FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4210910366> ?p ?o ?g. }

• W4210910366 abstract "The Acuitas antimicrobial resistance (AMR) gene panel is a qualitative, multiplex, nucleic acid-based in vitro diagnostic test for the detection and differentiation of 28 antimicrobial resistance markers associated with not susceptible results (NS; i.e., intermediate or resistant) to one or more antimicrobial agents among cultured isolates of select Enterobacterales, Pseudomonas aeruginosa, and Enterococcus faecalis. This study was conducted at four sites and included testing of 1,224 deidentified stocks created from 584 retrospectively collected isolates and 83 prospectively collected clinical isolates. The Acuitas results were compared with a combined reference standard including whole-genome sequencing, organism identification, and phenotypic antimicrobial susceptibility testing. The positive percent agreement (PPA) for FDA-cleared AMR targets ranged from 94.4% for MCR-1 to 100% for armA, CTX-M-2, DHA, IMP, OXA-9, SHV, vanA, and VEB. The negative percent agreement (NPA) for the majority of targets was ≥99%, except for AAC, AAD, CMY-41, P. aeruginosa gyrA mutant, Sul1, Sul2, and TEM targets (range, 96.5% to 98.5%). Three AMR markers did not meet FDA inclusion criteria (GES, SPM, and MCR-2). For each organism, 1 to 22 AMR targets met the minimum reportable PPA/NPA and correlated with ≥80% positive predictive value with associated NS results for at least one agent (i.e., the probability of an organism carrying an AMR marker testing NS to the associated agent). We demonstrate that the Acuitas AMR gene panel is an accurate method to detect a broad array of AMR markers among cultured isolates. The AMR markers were further associated with expected NS results for specific agent-organism combinations." @default.
• W4210910366 created "2022-02-09" @default.
• W4210910366 creator A5001896973 @default.
• W4210910366 creator A5011640815 @default.
• W4210910366 creator A5013216983 @default.
• W4210910366 creator A5025055624 @default.
• W4210910366 creator A5027534791 @default.
• W4210910366 creator A5037546003 @default.
• W4210910366 creator A5044556184 @default.
• W4210910366 creator A5045120202 @default.
• W4210910366 creator A5047176330 @default.
• W4210910366 creator A5055687038 @default.
• W4210910366 creator A5057106696 @default.
• W4210910366 creator A5061971998 @default.
• W4210910366 creator A5069770283 @default.
• W4210910366 creator A5074302829 @default.
• W4210910366 creator A5076726611 @default.
• W4210910366 creator A5082298463 @default.
• W4210910366 creator A5087839719 @default.
• W4210910366 date "2022-03-16" @default.
• W4210910366 modified "2023-09-27" @default.
• W4210910366 title "Multicenter Evaluation of the Acuitas AMR Gene Panel for Detection of an Extended Panel of Antimicrobial Resistance Genes among Bacterial Isolates" @default.
• W4210910366 cites W2008274231 @default.
• W4210910366 cites W2099837668 @default.
• W4210910366 cites W2124272787 @default.
• W4210910366 cites W2134852597 @default.
• W4210910366 cites W2135725736 @default.
• W4210910366 cites W2159643438 @default.
• W4210910366 cites W2163122583 @default.
• W4210910366 cites W2169583601 @default.
• W4210910366 cites W2177760960 @default.
• W4210910366 cites W2525326149 @default.
• W4210910366 cites W2569869334 @default.
• W4210910366 cites W2749173198 @default.
• W4210910366 cites W2784074338 @default.
• W4210910366 cites W2804051292 @default.
• W4210910366 cites W2900743550 @default.
• W4210910366 cites W2967682777 @default.
• W4210910366 cites W3094338265 @default.
• W4210910366 cites W3111589643 @default.
• W4210910366 cites W3118524433 @default.
• W4210910366 cites W3125138074 @default.
• W4210910366 cites W3195582817 @default.
• W4210910366 cites W3210833135 @default.
• W4210910366 doi "https://doi.org/10.1128/jcm.02098-21" @default.
• W4210910366 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35138924" @default.
• W4210910366 hasPublicationYear "2022" @default.
• W4210910366 type Work @default.
• W4210910366 citedByCount "2" @default.
• W4210910366 countsByYear W42109103662022 @default.
• W4210910366 countsByYear W42109103662023 @default.
• W4210910366 crossrefType "journal-article" @default.
• W4210910366 hasAuthorship W4210910366A5001896973 @default.
• W4210910366 hasAuthorship W4210910366A5011640815 @default.
• W4210910366 hasAuthorship W4210910366A5013216983 @default.
• W4210910366 hasAuthorship W4210910366A5025055624 @default.
• W4210910366 hasAuthorship W4210910366A5027534791 @default.
• W4210910366 hasAuthorship W4210910366A5037546003 @default.
• W4210910366 hasAuthorship W4210910366A5044556184 @default.
• W4210910366 hasAuthorship W4210910366A5045120202 @default.
• W4210910366 hasAuthorship W4210910366A5047176330 @default.
• W4210910366 hasAuthorship W4210910366A5055687038 @default.
• W4210910366 hasAuthorship W4210910366A5057106696 @default.
• W4210910366 hasAuthorship W4210910366A5061971998 @default.
• W4210910366 hasAuthorship W4210910366A5069770283 @default.
• W4210910366 hasAuthorship W4210910366A5074302829 @default.
• W4210910366 hasAuthorship W4210910366A5076726611 @default.
• W4210910366 hasAuthorship W4210910366A5082298463 @default.
• W4210910366 hasAuthorship W4210910366A5087839719 @default.
• W4210910366 hasBestOaLocation W42109103662 @default.
• W4210910366 hasConcept C104317684 @default.
• W4210910366 hasConcept C2777637488 @default.
• W4210910366 hasConcept C2779489039 @default.
• W4210910366 hasConcept C2779895986 @default.
• W4210910366 hasConcept C2781188995 @default.
• W4210910366 hasConcept C49105822 @default.
• W4210910366 hasConcept C4937899 @default.
• W4210910366 hasConcept C501593827 @default.
• W4210910366 hasConcept C523546767 @default.
• W4210910366 hasConcept C54355233 @default.
• W4210910366 hasConcept C86803240 @default.
• W4210910366 hasConcept C89423630 @default.
• W4210910366 hasConcept C90583042 @default.
• W4210910366 hasConcept C94665300 @default.
• W4210910366 hasConceptScore W4210910366C104317684 @default.
• W4210910366 hasConceptScore W4210910366C2777637488 @default.
• W4210910366 hasConceptScore W4210910366C2779489039 @default.
• W4210910366 hasConceptScore W4210910366C2779895986 @default.
• W4210910366 hasConceptScore W4210910366C2781188995 @default.
• W4210910366 hasConceptScore W4210910366C49105822 @default.
• W4210910366 hasConceptScore W4210910366C4937899 @default.
• W4210910366 hasConceptScore W4210910366C501593827 @default.
• W4210910366 hasConceptScore W4210910366C523546767 @default.
• W4210910366 hasConceptScore W4210910366C54355233 @default.
• W4210910366 hasConceptScore W4210910366C86803240 @default.
• W4210910366 hasConceptScore W4210910366C89423630 @default.
• W4210910366 hasConceptScore W4210910366C90583042 @default.
• W4210910366 hasConceptScore W4210910366C94665300 @default.
• W4210910366 hasIssue "3" @default.
• W4210910366 hasLocation W42109103661 @default.

• next