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• W4211033689 abstract "Exposure to beryllium remains a significant occupational hazard, clinically resulting in berylliosis, or chronic beryllium disease (CBD). This scarring lung disease is an interstitial lung disease characterized by granulomatous inflammation that affects 2–10% of those exposed. Serving as a model for other granulomatous disease, CBD provides an example of an exposure-related disease that results from an environmental–genetic interaction. The development of CBD requires both a genetic predisposition, namely a major histocompatibility complex (MHC Class II) allele of HLA-DPB1 with a glutamic acid at amino acid position 69 (glu69), as well as exposure to beryllium. The precursor to CBD, beryllium sensitization (BeS), is defined by the demonstration of a beryllium-specific cell-mediated immunity using the beryllium lymphocyte proliferation test (BeLPT), a test which provides clinicians the ability to differentiate CBD from similar granulomatous diseases. CBD is characterized by the presence of sensitized T-lymphocytes with Th1 cytokine production. Like many granulomatous diseases, CBD has a variable course, and although immunosuppressive drugs may be beneficial in some individuals, the disease has no cure. Thus, the focus on decreasing the prevalence of CBD relies on improving prevention in the workplace. This chapter will outline the potential for workplace exposure to beryllium as well as the immunopathogenesis, clinical manifestations, diagnosis, and current treatment of BeS and CBD." @default.
• W4211033689 created "2022-02-13" @default.
• W4211033689 creator A5056329351 @default.
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• W4211033689 date "2012-01-01" @default.
• W4211033689 modified "2023-09-24" @default.
• W4211033689 title "Beryllium Disease" @default.
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• W4211033689 cites W1971704434 @default.
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• W4211033689 cites W1978475272 @default.
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• W4211033689 cites W1989992384 @default.
• W4211033689 cites W1990884623 @default.
• W4211033689 cites W1991211900 @default.
• W4211033689 cites W1995722330 @default.
• W4211033689 cites W1998984160 @default.
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• W4211033689 cites W2005358773 @default.
• W4211033689 cites W2005380262 @default.
• W4211033689 cites W2006539372 @default.
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• W4211033689 cites W2037451648 @default.
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• W4211033689 doi "https://doi.org/10.1007/978-1-62703-149-3_12" @default.
• W4211033689 hasPublicationYear "2012" @default.
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