Matches in SemOpenAlex for { <https://semopenalex.org/work/W4210784857> ?p ?o ?g. }
- W4210784857 endingPage "112384" @default.
- W4210784857 startingPage "112384" @default.
- W4210784857 abstract "Biomembranes are involved in diverse cellular activities. How membranes and proteins interact in the activities might hinge on the former's physical characteristics, which in turn are influenced by packing of lipid molecules. Yet, the validity of this understanding and its mechanism are unclear. By varying chain saturation of membranes, we explored correlations between lipid packing and peptide-mediated membrane disruption for the antimicrobial peptide, melittin, and amyloidogenic peptide, β-amyloid (1-42). Remarkably, reducing molecular packing flexibility enhanced the membrane disruption, possibly due to a shift from membrane perforation to micellization. A theoretical analysis suggested the energetic basis of this shift. This mechanistically shows that a peptide's mechanism might be dictated not only by its intrinsic properties but also by physical characteristics of membranes." @default.
- W4210784857 created "2022-02-08" @default.
- W4210784857 creator A5012321811 @default.
- W4210784857 creator A5038461157 @default.
- W4210784857 creator A5054510529 @default.
- W4210784857 creator A5077062450 @default.
- W4210784857 date "2022-05-01" @default.
- W4210784857 modified "2023-09-26" @default.
- W4210784857 title "Molecular packing of lipid membranes and action mechanisms of membrane-active peptides" @default.
- W4210784857 cites W1580480113 @default.
- W4210784857 cites W1966778905 @default.
- W4210784857 cites W1973817630 @default.
- W4210784857 cites W1981984118 @default.
- W4210784857 cites W1989948422 @default.
- W4210784857 cites W1989970156 @default.
- W4210784857 cites W1993562651 @default.
- W4210784857 cites W1998692503 @default.
- W4210784857 cites W2005315703 @default.
- W4210784857 cites W2015484447 @default.
- W4210784857 cites W2034214429 @default.
- W4210784857 cites W2035367268 @default.
- W4210784857 cites W2035557563 @default.
- W4210784857 cites W2036020441 @default.
- W4210784857 cites W2041282850 @default.
- W4210784857 cites W2043773809 @default.
- W4210784857 cites W2057653477 @default.
- W4210784857 cites W2058258523 @default.
- W4210784857 cites W2063808031 @default.
- W4210784857 cites W2073522893 @default.
- W4210784857 cites W2076601910 @default.
- W4210784857 cites W2077438184 @default.
- W4210784857 cites W2079205673 @default.
- W4210784857 cites W2080225612 @default.
- W4210784857 cites W2091514612 @default.
- W4210784857 cites W2091617831 @default.
- W4210784857 cites W2093290512 @default.
- W4210784857 cites W2105704879 @default.
- W4210784857 cites W2105852321 @default.
- W4210784857 cites W2118935254 @default.
- W4210784857 cites W2131295615 @default.
- W4210784857 cites W2134909516 @default.
- W4210784857 cites W2138226073 @default.
- W4210784857 cites W2149453359 @default.
- W4210784857 cites W2171115266 @default.
- W4210784857 cites W2229781928 @default.
- W4210784857 cites W2329336071 @default.
- W4210784857 cites W2363718671 @default.
- W4210784857 cites W2403862021 @default.
- W4210784857 cites W2464369392 @default.
- W4210784857 cites W2509048507 @default.
- W4210784857 cites W2512495197 @default.
- W4210784857 cites W2516510864 @default.
- W4210784857 cites W2519805918 @default.
- W4210784857 cites W2613271410 @default.
- W4210784857 cites W2614053601 @default.
- W4210784857 cites W2730334649 @default.
- W4210784857 cites W2736908165 @default.
- W4210784857 cites W2747365677 @default.
- W4210784857 cites W2773490123 @default.
- W4210784857 cites W2781210800 @default.
- W4210784857 cites W2791111928 @default.
- W4210784857 cites W2809078375 @default.
- W4210784857 cites W2908547452 @default.
- W4210784857 cites W2910766400 @default.
- W4210784857 cites W2917512848 @default.
- W4210784857 cites W2937132049 @default.
- W4210784857 cites W2946968312 @default.
- W4210784857 cites W2964111426 @default.
- W4210784857 cites W2974542619 @default.
- W4210784857 cites W3017269697 @default.
- W4210784857 cites W3113423949 @default.
- W4210784857 cites W4247759744 @default.
- W4210784857 doi "https://doi.org/10.1016/j.colsurfb.2022.112384" @default.
- W4210784857 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35151994" @default.
- W4210784857 hasPublicationYear "2022" @default.
- W4210784857 type Work @default.
- W4210784857 citedByCount "1" @default.
- W4210784857 countsByYear W42107848572023 @default.
- W4210784857 crossrefType "journal-article" @default.
- W4210784857 hasAuthorship W4210784857A5012321811 @default.
- W4210784857 hasAuthorship W4210784857A5038461157 @default.
- W4210784857 hasAuthorship W4210784857A5054510529 @default.
- W4210784857 hasAuthorship W4210784857A5077062450 @default.
- W4210784857 hasConcept C12554922 @default.
- W4210784857 hasConcept C185592680 @default.
- W4210784857 hasConcept C2778001312 @default.
- W4210784857 hasConcept C2779281246 @default.
- W4210784857 hasConcept C39944091 @default.
- W4210784857 hasConcept C41625074 @default.
- W4210784857 hasConcept C540938839 @default.
- W4210784857 hasConcept C55493867 @default.
- W4210784857 hasConcept C86803240 @default.
- W4210784857 hasConceptScore W4210784857C12554922 @default.
- W4210784857 hasConceptScore W4210784857C185592680 @default.
- W4210784857 hasConceptScore W4210784857C2778001312 @default.
- W4210784857 hasConceptScore W4210784857C2779281246 @default.
- W4210784857 hasConceptScore W4210784857C39944091 @default.
- W4210784857 hasConceptScore W4210784857C41625074 @default.