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- W4210984865 abstract "Characterizing relationships between cell structures and functions requires quantitative mesoscale mapping of intact cells showing subcellular rearrangements following stimulation; however, current approaches are limited in this regard. Thus, we investigated the application of soft X-ray tomography to generate three-dimensional reconstructions of whole pancreatic β-cells at different timepoints following glucose-stimulated insulin secretion. Reconstructions following stimulation show distinct insulin vesicle distribution patterns reflective of altered vesicle pool sizes as they mature and travel through the secretory pathway." @default.
- W4210984865 created "2022-02-13" @default.
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- W4210984865 date "2022-02-01" @default.
- W4210984865 modified "2023-10-14" @default.
- W4210984865 title "Use of soft X-ray tomography to capture the dynamic biochemical nature of intact pancreatic beta cells" @default.
- W4210984865 doi "https://doi.org/10.1016/j.bpj.2021.11.1288" @default.
- W4210984865 hasPublicationYear "2022" @default.
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