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- W4210992509 endingPage "464" @default.
- W4210992509 startingPage "444" @default.
- W4210992509 abstract "The composition and definition of functional esophageal disorders have evolved over the years, primarily driven by the widely accepted Rome criteria. Presently, there are five functional esophageal disorders: functional heartburn, functional chest pain, reflux hypersensitivity, globus, and functional dysphagia. Refractory gastroesophageal reflux disease (GERD) and refractory heartburn have been used interchangeably in patients who are not responsive to twice-daily proton pump inhibitor (PPI) therapy. Rome IV introduced a new concept that was not mentioned in the previous Rome criteria, which stated that functional esophageal disorders, specifically functional heartburn and reflux hypersensitivity, may overlap with GERD. Comparison of reflux characteristics between GERD patients who are fully responsive to once-daily PPI versus those who failed to respond, using a combination of 24-hour pH test and Billitec, revealed a similar distribution of duodeno-gastroesophageal and acidic reflux in both groups." @default.
- W4210992509 created "2022-02-13" @default.
- W4210992509 creator A5022335823 @default.
- W4210992509 creator A5044763833 @default.
- W4210992509 date "2021-04-30" @default.
- W4210992509 modified "2023-09-28" @default.
- W4210992509 title "Refractory Heartburn" @default.
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