Matches in SemOpenAlex for { <https://semopenalex.org/work/W4210846503> ?p ?o ?g. }
- W4210846503 endingPage "2022" @default.
- W4210846503 startingPage "2010" @default.
- W4210846503 abstract "Atrial fibrillation (AF) is the most common type of persistent arrhythmia. Although its incidence has been increasing, the pathogenesis of AF in stroke remains unclear. In this study, a total of 30 participants were recruited, including 10 controls, 10 patients with AF and 10 patients with AF and stroke (AF + STROKE). Differentially expressed genes (DEGs) were identified, and functional annotation of DEGs, comparative toxicogenomic database analysis associated with cardiovascular diseases, and predictions of miRNAs of hub genes were performed. Using RT-qPCR, biological process and support vector machine neural networks, numerous DEGs were found to be related to AF. HBG1, SNCA and GYPB were found to be upregulated in the AF group. Higher expression of hub genes in AF and AF + STROKE groups was detected via RT-PCR. Upon training the biological process neural network of SNCA and GYPB for HBG1, only small differences were detected. Based on the support vector machine, the predicted value of SNCA and GYPB for HBG1 was 0.9893. Expression of the hub genes of HBG1, SNCA and GYPB might therefore be significantly correlated to AF. These genes are involved in the incidence of AF complicated by stroke, and may serve as targets for early diagnosis and treatment." @default.
- W4210846503 created "2022-02-09" @default.
- W4210846503 creator A5005303388 @default.
- W4210846503 creator A5011492106 @default.
- W4210846503 creator A5019032012 @default.
- W4210846503 creator A5019906827 @default.
- W4210846503 creator A5022212018 @default.
- W4210846503 creator A5046921201 @default.
- W4210846503 creator A5049971270 @default.
- W4210846503 creator A5062394235 @default.
- W4210846503 creator A5064842058 @default.
- W4210846503 date "2022-02-09" @default.
- W4210846503 modified "2023-09-27" @default.
- W4210846503 title "Joint efficacy of the three biomarkers <i>SNCA</i> , <i>GYPB</i> and <i>HBG1</i> for atrial fibrillation and stroke: Analysis via the support vector machine neural network" @default.
- W4210846503 cites W131053648 @default.
- W4210846503 cites W1600313983 @default.
- W4210846503 cites W1975723336 @default.
- W4210846503 cites W1989584376 @default.
- W4210846503 cites W2008450235 @default.
- W4210846503 cites W2015707574 @default.
- W4210846503 cites W2023570989 @default.
- W4210846503 cites W2036449064 @default.
- W4210846503 cites W2038329412 @default.
- W4210846503 cites W2045089303 @default.
- W4210846503 cites W2047592374 @default.
- W4210846503 cites W2053926447 @default.
- W4210846503 cites W205630357 @default.
- W4210846503 cites W2068877594 @default.
- W4210846503 cites W2104475665 @default.
- W4210846503 cites W2106809715 @default.
- W4210846503 cites W2116427214 @default.
- W4210846503 cites W2129906781 @default.
- W4210846503 cites W2132210870 @default.
- W4210846503 cites W2135694398 @default.
- W4210846503 cites W2137088471 @default.
- W4210846503 cites W2138572847 @default.
- W4210846503 cites W2139331374 @default.
- W4210846503 cites W2141889414 @default.
- W4210846503 cites W2145965840 @default.
- W4210846503 cites W2147018083 @default.
- W4210846503 cites W2156033452 @default.
- W4210846503 cites W2201952379 @default.
- W4210846503 cites W2234265243 @default.
- W4210846503 cites W2293224520 @default.
- W4210846503 cites W2334263927 @default.
- W4210846503 cites W2474938401 @default.
- W4210846503 cites W2509795914 @default.
- W4210846503 cites W2611063366 @default.
- W4210846503 cites W2739742752 @default.
- W4210846503 cites W2742923212 @default.
- W4210846503 cites W2765742885 @default.
- W4210846503 cites W2790894106 @default.
- W4210846503 cites W2896667788 @default.
- W4210846503 cites W2896796940 @default.
- W4210846503 cites W2900656286 @default.
- W4210846503 cites W2947214669 @default.
- W4210846503 cites W2953039392 @default.
- W4210846503 cites W2971609214 @default.
- W4210846503 cites W2994578305 @default.
- W4210846503 cites W3004050106 @default.
- W4210846503 cites W3017113604 @default.
- W4210846503 cites W3025364931 @default.
- W4210846503 cites W3096480242 @default.
- W4210846503 cites W3117546748 @default.
- W4210846503 cites W3134662101 @default.
- W4210846503 cites W3184715852 @default.
- W4210846503 cites W4210846503 @default.
- W4210846503 cites W4211119300 @default.
- W4210846503 cites W4296277331 @default.
- W4210846503 doi "https://doi.org/10.1111/jcmm.17224" @default.
- W4210846503 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35138035" @default.
- W4210846503 hasPublicationYear "2022" @default.
- W4210846503 type Work @default.
- W4210846503 citedByCount "4" @default.
- W4210846503 countsByYear W42108465032022 @default.
- W4210846503 countsByYear W42108465032023 @default.
- W4210846503 crossrefType "journal-article" @default.
- W4210846503 hasAuthorship W4210846503A5005303388 @default.
- W4210846503 hasAuthorship W4210846503A5011492106 @default.
- W4210846503 hasAuthorship W4210846503A5019032012 @default.
- W4210846503 hasAuthorship W4210846503A5019906827 @default.
- W4210846503 hasAuthorship W4210846503A5022212018 @default.
- W4210846503 hasAuthorship W4210846503A5046921201 @default.
- W4210846503 hasAuthorship W4210846503A5049971270 @default.
- W4210846503 hasAuthorship W4210846503A5062394235 @default.
- W4210846503 hasAuthorship W4210846503A5064842058 @default.
- W4210846503 hasBestOaLocation W42108465031 @default.
- W4210846503 hasConcept C104317684 @default.
- W4210846503 hasConcept C120665830 @default.
- W4210846503 hasConcept C121332964 @default.
- W4210846503 hasConcept C126322002 @default.
- W4210846503 hasConcept C127413603 @default.
- W4210846503 hasConcept C164705383 @default.
- W4210846503 hasConcept C2779161974 @default.
- W4210846503 hasConcept C2780645631 @default.
- W4210846503 hasConcept C54355233 @default.
- W4210846503 hasConcept C60644358 @default.
- W4210846503 hasConcept C61511704 @default.