FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4210844333> ?p ?o ?g. }

• W4210844333 endingPage "445" @default.
• W4210844333 startingPage "434" @default.
• W4210844333 abstract "Purpose: We aimed to evaluate whether CEMIP plays any role in the survival outcome of breast cancer (BC) patients, as well as to explore the regulatory mechanism of CEMIP in BC. Methods: We evaluated the expression and prognostic effect of CEMIP in BC patients using the Oncomine, GEPIA, UALCAN, and Kaplan-Meier plotter databases. Additionally, we detected CEMIP mRNA and protein levels in BC and normal tissues via PCR and western blotting analyses. Through immunochemistry analysis, we quantified CEMIP expression in 233 samples from BC patients. We then analyzed the link between the survival outcomes and CEMIP expression based on these clinical samples. Furthermore, we explored the immune-related molecules regulated by CEMIP and its coexpressed genes using the STRING database. Results: CEMIP expression was higher in BC tissues than in normal tissues. Patients with high CEMIP mRNA levels had a worse survival outcome. Similarly, patients expressing CEMIP had significantly shorter overall survival and disease-free survival than those not expressing the protein (P < 0.01). Some lymphocytes, immune inhibitors, immune stimulators, MHC molecules, chemokines, and chemokine receptors can be regulated by CEMIP, and CEMIP and its coexpressed genes can participate in the hyaluronan biosynthetic process, hyaluronan catabolic process, and other related biological processes in the progression of BC. Conclusion: Compared to normal tissues, BC tissues had higher number of CEMIP transcripts. CEMIP expression was associated with an adverse prognosis. CEMIP and its coexpressed genes can participate in the progression of BC. Therefore, CEMIP may be a potential biomarker for the treatment of BC patients." @default.
• W4210844333 created "2022-02-09" @default.
• W4210844333 creator A5000989655 @default.
• W4210844333 creator A5026107610 @default.
• W4210844333 creator A5029148942 @default.
• W4210844333 creator A5052629282 @default.
• W4210844333 creator A5054771846 @default.
• W4210844333 creator A5055551987 @default.
• W4210844333 creator A5056692565 @default.
• W4210844333 creator A5077998630 @default.
• W4210844333 creator A5082213642 @default.
• W4210844333 creator A5086514660 @default.
• W4210844333 date "2022-01-01" @default.
• W4210844333 modified "2023-10-17" @default.
• W4210844333 title "<i>CEMIP</i> as a potential biomarker and therapeutic target for breast cancer patients" @default.
• W4210844333 cites W1975313118 @default.
• W4210844333 cites W2005895632 @default.
• W4210844333 cites W2021884121 @default.
• W4210844333 cites W2027092476 @default.
• W4210844333 cites W2036452381 @default.
• W4210844333 cites W2075500360 @default.
• W4210844333 cites W2080337585 @default.
• W4210844333 cites W2082668371 @default.
• W4210844333 cites W2085934079 @default.
• W4210844333 cites W2101487034 @default.
• W4210844333 cites W2105393937 @default.
• W4210844333 cites W2114441824 @default.
• W4210844333 cites W2116859091 @default.
• W4210844333 cites W2126810305 @default.
• W4210844333 cites W2149441684 @default.
• W4210844333 cites W2154514624 @default.
• W4210844333 cites W2179344918 @default.
• W4210844333 cites W2346893740 @default.
• W4210844333 cites W2414449891 @default.
• W4210844333 cites W2510248262 @default.
• W4210844333 cites W2565559107 @default.
• W4210844333 cites W2583541113 @default.
• W4210844333 cites W2588560205 @default.
• W4210844333 cites W2594727603 @default.
• W4210844333 cites W2605898399 @default.
• W4210844333 cites W2736730167 @default.
• W4210844333 cites W2794045676 @default.
• W4210844333 cites W2794165689 @default.
• W4210844333 cites W2808293799 @default.
• W4210844333 cites W2889646458 @default.
• W4210844333 cites W2900809514 @default.
• W4210844333 cites W2923414107 @default.
• W4210844333 cites W2936480426 @default.
• W4210844333 cites W2937441321 @default.
• W4210844333 cites W3047200528 @default.
• W4210844333 doi "https://doi.org/10.7150/ijms.58067" @default.
• W4210844333 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35370456" @default.
• W4210844333 hasPublicationYear "2022" @default.
• W4210844333 type Work @default.
• W4210844333 citedByCount "4" @default.
• W4210844333 countsByYear W42108443332022 @default.
• W4210844333 countsByYear W42108443332023 @default.
• W4210844333 crossrefType "journal-article" @default.
• W4210844333 hasAuthorship W4210844333A5000989655 @default.
• W4210844333 hasAuthorship W4210844333A5026107610 @default.
• W4210844333 hasAuthorship W4210844333A5029148942 @default.
• W4210844333 hasAuthorship W4210844333A5052629282 @default.
• W4210844333 hasAuthorship W4210844333A5054771846 @default.
• W4210844333 hasAuthorship W4210844333A5055551987 @default.
• W4210844333 hasAuthorship W4210844333A5056692565 @default.
• W4210844333 hasAuthorship W4210844333A5077998630 @default.
• W4210844333 hasAuthorship W4210844333A5082213642 @default.
• W4210844333 hasAuthorship W4210844333A5086514660 @default.
• W4210844333 hasBestOaLocation W42108443331 @default.
• W4210844333 hasConcept C10515644 @default.
• W4210844333 hasConcept C121608353 @default.
• W4210844333 hasConcept C126322002 @default.
• W4210844333 hasConcept C13373296 @default.
• W4210844333 hasConcept C143998085 @default.
• W4210844333 hasConcept C203014093 @default.
• W4210844333 hasConcept C2781197716 @default.
• W4210844333 hasConcept C502942594 @default.
• W4210844333 hasConcept C530470458 @default.
• W4210844333 hasConcept C54355233 @default.
• W4210844333 hasConcept C71924100 @default.
• W4210844333 hasConcept C86803240 @default.
• W4210844333 hasConcept C8891405 @default.
• W4210844333 hasConceptScore W4210844333C10515644 @default.
• W4210844333 hasConceptScore W4210844333C121608353 @default.
• W4210844333 hasConceptScore W4210844333C126322002 @default.
• W4210844333 hasConceptScore W4210844333C13373296 @default.
• W4210844333 hasConceptScore W4210844333C143998085 @default.
• W4210844333 hasConceptScore W4210844333C203014093 @default.
• W4210844333 hasConceptScore W4210844333C2781197716 @default.
• W4210844333 hasConceptScore W4210844333C502942594 @default.
• W4210844333 hasConceptScore W4210844333C530470458 @default.
• W4210844333 hasConceptScore W4210844333C54355233 @default.
• W4210844333 hasConceptScore W4210844333C71924100 @default.
• W4210844333 hasConceptScore W4210844333C86803240 @default.
• W4210844333 hasConceptScore W4210844333C8891405 @default.
• W4210844333 hasIssue "3" @default.
• W4210844333 hasLocation W42108443331 @default.
• W4210844333 hasLocation W42108443332 @default.

• next