Matches in SemOpenAlex for { <https://semopenalex.org/work/W4210947334> ?p ?o ?g. }
- W4210947334 abstract "The reduction in postoperative complications is a considerable concern after orbital reparation and reconstruction. Selecting the appropriate scaffold materials to improve the survival rates of the seeded cells is a challenge in tissue engineering. The aim of the present study was to evaluate the biological activity of a vascular endothelial cell-hydroxyapatite orbital complex, which was constructed with tissue engineering and used as an implant after enucleation of the eyeNew Zealand white rabbits were randomly divided into two groups that underwent hydroxyapatite orbital implant surgery in the right eye. The primary orbital microvascular endothelial cells were collected from the microvascular tissue and subsequently cultured. Then, hydroxyapatite ocular implants were cultured with vascular endothelial cells in the endothelial cell (EC) group, and implants were cultured without vascular endothelial cells in the blank group. Characterization of the cells was performed with immunofluorescence staining and a Transwell migration and cell tube formation assay. The levels of interleukin-8 (IL-8) and vascular endothelial growth factor (VEGF) in the rabbit conjunctiva were measured with an ELISA. The results showed that the levels of IL-8 were decreased in the EC group and increased in the blank group. The levels of VEGF were increased in the EC group when compared to the blank group with statistical significance. The average depth of the fibrovascular tissue was obviously thicker in the EC group compared with that found in the blank group. These findings suggest that the vascular endothelial cell-hydroxyapatite orbital implant complex may be an effective strategy with which to accelerate vascularization and reduce complications of infection with satisfactory biological activity." @default.
- W4210947334 created "2022-02-09" @default.
- W4210947334 creator A5000538686 @default.
- W4210947334 creator A5023501474 @default.
- W4210947334 creator A5047936761 @default.
- W4210947334 creator A5075189241 @default.
- W4210947334 creator A5078817991 @default.
- W4210947334 creator A5085774992 @default.
- W4210947334 date "2022-01-18" @default.
- W4210947334 modified "2023-10-06" @default.
- W4210947334 title "Biological activity of a vascular endothelial cell‑hydroxyapatite orbital implant complex: An experimental study" @default.
- W4210947334 cites W1220478372 @default.
- W4210947334 cites W143973521 @default.
- W4210947334 cites W1784039464 @default.
- W4210947334 cites W1969094201 @default.
- W4210947334 cites W1978583697 @default.
- W4210947334 cites W1981013883 @default.
- W4210947334 cites W2003919623 @default.
- W4210947334 cites W2017341410 @default.
- W4210947334 cites W2027960289 @default.
- W4210947334 cites W2030544916 @default.
- W4210947334 cites W2042812804 @default.
- W4210947334 cites W2047438155 @default.
- W4210947334 cites W2058349424 @default.
- W4210947334 cites W2066518402 @default.
- W4210947334 cites W2073872114 @default.
- W4210947334 cites W2074434016 @default.
- W4210947334 cites W2086906910 @default.
- W4210947334 cites W2109154357 @default.
- W4210947334 cites W2192349295 @default.
- W4210947334 cites W2193257617 @default.
- W4210947334 cites W2319562462 @default.
- W4210947334 cites W2319854164 @default.
- W4210947334 cites W2323575471 @default.
- W4210947334 cites W2410153082 @default.
- W4210947334 cites W2471954596 @default.
- W4210947334 cites W2521867133 @default.
- W4210947334 cites W2541187389 @default.
- W4210947334 cites W2555460407 @default.
- W4210947334 cites W2751818375 @default.
- W4210947334 cites W2769886493 @default.
- W4210947334 cites W2792345613 @default.
- W4210947334 cites W2800933975 @default.
- W4210947334 cites W2806126488 @default.
- W4210947334 cites W2904950582 @default.
- W4210947334 cites W2917710461 @default.
- W4210947334 cites W2958779309 @default.
- W4210947334 cites W2972642945 @default.
- W4210947334 cites W3003809815 @default.
- W4210947334 cites W3025487456 @default.
- W4210947334 cites W3032937026 @default.
- W4210947334 cites W3038356178 @default.
- W4210947334 cites W3087869764 @default.
- W4210947334 cites W2084416384 @default.
- W4210947334 doi "https://doi.org/10.3892/etm.2022.11152" @default.
- W4210947334 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35222704" @default.
- W4210947334 hasPublicationYear "2022" @default.
- W4210947334 type Work @default.
- W4210947334 citedByCount "0" @default.
- W4210947334 crossrefType "journal-article" @default.
- W4210947334 hasAuthorship W4210947334A5000538686 @default.
- W4210947334 hasAuthorship W4210947334A5023501474 @default.
- W4210947334 hasAuthorship W4210947334A5047936761 @default.
- W4210947334 hasAuthorship W4210947334A5075189241 @default.
- W4210947334 hasAuthorship W4210947334A5078817991 @default.
- W4210947334 hasAuthorship W4210947334A5085774992 @default.
- W4210947334 hasBestOaLocation W42109473341 @default.
- W4210947334 hasConcept C123012128 @default.
- W4210947334 hasConcept C126322002 @default.
- W4210947334 hasConcept C136229726 @default.
- W4210947334 hasConcept C141071460 @default.
- W4210947334 hasConcept C142724271 @default.
- W4210947334 hasConcept C16685009 @default.
- W4210947334 hasConcept C167734588 @default.
- W4210947334 hasConcept C185592680 @default.
- W4210947334 hasConcept C188261085 @default.
- W4210947334 hasConcept C202751555 @default.
- W4210947334 hasConcept C2776992346 @default.
- W4210947334 hasConcept C2777025900 @default.
- W4210947334 hasConcept C2780394083 @default.
- W4210947334 hasConcept C2781411149 @default.
- W4210947334 hasConcept C49892992 @default.
- W4210947334 hasConcept C55493867 @default.
- W4210947334 hasConcept C71924100 @default.
- W4210947334 hasConceptScore W4210947334C123012128 @default.
- W4210947334 hasConceptScore W4210947334C126322002 @default.
- W4210947334 hasConceptScore W4210947334C136229726 @default.
- W4210947334 hasConceptScore W4210947334C141071460 @default.
- W4210947334 hasConceptScore W4210947334C142724271 @default.
- W4210947334 hasConceptScore W4210947334C16685009 @default.
- W4210947334 hasConceptScore W4210947334C167734588 @default.
- W4210947334 hasConceptScore W4210947334C185592680 @default.
- W4210947334 hasConceptScore W4210947334C188261085 @default.
- W4210947334 hasConceptScore W4210947334C202751555 @default.
- W4210947334 hasConceptScore W4210947334C2776992346 @default.
- W4210947334 hasConceptScore W4210947334C2777025900 @default.
- W4210947334 hasConceptScore W4210947334C2780394083 @default.
- W4210947334 hasConceptScore W4210947334C2781411149 @default.
- W4210947334 hasConceptScore W4210947334C49892992 @default.
- W4210947334 hasConceptScore W4210947334C55493867 @default.