776343 @default.
- W4210639129 cites W2912758200 @default.
- W4210639129 cites W2925538549 @default.
- W4210639129 cites W2939365660 @default.
- W4210639129 cites W2965799332 @default.
- W4210639129 cites W3013311833 @default.
- W4210639129 cites W3092063858 @default.
- W4210639129 cites W3104798302 @default.
- W4210639129 cites W3131534030 @default.
- W4210639129 cites W3132731937 @default.
- W4210639129 cites W3134317746 @default.
- W4210639129 cites W3169669690 @default.
- W4210639129 cites W3194975773 @default.
- W4210639129 cites W3195212533 @default.
- W4210639129 cites W3206754041 @default.
- W4210639129 cites W4205518260 @default.
- W4210639129 cites W4213175661 @default.
- W4210639129 cites W4313465027 @default.
- W4210639129 cites W924701749 @default.
- W4210639129 doi "https://doi.org/10.3390/microorganisms10020287" @default.
- W4210639129 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35208746" @default.
- W4210639129 hasPublicationYear "2022" @default.
- W4210639129 type Work @default.
- W4210639129 citedByCount "2" @default.
- W4210639129 countsByYear W42106391292022 @default.
- W4210639129 countsByYear W42106391292023 @default.
- W4210639129 crossrefType "journal-article" @default.
- W4210639129 hasAuthorship W4210639129A5006859346 @default.
- W4210639129 hasAuthorship W4210639129A5044804416 @default.
- W4210639129 hasAuthorship W4210639129A5045875822 @default.
- W4210639129 hasAuthorship W4210639129A5049947842 @default.
- W4210639129 hasAuthorship W4210639129A5087416696 @default.
- W4210639129 hasAuthorship W4210639129A5089473711 @default.
- W4210639129 hasBestOaLocation W42106391291 @default.
- W4210639129 hasConcept C104317684 @default.
- W4210639129 hasConcept C135763542 @default.