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- W4210755039 abstract "The objective of the different types of treatments for a spinal metastasis is to provide the best oncological and functional result with the least aggressive side effects. Initially created in 2010 to help clinicians in the management of vertebral metastases, the Spine Instability Neoplastic Score (SINS) has quickly found its place in the decision making and the treatment of patients with metastatic spinal disease. Here we conduct a review of the literature describing the different changes that occurred with the SINS score in the last ten years. After a brief presentation of the spinal metastases' distribution, with or without spinal cord compression, we present the utility of SINS in the radiological diagnosis and extension of the disease, in addition to its limits, especially for scores ranging between 7 and 12. We take this opportunity to expose the latest advances in surgery and radiotherapy concerning spinal metastases, as well as in palliative care and pain control. We also discuss the reliability of SINS amongst radiologists, radiation oncologists, spine surgeons and spine surgery trainees. Finally, we will present the new SINS-derived predictive scores, biomarkers and artificial intelligence algorithms that allow a multidisciplinary approach for the management of spinal metastases." @default.
- W4210755039 created "2022-02-08" @default.
- W4210755039 creator A5002382102 @default.
- W4210755039 creator A5008125625 @default.
- W4210755039 creator A5023525356 @default.
- W4210755039 creator A5045566405 @default.
- W4210755039 creator A5057573029 @default.
- W4210755039 creator A5058115332 @default.
- W4210755039 creator A5059304848 @default.
- W4210755039 date "2022-01-27" @default.
- W4210755039 modified "2023-10-14" @default.
- W4210755039 title "Ten Years After SINS: Role of Surgery and Radiotherapy in the Management of Patients With Vertebral Metastases" @default.
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