Matches in SemOpenAlex for { <https://semopenalex.org/work/W4211079548> ?p ?o ?g. }
- W4211079548 endingPage "410" @default.
- W4211079548 startingPage "410" @default.
- W4211079548 abstract "Anthropogenic ultrafine particulate matter (UFPM) and industrial and natural nanoparticles (NPs) are ubiquitous. Normal term, preeclamptic, and postconceptional weeks(PCW) 8-15 human placentas and brains from polluted Mexican cities were analyzed by TEM and energy-dispersive X-ray spectroscopy. We documented NPs in maternal erythrocytes, early syncytiotrophoblast, Hofbauer cells, and fetal endothelium (ECs). Fetal ECs exhibited caveolar NP activity and widespread erythroblast contact. Brain ECs displayed micropodial extensions reaching luminal NP-loaded erythroblasts. Neurons and primitive glia displayed nuclear, organelle, and cytoplasmic NPs in both singles and conglomerates. Nanoscale Fe, Ti, and Al alloys, Hg, Cu, Ca, Sn, and Si were detected in placentas and fetal brains. Preeclamptic fetal blood NP vesicles are prospective neonate UFPM exposure biomarkers. NPs are reaching brain tissues at the early developmental PCW 8-15 stage, and NPs in maternal and fetal placental tissue compartments strongly suggests the placental barrier is not limiting the access of environmental NPs. Erythroblasts are the main early NP carriers to fetal tissues. The passage of UFPM/NPs from mothers to fetuses is documented and fingerprinting placental single particle composition could be useful for postnatal risk assessments. Fetal brain combustion and industrial NPs raise medical concerns about prenatal and postnatal health, including neurological and neurodegenerative lifelong consequences." @default.
- W4211079548 created "2022-02-13" @default.
- W4211079548 creator A5016402542 @default.
- W4211079548 creator A5017464998 @default.
- W4211079548 creator A5026862828 @default.
- W4211079548 creator A5027414918 @default.
- W4211079548 creator A5036064445 @default.
- W4211079548 creator A5039282161 @default.
- W4211079548 creator A5041027914 @default.
- W4211079548 creator A5043213302 @default.
- W4211079548 creator A5076335755 @default.
- W4211079548 creator A5080526168 @default.
- W4211079548 creator A5084810564 @default.
- W4211079548 date "2022-02-09" @default.
- W4211079548 modified "2023-10-18" @default.
- W4211079548 title "Environmental Nanoparticles Reach Human Fetal Brains" @default.
- W4211079548 cites W1489887382 @default.
- W4211079548 cites W1603377221 @default.
- W4211079548 cites W1970129963 @default.
- W4211079548 cites W1990689226 @default.
- W4211079548 cites W1992758695 @default.
- W4211079548 cites W2040330912 @default.
- W4211079548 cites W2056499064 @default.
- W4211079548 cites W2067037001 @default.
- W4211079548 cites W2074467897 @default.
- W4211079548 cites W2079774670 @default.
- W4211079548 cites W2087634817 @default.
- W4211079548 cites W2120553873 @default.
- W4211079548 cites W2123948966 @default.
- W4211079548 cites W2125737877 @default.
- W4211079548 cites W2139646490 @default.
- W4211079548 cites W2165313572 @default.
- W4211079548 cites W2298212394 @default.
- W4211079548 cites W2301631169 @default.
- W4211079548 cites W2337369609 @default.
- W4211079548 cites W2399942170 @default.
- W4211079548 cites W2417190922 @default.
- W4211079548 cites W2508267476 @default.
- W4211079548 cites W2547515423 @default.
- W4211079548 cites W2559747784 @default.
- W4211079548 cites W2576635117 @default.
- W4211079548 cites W2603292174 @default.
- W4211079548 cites W2614148033 @default.
- W4211079548 cites W2615272798 @default.
- W4211079548 cites W2664009300 @default.
- W4211079548 cites W2684185642 @default.
- W4211079548 cites W2759050422 @default.
- W4211079548 cites W2767784465 @default.
- W4211079548 cites W2775815660 @default.
- W4211079548 cites W2788681466 @default.
- W4211079548 cites W2792100562 @default.
- W4211079548 cites W2792461757 @default.
- W4211079548 cites W2794395831 @default.
- W4211079548 cites W2900756811 @default.
- W4211079548 cites W2907254967 @default.
- W4211079548 cites W2923028656 @default.
- W4211079548 cites W2942285388 @default.
- W4211079548 cites W2953719812 @default.
- W4211079548 cites W2956329509 @default.
- W4211079548 cites W2962962014 @default.
- W4211079548 cites W2969537998 @default.
- W4211079548 cites W2970310584 @default.
- W4211079548 cites W2974156380 @default.
- W4211079548 cites W2975263862 @default.
- W4211079548 cites W2977331048 @default.
- W4211079548 cites W2980677147 @default.
- W4211079548 cites W3002628762 @default.
- W4211079548 cites W3009960475 @default.
- W4211079548 cites W3015471324 @default.
- W4211079548 cites W3027034786 @default.
- W4211079548 cites W3027916577 @default.
- W4211079548 cites W3029263718 @default.
- W4211079548 cites W3036190216 @default.
- W4211079548 cites W3039825626 @default.
- W4211079548 cites W3041102054 @default.
- W4211079548 cites W3045457025 @default.
- W4211079548 cites W3046040291 @default.
- W4211079548 cites W3047493257 @default.
- W4211079548 cites W3049569700 @default.
- W4211079548 cites W3081148803 @default.
- W4211079548 cites W3081795384 @default.
- W4211079548 cites W3082604457 @default.
- W4211079548 cites W3086513453 @default.
- W4211079548 cites W3092095836 @default.
- W4211079548 cites W3092742419 @default.
- W4211079548 cites W3093421085 @default.
- W4211079548 cites W3097147482 @default.
- W4211079548 cites W3104212706 @default.
- W4211079548 cites W3108468336 @default.
- W4211079548 cites W3108693772 @default.
- W4211079548 cites W3110684703 @default.
- W4211079548 cites W3110925142 @default.
- W4211079548 cites W3111112521 @default.
- W4211079548 cites W3111382259 @default.
- W4211079548 cites W3113117100 @default.
- W4211079548 cites W3121627202 @default.
- W4211079548 cites W3122858439 @default.
- W4211079548 cites W3123931809 @default.