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- W4211008694 abstract "High-throughput screening (HTS) is crucial to the drug discovery process enabling rapid development of drug leads and reducing costs associated with optimization of drug activity. Calorimetry is a label-free, biophysical technique used for determination of important parameters associated with drug-protein interactions, such as binding affinity and thermodynamics. However, conventional isothermal titration calorimetry (ITC) is limited by low throughput, high sample consumption (milliliters), and long measurement time (tens of minutes)." @default.
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- W4211008694 date "2022-02-01" @default.
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- W4211008694 title "An optical microfluidic calorimeter for high-throughput drug screening" @default.
- W4211008694 doi "https://doi.org/10.1016/j.bpj.2021.11.692" @default.
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