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- W4211012025 abstract "Alopecia areata is an autoimmune disorder characterized by transient, non-scarring hair loss and preservation of the hair follicle. Hair loss can take many forms ranging from loss in well-defined patches to diffuse or total hair loss, which can affect all hair-bearing sites. Patchy alopecia areata affecting the scalp is the most common type. Alopecia areata affects nearly 2% of the general population at some point during their lifetime. Skin biopsies of affected skin show a lymphocytic infiltrate in and around the bulb or the lower part of the hair follicle in the anagen (hair growth) phase. A breakdown of immune privilege of the hair follicle is thought to be an important driver of alopecia areata. Genetic studies in patients and mouse models have shown that alopecia areata is a complex, polygenic disease. Several genetic susceptibility loci were identified to be associated with signalling pathways that are important to hair follicle cycling and development. Alopecia areata is usually diagnosed based on clinical manifestations, but dermoscopy and histopathology can be helpful. Alopecia areata is difficult to manage medically, but recent advances in understanding the molecular mechanisms have revealed new treatments and the possibility of remission in the near future. Alopecia areata is an autoimmune disorder characterized by transient hair loss. Severity can range from distinct patches to total hair loss. In this Primer, the authors describe the underlying pathophysiology of this complex polygenic disease, as well as the epidemiology, diagnosis and management." @default.
- W4211012025 created "2022-02-13" @default.
- W4211012025 creator A5020622342 @default.
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- W4211012025 creator A5044490713 @default.
- W4211012025 creator A5045803710 @default.
- W4211012025 creator A5078351171 @default.
- W4211012025 date "2017-03-16" @default.
- W4211012025 modified "2023-10-14" @default.
- W4211012025 title "Alopecia areata" @default.
- W4211012025 cites W111715119 @default.
- W4211012025 cites W114101100 @default.
- W4211012025 cites W1501300864 @default.
- W4211012025 cites W1505685427 @default.
- W4211012025 cites W1513566870 @default.
- W4211012025 cites W1516188244 @default.
- W4211012025 cites W1537167162 @default.
- W4211012025 cites W1574219574 @default.
- W4211012025 cites W1575654393 @default.
- W4211012025 cites W1592870917 @default.
- W4211012025 cites W159556166 @default.
- W4211012025 cites W1599849158 @default.
- W4211012025 cites W169108696 @default.
- W4211012025 cites W1728469544 @default.
- W4211012025 cites W178764668 @default.
- W4211012025 cites W1819192711 @default.
- W4211012025 cites W1824244227 @default.
- W4211012025 cites W1852206426 @default.
- W4211012025 cites W1859279895 @default.
- W4211012025 cites W1963687181 @default.
- W4211012025 cites W1963845724 @default.
- W4211012025 cites W1964849104 @default.
- W4211012025 cites W1964992028 @default.
- W4211012025 cites W1965723351 @default.
- W4211012025 cites W1965924746 @default.
- W4211012025 cites W1966059955 @default.
- W4211012025 cites W1968511049 @default.
- W4211012025 cites W1969900831 @default.
- W4211012025 cites W1970729752 @default.
- W4211012025 cites W1971314903 @default.
- W4211012025 cites W1972331016 @default.
- W4211012025 cites W1974722772 @default.
- W4211012025 cites W1975416466 @default.
- W4211012025 cites W1977333143 @default.
- W4211012025 cites W1978020207 @default.
- W4211012025 cites W1978239858 @default.
- W4211012025 cites W1978344266 @default.
- W4211012025 cites W1986786571 @default.
- W4211012025 cites W1986888030 @default.
- W4211012025 cites W1987231258 @default.
- W4211012025 cites W1987405614 @default.
- W4211012025 cites W1988045077 @default.
- W4211012025 cites W1988918830 @default.
- W4211012025 cites W1990479231 @default.
- W4211012025 cites W1992025886 @default.
- W4211012025 cites W1993585430 @default.
- W4211012025 cites W1995512868 @default.
- W4211012025 cites W1996718217 @default.
- W4211012025 cites W1997494609 @default.
- W4211012025 cites W1997638308 @default.
- W4211012025 cites W1997942637 @default.
- W4211012025 cites W1998220547 @default.
- W4211012025 cites W1999290360 @default.
- W4211012025 cites W2001962744 @default.
- W4211012025 cites W2002787950 @default.
- W4211012025 cites W2002818004 @default.
- W4211012025 cites W2004244822 @default.
- W4211012025 cites W2005827387 @default.
- W4211012025 cites W2010762002 @default.
- W4211012025 cites W2013074049 @default.
- W4211012025 cites W2015692547 @default.
- W4211012025 cites W2015733931 @default.
- W4211012025 cites W201689951 @default.
- W4211012025 cites W2017176414 @default.
- W4211012025 cites W2018360785 @default.
- W4211012025 cites W2019237002 @default.
- W4211012025 cites W2020899794 @default.
- W4211012025 cites W2022805065 @default.
- W4211012025 cites W2024615255 @default.
- W4211012025 cites W2026224300 @default.
- W4211012025 cites W2026492475 @default.
- W4211012025 cites W2027384265 @default.
- W4211012025 cites W2027787653 @default.
- W4211012025 cites W2028286837 @default.
- W4211012025 cites W2029197763 @default.
- W4211012025 cites W2030447176 @default.
- W4211012025 cites W2035014654 @default.
- W4211012025 cites W2037365204 @default.
- W4211012025 cites W2037548712 @default.
- W4211012025 cites W2039926800 @default.
- W4211012025 cites W2040036851 @default.
- W4211012025 cites W2041980962 @default.
- W4211012025 cites W2042139699 @default.
- W4211012025 cites W2042445209 @default.
- W4211012025 cites W2043072893 @default.
- W4211012025 cites W2044535212 @default.
- W4211012025 cites W2045382802 @default.
- W4211012025 cites W2045721954 @default.
- W4211012025 cites W2046839005 @default.
- W4211012025 cites W2048128167 @default.