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- W4211030376 abstract "Mitochondrial associated membranes (MAM) provide a platform for crosstalk between the endoplasmic reticulum (ER) and mitochondria to regulate ER/mitochondria structure and function. In cardiac ischemia-reperfusion (IR) injury, ER-mitochondria interaction is known to contribute to the pathology via causing ER stress, mitochondrial morphology changes, apoptosis, and redox imbalance. Ion channels including chloride channels are implicated in cardioprotection from IR injury. Apart from VDAC1, no other chloride channels at the ER contact site of MAM have been identified to determine cardiac response to IR injury." @default.
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- W4211030376 date "2022-02-01" @default.
- W4211030376 modified "2023-09-28" @default.
- W4211030376 title "A novel mitochondrial associated membrane chloride channel, clic4, in cardio-protection from ischemia-reperfusion injury" @default.
- W4211030376 doi "https://doi.org/10.1016/j.bpj.2021.11.238" @default.
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