FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4210947313> ?p ?o ?g. }

• W4210947313 endingPage "1458" @default.
• W4210947313 startingPage "1453" @default.
• W4210947313 abstract "To investigate the risk factors that were associated with the death of elderly patients who were admitted to the intensive care unit (ICU) after elective abdominal surgery, and to find reliable and sensitive predictive indicators for early interventions and reducing the mortality.A retrospective case-control study was conducted. The clinical data of elderly (age ≥ 65 years old) patients after elective abdominal surgery admitted to the ICU of the Affiliated Hospital of Guizhou Medical University from January 1st 2016 to December 31st 2020 were collected, including the patient's gender, age, body mass index (BMI), medical history, American Society of Anesthesiologists (ASA) grades, surgical classification, intraoperative blood loss, duration of operation, interval time between end of operation and admission to the ICU, acute physiology and chronic health evaluation II (APACHE II) score and the worst laboratory examination results within 24 hours of ICU admission, the first blood gas analysis in ICU, the duration of invasive mechanical ventilation, and the length of ICU stay. Postoperative abdominal infection was evaluated by the pathogenic culture of peritoneal drainage fluid and clinical symptoms and signs. The patients were divided into death group and survival group based on clinical outcomes, and clinical data were compared between the two groups. Binary multivariate Logistic regression analysis was used to screen the risk factors of death, and the receiver operator characteristic curve (ROC curve) was plotted to analyze the predictive values of these risk factors.A total of 226 elderly patients with elective abdominal surgery were admitted to the ICU of our hospital during the past 5 years, of whom, two patients who did not undergo laboratory examinations within 24 hours of admission to the ICU were excluded. Finally, 224 patients met the criteria, with 158 survivors and 66 deaths. Univariate analysis showed that: compared with survival group, APACHE II score, blood lactate acid (Lac) and the proportion of postoperative abdominal infection were higher in death group [APACHE II score: 27.5 (25.0, 31.3) vs. 23.0 (18.0, 27.0), Lac (mmol/L): 2.9 (1.8, 6.6) vs. 1.8 (1.1, 2.8), the proportion of postoperative abdominal infection: 65.2% (43/66) vs. 35.4% (56/158), all P < 0.01], prothrombin time (PT), activated partial thromboplastin time (APTT) and interval time between end of surgery and admission to ICU were longer [PT (s): 17.20 (14.50, 18.63) vs. 14.65 (13.90, 16.23), APTT (s): 45.15 (38.68, 55.15) vs. 39.45 (36.40, 45.70), interval time between end of surgery and admission to ICU (hours): 39.2 (0.7, 128.9) vs. 0.7 (0.3, 2.0), all P < 0.01], postoperative hemoglobin (Hb), platelet count (PLT), prealbumin (PA), mean arterial pressure (MAP) and oxygenation index (PaO2/FiO2) were lower in death group [Hb (g/L): 95.79±23.64 vs. 105.58±19.82, PLT (×109/L): 138.5 (101.0, 177.5) vs. 160.5 (118.5, 232.3), PA (g/L): 80.88±43.63 vs. 116.54±50.80, MAP (mmHg, 1 mmHg = 0.133 kPa): 76.8±19.1 vs. 91.6±19.8, PaO2/FiO2 (mmHg): 180.0 (123.5, 242.5) vs. 223.5 (174.8, 310.0), all P < 0.05]. Binary multivariate Logistic regression analysis showed that APACHE II score [odds ratio (OR) = 1.187, 95% confidence interval (95%CI) = 1.008-1.294, P < 0.001], interval time between end of operation and admission to ICU (OR = 1.005, 95%CI = 1.001-1.009, P = 0.016) and postoperative abdominal infection (OR = 2.630, 95%CI = 1.148-6.024, P = 0.022) were independent risk factors for prognosis in these patients. MAP (OR = 0.978, 95%CI = 0.957-0.999, P = 0.041) and PaO2/FiO2 (OR = 0.994, 95%CI = 0.990-0.998, P = 0.003) were protective factors for the patients' prognosis. Lac, Hb, PLT, PA, PT and APTT had no predictive value for the prognosis of elderly patients admitted to ICU after elective abdominal surgery [OR value and 95%CI were 1.075 (0.945-1.223), 1.011 (0.99-1.032), 1.000 (0.995-1.005), 0.998 (0.989-1.007), 1.051 (0.927-1.192) and 1.003 (0.991-1.016), respectively, all P > 0.05. ROC curve analysis showed that APACHE II score, interval time between end of operation and admission to the ICU and the postoperative abdominal infection had certain predictive values for the prognosis of elderly patients, the area under ROC curve (AUC) were 0.755, 0.732 and 0.649 respectively, all P < 0.001; When the cut-off of APACHE II score and interval time between end of operation and admission to the ICU were 24.5 scores and 2.15 hours, the sensitivity were 78.8% and 66.7%, respectively, and the specificity were 62.0% and 76.6%, respectively. The combined predictive value of the three variables was the highest, which AUC was 0.846, the joint prediction probability was 0.27, the sensitivity was 83.3%, and the specificity was 75.3%.APACHE II score, interval time between end of surgery and admission to ICU, and postoperative abdominal infection may be independent risk factors for the death of elderly patients who were admitted to the ICU after elective abdominal surgery, there would be far greater predictive values when the three variables were combined." @default.
• W4210947313 created "2022-02-09" @default.
• W4210947313 creator A5003083504 @default.
• W4210947313 creator A5011968094 @default.
• W4210947313 creator A5016639443 @default.
• W4210947313 creator A5017318111 @default.
• W4210947313 creator A5019058819 @default.
• W4210947313 creator A5022021193 @default.
• W4210947313 creator A5033213179 @default.
• W4210947313 creator A5044100508 @default.
• W4210947313 creator A5080801658 @default.
• W4210947313 creator A5089824328 @default.
• W4210947313 date "2021-12-01" @default.
• W4210947313 modified "2023-09-28" @default.
• W4210947313 title "[Risk factors for death in elderly patients admitted to intensive care unit after elective abdominal surgery: a consecutive 5-year retrospective study]." @default.
• W4210947313 doi "https://doi.org/10.3760/cma.j.cn121430-20210804-00118" @default.
• W4210947313 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35131012" @default.
• W4210947313 hasPublicationYear "2021" @default.
• W4210947313 type Work @default.
• W4210947313 citedByCount "0" @default.
• W4210947313 crossrefType "journal-article" @default.
• W4210947313 hasAuthorship W4210947313A5003083504 @default.
• W4210947313 hasAuthorship W4210947313A5011968094 @default.
• W4210947313 hasAuthorship W4210947313A5016639443 @default.
• W4210947313 hasAuthorship W4210947313A5017318111 @default.
• W4210947313 hasAuthorship W4210947313A5019058819 @default.
• W4210947313 hasAuthorship W4210947313A5022021193 @default.
• W4210947313 hasAuthorship W4210947313A5033213179 @default.
• W4210947313 hasAuthorship W4210947313A5044100508 @default.
• W4210947313 hasAuthorship W4210947313A5080801658 @default.
• W4210947313 hasAuthorship W4210947313A5089824328 @default.
• W4210947313 hasConcept C126322002 @default.
• W4210947313 hasConcept C141071460 @default.
• W4210947313 hasConcept C151956035 @default.
• W4210947313 hasConcept C167135981 @default.
• W4210947313 hasConcept C177713679 @default.
• W4210947313 hasConcept C194828623 @default.
• W4210947313 hasConcept C2776376669 @default.
• W4210947313 hasConcept C2776890885 @default.
• W4210947313 hasConcept C2777080012 @default.
• W4210947313 hasConcept C2780120127 @default.
• W4210947313 hasConcept C2780221984 @default.
• W4210947313 hasConcept C2781312054 @default.
• W4210947313 hasConcept C71924100 @default.
• W4210947313 hasConceptScore W4210947313C126322002 @default.
• W4210947313 hasConceptScore W4210947313C141071460 @default.
• W4210947313 hasConceptScore W4210947313C151956035 @default.
• W4210947313 hasConceptScore W4210947313C167135981 @default.
• W4210947313 hasConceptScore W4210947313C177713679 @default.
• W4210947313 hasConceptScore W4210947313C194828623 @default.
• W4210947313 hasConceptScore W4210947313C2776376669 @default.
• W4210947313 hasConceptScore W4210947313C2776890885 @default.
• W4210947313 hasConceptScore W4210947313C2777080012 @default.
• W4210947313 hasConceptScore W4210947313C2780120127 @default.
• W4210947313 hasConceptScore W4210947313C2780221984 @default.
• W4210947313 hasConceptScore W4210947313C2781312054 @default.
• W4210947313 hasConceptScore W4210947313C71924100 @default.
• W4210947313 hasIssue "12" @default.
• W4210947313 hasLocation W42109473131 @default.
• W4210947313 hasOpenAccess W4210947313 @default.
• W4210947313 hasPrimaryLocation W42109473131 @default.
• W4210947313 hasRelatedWork W11618600 @default.
• W4210947313 hasRelatedWork W11630410 @default.
• W4210947313 hasRelatedWork W12469708 @default.
• W4210947313 hasRelatedWork W13762109 @default.
• W4210947313 hasRelatedWork W16432949 @default.
• W4210947313 hasRelatedWork W4366796 @default.
• W4210947313 hasRelatedWork W6752369 @default.
• W4210947313 hasRelatedWork W8399685 @default.
• W4210947313 hasRelatedWork W16761700 @default.
• W4210947313 hasRelatedWork W4339174 @default.
• W4210947313 hasVolume "33" @default.
• W4210947313 isParatext "false" @default.
• W4210947313 isRetracted "false" @default.
• W4210947313 workType "article" @default.