FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4210882004> ?p ?o ?g. }

• W4210882004 endingPage "3" @default.
• W4210882004 startingPage "1" @default.
• W4210882004 abstract "A 66-year-old Caucasian woman presented to the dermatology department with complaints of a pigmented lesion on the left shin. She first noticed the lesion in March 2020, several months prior to presentation but decided to seek medical advice after observing substantial growth in the size and shape of the lesion. She was diagnosed with type II arterial hypertension 6 years ago and was started losartan/hydrochlorothiazide 50 mg / 12.5mg half a tablet daily. The patient visits her general practitioner regularly and her hypertension is well controlled on these medications, had no other concomitant diseases and was relatively healthy for her age. No family history for dermatologic diseases was available. On dermatologic examination, a single superficially spreading pretibial lesion covering 1.8 cm wide and 1.2cm high was noted(Figure 1a). The light greyish-pink pigmented lesion was oval in shape with sharply demarcated borders and no elevation above the surrounding skin. Further laboratory work-up showed no signs of deviations. Based on the clinical and dermatoscopic evidence, the diagnosis of melanoma in situ, lentigo maligna type was made. She was sent for treatment at a specialised hospital for oncological diseases in June 2020 where a surgical excision was performed under local anaesthesia with 0.5cm clear/ negative margins in all directions. The defect was thereafter closed using a full-thickness mesh graft taken from the abdominal region(Figure 1b). The excised tumour was subsequently sent for histological evaluation and was keeping with the clinicopathological diagnosis of lentigo maligna. Immunohistochemical analysis also identified S100 positive nests of cells within the basal lamina, confirming the diagnosis.Postsurgical wound healing with the skin graft was poor due to inadequate graft transplantation whereby necrotic as well as macerated areas were observed leadingto bad cosmetic results (Figure 1c-h).After a multidisciplinary review and follow up, a second operation was performed a month later to remove the necrotic, together with the hypertrophic tissue and a new split skin mesh graft was utilised. Stringent post-operative care, including prophylactic antibiotic therapy was also provided to promote good wound healing which was achieved several months later (Figure 1i)." @default.
• W4210882004 created "2022-02-09" @default.
• W4210882004 creator A5048607958 @default.
• W4210882004 creator A5056648284 @default.
• W4210882004 creator A5069509866 @default.
• W4210882004 creator A5089367377 @default.
• W4210882004 date "2021-08-21" @default.
• W4210882004 modified "2023-10-16" @default.
• W4210882004 title "Nitrosamine (and /or Losartan/ Hydrochlorothiazide) Induced Pretibial Located Lentigo Maligna: First Reported Case in the World Literature" @default.
• W4210882004 doi "https://doi.org/10.15226/2378-1726/8/3/001143" @default.
• W4210882004 hasPublicationYear "2021" @default.
• W4210882004 type Work @default.
• W4210882004 citedByCount "0" @default.
• W4210882004 crossrefType "journal-article" @default.
• W4210882004 hasAuthorship W4210882004A5048607958 @default.
• W4210882004 hasAuthorship W4210882004A5056648284 @default.
• W4210882004 hasAuthorship W4210882004A5069509866 @default.
• W4210882004 hasAuthorship W4210882004A5089367377 @default.
• W4210882004 hasBestOaLocation W42108820041 @default.
• W4210882004 hasConcept C126838900 @default.
• W4210882004 hasConcept C141071460 @default.
• W4210882004 hasConcept C142724271 @default.
• W4210882004 hasConcept C16005928 @default.
• W4210882004 hasConcept C2775932916 @default.
• W4210882004 hasConcept C2777197935 @default.
• W4210882004 hasConcept C2777393561 @default.
• W4210882004 hasConcept C2777658100 @default.
• W4210882004 hasConcept C2779384505 @default.
• W4210882004 hasConcept C2780361556 @default.
• W4210882004 hasConcept C2781156865 @default.
• W4210882004 hasConcept C502942594 @default.
• W4210882004 hasConcept C71924100 @default.
• W4210882004 hasConcept C84393581 @default.
• W4210882004 hasConceptScore W4210882004C126838900 @default.
• W4210882004 hasConceptScore W4210882004C141071460 @default.
• W4210882004 hasConceptScore W4210882004C142724271 @default.
• W4210882004 hasConceptScore W4210882004C16005928 @default.
• W4210882004 hasConceptScore W4210882004C2775932916 @default.
• W4210882004 hasConceptScore W4210882004C2777197935 @default.
• W4210882004 hasConceptScore W4210882004C2777393561 @default.
• W4210882004 hasConceptScore W4210882004C2777658100 @default.
• W4210882004 hasConceptScore W4210882004C2779384505 @default.
• W4210882004 hasConceptScore W4210882004C2780361556 @default.
• W4210882004 hasConceptScore W4210882004C2781156865 @default.
• W4210882004 hasConceptScore W4210882004C502942594 @default.
• W4210882004 hasConceptScore W4210882004C71924100 @default.
• W4210882004 hasConceptScore W4210882004C84393581 @default.
• W4210882004 hasIssue "3" @default.
• W4210882004 hasLocation W42108820041 @default.
• W4210882004 hasOpenAccess W4210882004 @default.
• W4210882004 hasPrimaryLocation W42108820041 @default.
• W4210882004 hasRelatedWork W1984257646 @default.
• W4210882004 hasRelatedWork W2076304420 @default.
• W4210882004 hasRelatedWork W2078684683 @default.
• W4210882004 hasRelatedWork W2151568833 @default.
• W4210882004 hasRelatedWork W2979688752 @default.
• W4210882004 hasRelatedWork W3016727668 @default.
• W4210882004 hasRelatedWork W4210872374 @default.
• W4210882004 hasRelatedWork W4210882004 @default.
• W4210882004 hasRelatedWork W4243226233 @default.
• W4210882004 hasRelatedWork W763936232 @default.
• W4210882004 hasVolume "8" @default.
• W4210882004 isParatext "false" @default.
• W4210882004 isRetracted "false" @default.
• W4210882004 workType "article" @default.