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- W4211083036 abstract "A diverse community makes up the normal healthy microbiota in humans, and anaerobic bacteria are the primary component (1–4). A wide variety of different environments in the human body support complex microbial communities comprising both obligate and facultative anaerobes (3 , 4). At all body sites where anaerobes are part of the indigenous microbiota, obligate anaerobes greatly outnumber facultative anaerobes by a factor of 10 up to 1,000 times (Table 1) (5–9). Obligate anaerobes are therefore the predominant type of bacteria present in humans at skin and mucosal surfaces. Microbial-community analysis of healthy human intestinal microbiota also reveals a rich and diverse array of anaerobes including Lactobacillus spp., members of the former Bacteroides fragilis group (i.e., B. fragilis, B. distasonis, B. thetaiotaomicron, B. ovatus, and B. vulgatus), other Bacteroides species, and Clostridium spp., as well as a wide array of anaerobes that are less clinically encountered (2, 10, 11). Under normal circumstances, intestinal anaerobes are not pathogenic but are essential for preventing overgrowth of opportunistic organisms or infection with pathogenic bacteria. Colonization resistance against acquisition of enteric pathogens (i.e., Salmonella and Shigella) and hospital-acquired antibiotic-resistant bacteria (e.g., vancomycin-resistant enterococci and Clostridium difficile) is provided by the presence of healthy normal bacteria that prevent gastrointestinal colonization by exogenous bacteria (1, 10, 12–18)." @default.
- W4211083036 created "2022-02-13" @default.
- W4211083036 creator A5072861045 @default.
- W4211083036 date "2016-04-15" @default.
- W4211083036 modified "2023-09-29" @default.
- W4211083036 title "Selected Topics in Anaerobic Bacteriology" @default.
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